Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia
出版年份 2017 全文链接
标题
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume 27, Issue 1, Pages 1-13
出版商
Oxford University Press (OUP)
发表日期
2017-10-04
DOI
10.1093/hmg/ddx374
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Cilium: Cellular Antenna and Central Processing Unit
- (2017) Jarema J. Malicki et al. TRENDS IN CELL BIOLOGY
- Primary cilium and autophagy: The avengers of cell-size regulation
- (2016) Idil Orhon et al. Autophagy
- Autophagy and primary cilia: dual interplay
- (2016) Olatz Pampliega et al. CURRENT OPINION IN CELL BIOLOGY
- Effectors of mTOR-autophagy pathway: targeting cancer, affecting the skeleton
- (2016) Andrei S Chagin CURRENT OPINION IN PHARMACOLOGY
- IFT52mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndrome
- (2016) Wenjuan Zhang et al. HUMAN MOLECULAR GENETICS
- Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway
- (2016) Sicong Jiang et al. Molecular Medicine Reports
- IFT88 influences chondrocyte actin organization and biomechanics
- (2016) Z. Wang et al. OSTEOARTHRITIS AND CARTILAGE
- Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development
- (2016) Kazuo Noda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation
- (2016) Bo Yan et al. Nature Communications
- A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi
- (2016) Corinne Stoetzel et al. Nature Communications
- Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice
- (2016) Honghao Zhang et al. PLoS Genetics
- FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia
- (2015) Xiaofeng Wang et al. Autophagy
- Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways
- (2015) Shixuan Wang et al. Autophagy
- Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells
- (2015) Ji Hyun Shin et al. Biomolecules & Therapeutics
- Assembly of IFT Trains at the Ciliary Base Depends on IFT74
- (2015) Jason M. Brown et al. CURRENT BIOLOGY
- Fibroblast growth factor signaling in skeletal development and disease
- (2015) David M. Ornitz et al. GENES & DEVELOPMENT
- Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation
- (2015) Karuna K Vuppalapati et al. JOURNAL OF BONE AND MINERAL RESEARCH
- FGF signalling regulates bone growth through autophagy
- (2015) Laura Cinque et al. NATURE
- Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome
- (2015) S. Paige Taylor et al. Nature Communications
- Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization
- (2015) Albane A. Bizet et al. Nature Communications
- Function and regulation of primary cilia and intraflagellar transport proteins in the skeleton
- (2014) Xue Yuan et al. Annals of the New York Academy of Sciences
- Self-eating to remove cilia roadblock
- (2014) Zaiming Tang et al. Autophagy
- Autophagy and regulation of cilia function and assembly
- (2014) I Orhon et al. CELL DEATH AND DIFFERENTIATION
- The growth plate’s response to load is partially mediated by mechano-sensing via the chondrocytic primary cilium
- (2014) Yoach Rais et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Primary Cilia in the Developing and Mature Brain
- (2014) Alicia Guemez-Gamboa et al. NEURON
- From the Radiologic Pathology Archives: Pediatric Polycystic Kidney Disease and Other Ciliopathies: Radiologic-Pathologic Correlation
- (2014) Ellen M. Chung et al. RADIOGRAPHICS
- Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension
- (2014) Kousuke Kasahara et al. Nature Communications
- From the cytoplasm into the cilium: Bon voyage
- (2014) Jarema Malicki et al. Organogenesis
- Defects in the IFT-B Component IFT172 Cause Jeune and Mainzer-Saldino Syndromes in Humans
- (2013) Jan Halbritter et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Exome sequencing identifiesDYNC2H1mutations as a common cause of asphyxiating thoracic dystrophy (Jeune syndrome) without major polydactyly, renal or retinal involvement
- (2013) Miriam Schmidts et al. JOURNAL OF MEDICAL GENETICS
- Ciliary disorder of the skeleton
- (2012) Celine Huber et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- Ciliopathies with Skeletal Anomalies and Renal Insufficiency due to Mutations in the IFT-A Gene WDR19
- (2011) Cecilie Bredrup et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Architecture and function of IFT complex proteins in ciliogenesis
- (2011) Michael Taschner et al. DIFFERENTIATION
- A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model
- (2011) Aurélie Jonquoy et al. HUMAN MOLECULAR GENETICS
- C14ORF179 encoding IFT43 is mutated in Sensenbrenner syndrome
- (2011) H. H. Arts et al. JOURNAL OF MEDICAL GENETICS
- An actin-dependent mechanism for long-range vesicle transport
- (2011) Melina Schuh NATURE CELL BIOLOGY
- A Variant of Fibroblast Growth Factor Receptor 2 (Fgfr2) Regulates Left-Right Asymmetry in Zebrafish
- (2011) Da-Wei Liu et al. PLoS One
- Craniofacial ciliopathies: A new classification for craniofacial disorders
- (2010) Samantha A. Brugmann et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Functional genomic screen for modulators of ciliogenesis and cilium length
- (2010) Joon Kim et al. NATURE
- Primary cilia regulate mTORC1 activity and cell size through Lkb1
- (2010) Christopher Boehlke et al. NATURE CELL BIOLOGY
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- FGF signalling during embryo development regulates cilia length in diverse epithelia
- (2009) Judith M. Neugebauer et al. NATURE
- Achondroplasia
- (2008) Geneviève Baujat et al. BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
- Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia
- (2008) Stéphanie Pannier et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Golgin GMAP210/TRIP11 Anchors IFT20 to the Golgi Complex
- (2008) John A. Follit et al. PLoS Genetics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started