Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice
出版年份 2016 全文链接
标题
Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice
作者
关键词
Growth plate, Hedgehog signaling, Chondrocytes, Perichondrium, Dwarfism, Tibia, Achondroplasia, Cilia
出版物
PLoS Genetics
Volume 12, Issue 12, Pages e1006510
出版商
Public Library of Science (PLoS)
发表日期
2017-01-10
DOI
10.1371/journal.pgen.1006510
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth
- (2016) Kannan Karuppaiah et al. DEVELOPMENT
- A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development
- (2016) Irene H. Hung et al. DEVELOPMENTAL BIOLOGY
- Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis
- (2015) S. Hayano et al. DEVELOPMENT
- Fibroblast growth factor signaling in skeletal development and disease
- (2015) David M. Ornitz et al. GENES & DEVELOPMENT
- Generation ofEvc2/Limbinglobal and conditional KO mice and its roles during mineralized tissue formation
- (2015) Honghao Zhang et al. GENESIS
- EFCAB7 and IQCE Regulate Hedgehog Signaling by Tethering the EVC-EVC2 Complex to the Base of Primary Cilia
- (2014) Ganesh V. Pusapati et al. DEVELOPMENTAL CELL
- Deletion in the EVC2 Gene Causes Chondrodysplastic Dwarfism in Tyrolean Grey Cattle
- (2014) Leonardo Murgiano et al. PLoS One
- Development of the Endochondral Skeleton
- (2013) F. Long et al. Cold Spring Harbor Perspectives in Biology
- Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2
- (2012) Cuiping Yang et al. CELL RESEARCH
- A Smoothened-Evc2 Complex Transduces the Hedgehog Signal at Primary Cilia
- (2012) Karolin V. Dorn et al. DEVELOPMENTAL CELL
- Sox9 Directs Hypertrophic Maturation and Blocks Osteoblast Differentiation of Growth Plate Chondrocytes
- (2012) Peter Dy et al. DEVELOPMENTAL CELL
- The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia
- (2012) Jose A. Caparrós-Martín et al. HUMAN MOLECULAR GENETICS
- Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus
- (2011) Helen J Blair et al. BMC BIOLOGY
- The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
- (2010) E. W. Humke et al. GENES & DEVELOPMENT
- A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes
- (2010) Hanna Tukachinsky et al. JOURNAL OF CELL BIOLOGY
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- FGF signalling during embryo development regulates cilia length in diverse epithelia
- (2009) Judith M. Neugebauer et al. NATURE
- Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
- (2009) J. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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