In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant

In vitro Phase I and Phase II metabolism of α-pyrrolidinovalerophenone (α-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol

(2015) Noelia Negreira et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Simultaneous determination of 40 novel psychoactive stimulants in urine by liquid chromatography–high resolution mass spectrometry and library matching

(2015) Marta Concheiro et al.   JOURNAL OF CHROMATOGRAPHY A

Metabolism of JWH-015, JWH-098, JWH-251, and JWH-307 in silico and in vitro: a pilot study for the detection of unknown synthetic cannabinoids metabolites

(2014) Sabina Strano-Rossi et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC andα-PVT, by human liver microsome

(2014) Takahiro Takayama et al.   BIOMEDICAL CHROMATOGRAPHY

A 3-year review of new psychoactive substances in casework

(2014) Simon Elliott et al.   FORENSIC SCIENCE INTERNATIONAL

Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV)

(2014) Julie A. Marusich et al.   NEUROPHARMACOLOGY

‘Second-Generation’ Mephedrone Analogs, 4-MEC and 4-MePPP, Differentially Affect Monoamine Transporter Function

(2014) Kusumika Saha et al.   NEUROPSYCHOPHARMACOLOGY

In silico and in vitro metabolism studies support identification of designer drugs in human urine by liquid chromatography/quadrupole-time-of-flight mass spectrometry

(2013) Elli Tyrkkö et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Simultaneous quantification of 28 synthetic cathinones and metabolites in urine by liquid chromatography-high resolution mass spectrometry

(2013) Marta Concheiro et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products

(2013) Nahoko Uchiyama et al.   Forensic Toxicology

Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites

(2013) Noriaki Shima et al.   Forensic Toxicology

Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: a review of their pharmacology, acute toxicity, and metabolism

(2013) Kei Zaitsu et al.   Forensic Toxicology

Substituted Cathinone Products

(2013) Erik W. Gunderson et al.   Journal of Addiction Medicine

Analysis of Synthetic Cathinones Commonly Found in Bath Salts in Human Performance and Postmortem Toxicology: Method Development, Drug Distribution and Interpretation of Results

(2013) L. J. Marinetti et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Behavioral pharmacology of designer cathinones: A review of the preclinical literature

(2013) Ryan A. Gregg et al.   LIFE SCIENCES

Psychoactive ‘Bath Salts’: Compounds, Mechanisms and Toxicities

(2012) Kurt R Lehner et al.   NEUROPSYCHOPHARMACOLOGY

Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products

(2012) Michael H Baumann et al.   NEUROPSYCHOPHARMACOLOGY

Cathinone derivatives: A review of their chemistry, pharmacology and toxicology

(2011) John P. Kelly   Drug Testing and Analysis

The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue

(2011) Michael H Baumann et al.   NEUROPSYCHOPHARMACOLOGY

Metabolism of Designer Drugs of Abuse: An Updated Review

(2010) Markus R. Meyer et al.   CURRENT DRUG METABOLISM

Studies on the metabolism of the α-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by GC-MS

(2010) Markus R. Meyer et al.   JOURNAL OF MASS SPECTROMETRY

New designer drug α‐pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques

(2009) Christoph Sauer et al.   JOURNAL OF MASS SPECTROMETRY

An Automated Liquid Chromatography-Mass Spectrometry Process to Determine Metabolic Stability Half-Life and Intrinsic Clearance of Drug Candidates by Substrate Depletion

(2008) Colleen A. McNaney et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES