Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances

The effect of past antibiotic exposure on diabetes risk

(2015) B. Boursi et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Alarmingly High Segregation Frequencies of Quinolone Resistance Alleles within Human and Animal Microbiomes Are Not Explained by Direct Clinical Antibiotic Exposure

(2015) Wesley Field et al.   Genome Biology and Evolution

Antibiotics promote inflammation through the translocation of native commensal colonic bacteria

(2015) Kathryn A Knoop et al.   GUT

Sequencing and beyond: integrating molecular 'omics' for microbial community profiling

(2015) Eric A. Franzosa et al.   NATURE REVIEWS MICROBIOLOGY

Gut resistome development in healthy twin pairs in the first year of life

(2015) Aimee M. Moore et al.   Microbiome

Antibiotics in Early Life Alter the Gut Microbiome and Increase Disease Incidence in a Spontaneous Mouse Model of Autoimmune Insulin-Dependent Diabetes

(2015) Sophie Candon et al.   PLoS One

A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and β-lactam resistance genes in the gut microbiota

(2014) Fiona Fouhy et al.   BMC MICROBIOLOGY

The balance of intestinal Foxp3+regulatory T cells and Th17 cells and its biological significance

(2014) Xiaofei Shen et al.   Expert Review of Clinical Immunology

In Silico Analysis of Antibiotic Resistance Genes in the Gut Microflora of Individuals from Diverse Geographies and Age-Groups

(2014) Tarini Shankar Ghosh et al.   PLoS One

Application of Microarray and Functional-Based Screening Methods for the Detection of Antimicrobial Resistance Genes in the Microbiomes of Healthy Humans

(2014) Roderick M. Card et al.   PLoS One

Identification of Aminoglycoside and β-Lactam Resistance Genes from within an Infant Gut Functional Metagenomic Library

(2014) Fiona Fouhy et al.   PLoS One

The Placenta Harbors a Unique Microbiome

(2014) K. Aagaard et al.   Science Translational Medicine

DNA microarray analysis reveals that antibiotic resistance-gene diversity in human gut microbiota is age related

(2014) Na Lu et al.   Scientific Reports

Tetracycline resistance genes acquired at birth

(2013) Angela M. Alicea-Serrano et al.   ARCHIVES OF MICROBIOLOGY

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

Country-specific antibiotic use practices impact the human gut resistome

(2013) K. Forslund et al.   GENOME RESEARCH

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

(2013) Anne Vrieze et al.   JOURNAL OF HEPATOLOGY

Early life exposure to antibiotics and the risk of childhood allergic diseases: An update from the perspective of the hygiene hypothesis

(2013) Chang-Hung Kuo et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Proteomic Comparison of Historic and Recently Emerged Hypervirulent Clostridium difficile Strains

(2013) Jenn-Wei Chen et al.   JOURNAL OF PROTEOME RESEARCH

Distortions in Development of Intestinal Microbiota Associated with Late Onset Sepsis in Preterm Infants

(2013) Volker Mai et al.   PLoS One

Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes

(2013) Aimée M. Moore et al.   PLoS One

Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs

(2013) Erica C. Pehrsson et al.   Frontiers in Microbiology

High-Throughput Sequencing Reveals the Incomplete, Short-Term Recovery of Infant Gut Microbiota following Parenteral Antibiotic Treatment with Ampicillin and Gentamicin

(2012) Fiona Fouhy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Gut microbial colonisation in premature neonates predicts neonatal sepsis

(2012) Juliette C Madan et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

(2012) L B Bindels et al.   BRITISH JOURNAL OF CANCER

Meconium microbiota types dominated by lactic acid or enteric bacteria are differentially associated with maternal eczema and respiratory problems in infants

(2012) M. J. Gosalbes et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Gut microbiota disturbance during antibiotic therapy: a multi-omic approach

(2012) Ana Elena Pérez-Cobas et al.   GUT

Antibiotics in early life alter the murine colonic microbiome and adiposity

(2012) Ilseung Cho et al.   NATURE

Antibiotics, microbiota, and immune defense

(2012) Carles Ubeda et al.   TRENDS IN IMMUNOLOGY

Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome

(2012) Ana Durbán et al.   Environmental Microbiology Reports

Acquired Antibiotic Resistance: Are We Born with It?

(2011) Lu Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

T-cell Subset Regulation in Atopy

(2011) Marek Jutel et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein-Coupled Receptor FFAR2

(2011) G. Tolhurst et al.   DIABETES

The relationship between gut microbiota and weight gain in humans

(2011) Emmanouil Angelakis et al.   Future Microbiology

Profound Alterations of Intestinal Microbiota following a Single Dose of Clindamycin Results in Sustained Susceptibility to Clostridium difficile-Induced Colitis

(2011) Charlie G. Buffie et al.   INFECTION AND IMMUNITY

Antibiotic Treatment Alters the Colonic Mucus Layer and Predisposes the Host to ExacerbatedCitrobacter rodentium-Induced Colitis

(2011) M. Wlodarska et al.   INFECTION AND IMMUNITY

Faecal Microbiota and Short-Chain Fatty Acid Levels in Faeces from Infants with Cow‘s Milk Protein Allergy

(2011) Oscar C. Thompson-Chagoyan et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics

(2011) T A Ajslev et al.   INTERNATIONAL JOURNAL OF OBESITY

Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age

(2011) Hans Bisgaard et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Low diversity of the gut microbiota in infants with atopic eczema

(2011) Thomas R. Abrahamsson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fermentation in the Human Large Intestine

(2011) George T. Macfarlane et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

The Gut as Reservoir of Antibiotic Resistance: Microbial Diversity of Tetracycline Resistance in Mother and Infant

(2011) Lisbeth E. de Vries et al.   PLoS One

Fecal Microbiota in Premature Infants Prior to Necrotizing Enterocolitis

(2011) Volker Mai et al.   PLoS One

Antibiotic Exposure by 6 Months and Asthma and Allergy at 6 Years: Findings in a Cohort of 1,401 US Children

(2010) K. R. Risnes et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Relation of early antibiotic use to childhood asthma: confounding by indication?

(2010) Y. Su et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Antibiotic use in early life and development of allergic diseases: respiratory infection as the explanation

(2010) X.-M. Mai et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Comparative Metagenomics and Population Dynamics of the Gut Microbiota in Mother and Infant

(2010) Parag A. Vaishampayan et al.   Genome Biology and Evolution

Influences of Intestinal Bacteria in Human Inflammatory Bowel Disease

(2010) Rachel Vanderploeg et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Irritable Bowel Syndrome and Small Intestinal Bacterial Overgrowth

(2010) David Yamini et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans

(2010) Carles Ubeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Postnatal Acquisition of the Intestinal Microbiome in the Early Development of Immune Function

(2010) Reed A Dimmitt et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Updated Meta-analysis of Probiotics for Preventing Necrotizing Enterocolitis in Preterm Neonates

(2010) G. Deshpande et al.   PEDIATRICS

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Vancomycin Treatment of Infective Endocarditis Is Linked with Recently Acquired Obesity

(2010) Franck Thuny et al.   PLoS One

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

(2010) L. Dethlefsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Antibiotic resistance in faecal microbiota of Greek healthy infants

(2010) E. Mitsou et al.   Beneficial Microbes

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

(2009) Charles Thomas et al.   Cell Metabolism

Altered early infant gut microbiota in children developing allergy up to 5 years of age

(2009) Y. M. Sjögren et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Influence of antibiotic exposure in the early postnatal period on the development of intestinal microbiota

(2009) Shigemitsu Tanaka et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

(2009) T. D. Lawley et al.   INFECTION AND IMMUNITY

Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies in Childhood Phase III

(2009) Sunia Foliaki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mechanisms and treatment of allergic disease in the big picture of regulatory T cells

(2009) Cezmi A. Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distribution of Tetracycline and Erythromycin Resistance Genes Among Human Oral and Fecal Metagenomic DNA

(2009) Lorna A. Seville et al.   Microbial Drug Resistance

Clostridium difficile infection: new developments in epidemiology and pathogenesis

(2009) Maja Rupnik et al.   NATURE REVIEWS MICROBIOLOGY

Antibiotic Use in Children Is Associated With Increased Risk of Asthma

(2009) F. Marra et al.   PEDIATRICS

Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora

(2009) M. O. A. Sommer et al.   SCIENCE

The association of early life exposure to antibiotics and the development of asthma, eczema and atopy in a birth cohort: confounding or causality?

(2008) K. Wickens et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The small intestinal bacterial overgrowth. Irritable bowel syndrome hypothesis: implications for treatment

(2008) S Vanner   GUT

The Biology of Intestinal Immunoglobulin A Responses

(2008) Andrea Cerutti et al.   IMMUNITY

Commensal bacteria trigger a full dendritic cell maturation program that promotes the expansion of non-Tr1 suppressor T cells

(2008) Nobuyasu Baba et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

(2008) Katharina Brandl et al.   NATURE

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Microbial Prevalence, Diversity and Abundance in Amniotic Fluid During Preterm Labor: A Molecular and Culture-Based Investigation

(2008) Daniel B. DiGiulio et al.   PLoS One

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

(2008) B. S. Samuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is meconium from healthy newborns actually sterile?

(2008) Esther Jiménez et al.   RESEARCH IN MICROBIOLOGY

Early-life exposures associated with antibiotic use and risk of subsequent Crohn's disease

(2008) Hans Hildebrand et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing

(2008) Les Dethlefsen et al.   PLOS BIOLOGY

Th17 and Allergy

(2008) Keisuke Oboki et al.   ALLERGOLOGY INTERNATIONAL

Antibiotic-Associated Diarrhea: Candidate Organisms other than Clostridium Difficile

(2008) Hyun Joo Song et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Reduced diversity in the early fecal microbiota of infants with atopic eczema

(2007) Mei Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY