Optimized design and analysis of preclinical intervention studies in vivo

A mouse’s house may ruin experiments

(2016) Sara Reardon   NATURE

Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges

(2015) Chi-Ping Day et al.   CELL

UK funders demand strong statistics for animal studies

(2015) Daniel Cressey   NATURE

Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

(2015) B. Seashore-Ludlow et al.   Cancer Discovery

The Economics of Reproducibility in Preclinical Research

(2015) Leonard P. Freedman et al.   PLOS BIOLOGY

A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

(2015) Valerie C Henderson et al.   eLife

Optimal Allocation of Prognostic Factors in Randomized Preclinical Animal Studies

(2015) Zheng Su   DRUG INFORMATION JOURNAL

Castration Induces Up-Regulation of Intratumoral Androgen Biosynthesis and Androgen Receptor Expression in an Orthotopic VCaP Human Prostate Cancer Xenograft Model

(2014) Matias Knuuttila et al.   AMERICAN JOURNAL OF PATHOLOGY

Policy: NIH plans to enhance reproducibility

(2014) Francis S. Collins et al.   NATURE

Preclinical research: Make mouse studies work

(2014) Steve Perrin   NATURE

Open Science and Reporting Animal Studies: Who's Accountable?

(2014) Jonathan A. Eisen et al.   PLOS BIOLOGY

Two Years Later: Journals Are Not Yet Enforcing the ARRIVE Guidelines on Reporting Standards for Pre-Clinical Animal Studies

(2014) David Baker et al.   PLOS BIOLOGY

Distinguishing between Exploratory and Confirmatory Preclinical Research Will Improve Translation

(2014) Jonathan Kimmelman et al.   PLOS BIOLOGY

What Have We Really Learned About Macrophage Recruitment to Adipose Tissue?

(2013) Alyssa H. Hasty et al.   ENDOCRINOLOGY

When Mice Mislead

(2013) J. Couzin-Frankel   SCIENCE

Whole Animal Experiments Should Be More Like Human Randomized Controlled Trials

(2013) Beverly S. Muhlhausler et al.   PLOS BIOLOGY

Threats to Validity in the Design and Conduct of Preclinical Efficacy Studies: A Systematic Review of Guidelines for In Vivo Animal Experiments

(2013) Valerie C. Henderson et al.   PLOS MEDICINE

Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice

(2013) Falk Hildebrand et al.   GENOME BIOLOGY

Reporting of preclinical tumor-graft cancer therapeutic studies

(2012) Elizabeth Sugar et al.   CANCER BIOLOGY & THERAPY

Improved Statistical Modeling of Tumor Growth and Treatment Effect in Preclinical Animal Studies with Highly Heterogeneous Responses In Vivo

(2012) T. D. Laajala et al.   CLINICAL CANCER RESEARCH

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

Modeling and predicting clinical efficacy for drugs targeting the tumor milieu

(2012) Mallika Singh et al.   NATURE BIOTECHNOLOGY

Optimal Nonbipartite Matching and Its Statistical Applications

(2011) Bo Lu et al.   AMERICAN STATISTICIAN

Statistical issues in the use of dynamic allocation methods for balancing baseline covariates

(2011) G R Pond   BRITISH JOURNAL OF CANCER

Why animal research needs to improve

(2011) Malcolm Macleod   NATURE

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

Bayesian Hierarchical Changepoint Methods in Modeling the Tumor Growth Profiles in Xenograft Experiments

(2010) L. Zhao et al.   CLINICAL CANCER RESEARCH

Trends in the application of dynamic allocation methods in multi-arm cancer clinical trials

(2010) Gregory R Pond et al.   Clinical Trials

IRINI: Random group allocation of multiple prognostic factors

(2010) Jyotsna Kasturi et al.   Contemporary Clinical Trials

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Distance functions for categorical and mixed variables

(2008) Brendan McCane et al.   PATTERN RECOGNITION LETTERS