The Autophagoproteasome a Novel Cell Clearing Organelle in Baseline and Stimulated Conditions

KLHL20 links the ubiquitin-proteasome system to autophagy termination

(2016) Chin-Chih Liu et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Drugging the undruggables: exploring the ubiquitin system for drug development

(2016) Xiaodong Huang et al.   CELL RESEARCH

Myocardial autophagic energy stress responses—macroautophagy, mitophagy, and glycophagy

(2015) Lea M. D. Delbridge et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cocaine-mediated microglial activation involves the ER stress-autophagy axis

(2015) Ming-Lei Guo et al.   Autophagy

mTORC1 signaling activates NRF1 to increase cellular proteasome levels

(2015) Yinan Zhang et al.   CELL CYCLE

The mammalian target of rapamycin modulates the immunoproteasome system in the heart

(2015) Hong-Mei Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Autophagy protects human brain microvascular endothelial cells against methylglyoxal-induced injuries, reproducible in a cerebral ischemic model in diabetic rats

(2015) Lili Fang et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells

(2015) Myriam Catalano et al.   Molecular Oncology

The unravelling of the ubiquitin system

(2015) Aaron Ciechanover   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

The role of ubiquitin/Nedd4-2 in the pathogenesis of mesial temporal lobe epilepsy

(2015) Liwen Wu et al.   PHYSIOLOGY & BEHAVIOR

mTOR inhibition activates overall protein degradation by the ubiquitin proteasome system as well as by autophagy

(2015) Jinghui Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines

(2015) Michael I. Koukourakis et al.   PLoS One

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

(2014) Pei Wang et al.   Autophagy

The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations

(2014) Filippo Sean Giorgi et al.   JOURNAL OF NEURAL TRANSMISSION

Autophagic-Lysosomal Inhibition Compromises Ubiquitin-Proteasome System Performance in a p62 Dependent Manner in Cardiomyocytes

(2014) Zongwen Tian et al.   PLoS One

TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain

(2014) A Pla et al.   Cell Death & Disease

Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma

(2014) K-D Chen et al.   Cell Death & Disease

Graphene Oxide Triggers Toll-Like Receptors/Autophagy Responses In Vitro and Inhibits Tumor Growth In Vivo

(2014) Guan-Yu Chen et al.   Advanced Healthcare Materials

The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution

(2014) Nico P. Dantuma et al.   Frontiers in Molecular Neuroscience

Cutting a fine figure

(2013) John Milton Lucocq et al.   Autophagy

Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells

(2013) Kristine Porter et al.   Autophagy

A novel crosstalk between two major protein degradation systems

(2013) Xiao J Wang et al.   Autophagy

Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells

(2013) Natalia Lisiak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Proteasomal and lysosomal protein degradation and heart disease

(2013) Xuejun Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The role of ubiquitin ligases in cardiac disease

(2013) Monte S. Willis et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism

(2013) G. J. Stout et al.   Molecular Systems Biology

Proteotoxicity and Cardiac Dysfunction — Alzheimer's Disease of the Heart?

(2013) Monte S. Willis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of the ubiquitin–proteasome system in brain ischemia: Friend or foe?

(2013) Margarida V. Caldeira et al.   PROGRESS IN NEUROBIOLOGY

Induction of autophagy by TOCP in differentiated human neuroblastoma cells lead to degradation of cytoskeletal components and inhibition of neurite outgrowth

(2013) Jia-Xiang Chen et al.   TOXICOLOGY

Comparative utility of LC3, p62 and TDP-43 immunohistochemistry in differentiation of inclusion body myositis from polymyositis and related inflammatory myopathies

(2013) Annie Hiniker et al.   Acta Neuropathologica Communications

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

(2012) Sylvain Ladoire et al.   Autophagy

Immunohistochemical analysis of macroautophagy

(2012) Wim Martinet et al.   Autophagy

Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide

(2012) Guan-Yu Chen et al.   BIOMATERIALS

Rapamycin inhibits the growth of glioblastoma

(2012) Antonietta Arcella et al.   BRAIN RESEARCH

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

Protein Degradation Pathways after Brain Ischemia

(2012) Pengfei Ge et al.   CURRENT DRUG TARGETS

Depletion of the Ubiquitin-binding Adaptor Molecule SQSTM1/p62 from Macrophages HarboringcftrΔF508 Mutation Improves the Delivery ofBurkholderia cenocepaciato the Autophagic Machinery

(2012) Basant A. Abdulrahman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RPN-6 determines C. elegans longevity under proteotoxic stress conditions

(2012) David Vilchez et al.   NATURE

Prion-like mechanisms in epileptogenesis

(2012) F. Orzi et al.   NEUROLOGICAL SCIENCES

E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells

(2012) Chen Hu et al.   TOXICOLOGY LETTERS

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

HIV Replication in CD4+ T Lymphocytes in the Presence and Absence of Follicular Dendritic Cells: Inhibition of Replication Mediated by  -1-Antitrypsin through Altered I B  Ubiquitination

(2011) X. Zhou et al.   JOURNAL OF IMMUNOLOGY

Transmission of prions within the gut and towards the central nervous system

(2011) Gianfranco Natale et al.   Prion

Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters

(2010) Sebastian J. Buss et al.   Autophagy

Investigating autophagy: Quantitative morphometric analysis using electron microscopy

(2010) Jamie M. Swanlund et al.   Autophagy

Ubiquitin: Same Molecule, Different Degradation Pathways

(2010) Michael J. Clague et al.   CELL

Effects of β-hydroxy-β-methylbutyrate treatment in different types of skeletal muscle of intact and septic rats

(2010) Miroslav Kovarik et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Role of Autophagy during Methamphetamine Neurotoxicity

(2009) Livia Pasquali et al.   Annals of the New York Academy of Sciences

The UPS and autophagy in chronic neurodegenerative disease: Six of one and half a dozen of the other—Or not?

(2009) Lynn Bedford et al.   Autophagy

Autophagy for the avoidance of neurodegeneration

(2009) F. Madeo et al.   GENES & DEVELOPMENT

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions

(2009) Yaping Chu et al.   NEUROBIOLOGY OF DISEASE

Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

(2009) K Zhu et al.   ONCOGENE

Does autophagy worsen or improve the survival of dopaminergic neurons?

(2009) Livia Pasquali et al.   PARKINSONISM & RELATED DISORDERS

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

(2009) Aruna D. Balgi et al.   PLoS One

Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection

(2008) Natalia B. Nedelsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Misfolding of Proteins with a Polyglutamine Expansion Is Facilitated by Proteasomal Chaperones

(2008) Erwann Rousseau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

(2008) Roberta Castino et al.   JOURNAL OF NEUROCHEMISTRY

Alpha-synuclein and autophagy as common steps in neurodegeneration

(2008) Michela Ferrucci et al.   PARKINSONISM & RELATED DISORDERS