A meta-analysis of threats to valid clinical inference in preclinical research of sunitinib

Reducing waste from incomplete or unusable reports of biomedical research

(2014) Paul Glasziou et al.   LANCET

Clinical development success rates for investigational drugs

(2014) Michael Hay et al.   NATURE BIOTECHNOLOGY

Budgets Up at NIH, NCI, and FDA

(2014)   Cancer Discovery

Time to do something about reproducibility

(2014) Sean J Morrison   eLife

Systematic review and meta-analysis of temozolomide in animal models of glioma: was clinical efficacy predicted?

(2013) T C Hirst et al.   BRITISH JOURNAL OF CANCER

A Proposal Regarding Reporting of In Vitro Testing Results

(2013) M. A. Smith et al.   CLINICAL CANCER RESEARCH

Six red flags for suspect work

(2013) C. Glenn Begley   NATURE

Reproducibility of research and preclinical validation: problems and solutions

(2013) Lajos Pusztai et al.   Nature Reviews Clinical Oncology

The Lambeth Conventions (II): Guidelines for the study of animal and human ventricular and supraventricular arrhythmias

(2013) Michael J. Curtis et al.   PHARMACOLOGY & THERAPEUTICS

Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases

(2013) Konstantinos K. Tsilidis et al.   PLOS BIOLOGY

Threats to Validity in the Design and Conduct of Preclinical Efficacy Studies: A Systematic Review of Guidelines for In Vivo Animal Experiments

(2013) Valerie C. Henderson et al.   PLOS MEDICINE

Reporting of preclinical tumor-graft cancer therapeutic studies

(2012) Elizabeth Sugar et al.   CANCER BIOLOGY & THERAPY

Identification of new epilepsy treatments: Issues in preclinical methodology

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

A phase II study of sunitinib in patients with relapsed or refractory small cell lung cancer

(2012) Ji-Youn Han et al.   LUNG CANCER

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

A search filter for increasing the retrieval of animal studies in Embase

(2011) Rob B M de Vries et al.   LABORATORY ANIMALS

Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors

(2011) Eric Raymond et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dopamine agonists in animal models of Parkinson’s disease: A systematic review and meta-analysis

(2011) Evelien D.M. Rooke et al.   PARKINSONISM & RELATED DISORDERS

Direct and Differential Suppression of Myeloid-Derived Suppressor Cell Subsets by Sunitinib Is Compartmentally Constrained

(2010) Jennifer S. Ko et al.   CANCER RESEARCH

Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed

(2010) Carlijn R Hooijmans et al.   LABORATORY ANIMALS

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data

(2009) Byron C Wallace et al.   BMC Medical Research Methodology

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis

(2009) Brett E. Houk et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma

(2009) Robert J. Motzer et al.   JOURNAL OF CLINICAL ONCOLOGY

Survey of the Quality of Experimental Design, Statistical Analysis and Reporting of Research Using Animals

(2009) Carol Kilkenny et al.   PLoS One

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma

(2008) S. Amarasingh et al.   JOURNAL OF NEURO-ONCOLOGY

Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program

(2008) John M. Maris et al.   PEDIATRIC BLOOD & CANCER

Empirical Evidence of Bias in the Design of Experimental Stroke Studies

(2008) Nicolas A. Crossley et al.   STROKE