Threats to Validity in the Design and Conduct of Preclinical Efficacy Studies: A Systematic Review of Guidelines for In Vivo Animal Experiments

Announcement: Reducing our irreproducibility

(2013)   NATURE

Preclinical research in Rett syndrome: setting the foundation for translational success

(2012) D. M. Katz et al.   Disease Models & Mechanisms

Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project

(2012) Katharine Briggs et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

Should preclinical studies be registered?

(2012) Jonathan Kimmelman et al.   NATURE BIOTECHNOLOGY

The translational challenge in the development of new and effective therapies for endometriosis: a review of confidence from published preclinical efficacy studies

(2011) Nick Pullen et al.   HUMAN REPRODUCTION UPDATE

Animal Research: Reporting in vivo Experiments—The ARRIVE Guidelines

(2011) Carol Kilkenny et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Believe it or not: how much can we rely on published data on potential drug targets?

(2011) Florian Prinz et al.   NATURE REVIEWS DRUG DISCOVERY

Enhancing translation: Guidelines for standard pre-clinical experiments in mdx mice

(2011) Raffaella Willmann et al.   NEUROMUSCULAR DISORDERS

Dopamine agonists in animal models of Parkinson’s disease: A systematic review and meta-analysis

(2011) Evelien D.M. Rooke et al.   PARKINSONISM & RELATED DISORDERS

Stem Cell Therapy as an Emerging Paradigm for Stroke (STEPS) II

(2011) Sean I. Savitz et al.   STROKE

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

(2011) Diana W Shineman et al.   Alzheimers Research & Therapy

Guidelines for preclinical animal research in ALS/MND: A consensus meeting

(2010) Albert C. Ludolph et al.   Amyotrophic Lateral Sclerosis

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis*

(2010) François Lamontagne et al.   CRITICAL CARE MEDICINE

Rodent Preclinical Models for Developing Novel Antiarthritic Molecules: Comparative Biology and Preferred Methods for Evaluating Efficacy

(2010) Brad Bolon et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

AGREE II: Advancing guideline development, reporting, and evaluation in health care

(2010) Melissa C. Brouwers et al.   PREVENTIVE MEDICINE

Beyond Access vs. Protection in Trials of Innovative Therapies

(2010) A. J. London et al.   SCIENCE

Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

(2010) Emily S. Sena et al.   PLOS BIOLOGY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Effects of NXY-059 in experimental stroke: an individual animal meta-analysis

(2009) PMW Bath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Combination Therapies for Traumatic Brain Injury: Prospective Considerations

(2009) Susan Margulies et al.   JOURNAL OF NEUROTRAUMA

Survey of the Quality of Experimental Design, Statistical Analysis and Reporting of Research Using Animals

(2009) Carol Kilkenny et al.   PLoS One

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Design, power, and interpretation of studies in the standard murine model of ALS

(2008) Sean Scott et al.   Amyotrophic Lateral Sclerosis

The FDA Critical Path Initiative and Its Influence on New Drug Development

(2008) Janet Woodcock et al.   Annual Review of Medicine

Drug-Eluting Stents in Preclinical Studies

(2008) Robert S. Schwartz et al.   Circulation-Cardiovascular Interventions

EQUATOR: reporting guidelines for health research

(2008) Douglas G Altman et al.   LANCET

Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project

(2008) Chris F Taylor et al.   NATURE BIOTECHNOLOGY

Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

(2008) Miranda D. Grounds et al.   NEUROBIOLOGY OF DISEASE

Animal models and the prediction of efficacy in clinical trials of analgesic drugs: A critical appraisal and call for uniform reporting standards

(2008) Andrew S.C. Rice et al.   PAIN

Empirical Evidence of Bias in the Design of Experimental Stroke Studies

(2008) Nicolas A. Crossley et al.   STROKE

S tem Cell T herapies as an E merging P aradigm in S troke (STEPS)

(2008)   STROKE

Good Laboratory Practice

(2008) Malcolm R. Macleod et al.   STROKE

Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study

(2008) Lesley Wood et al.   BMJ-British Medical Journal