In vitro Phase I and Phase II metabolism of α-pyrrolidinovalerophenone (α-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol
出版年份 2015 全文链接
标题
In vitro Phase I and Phase II metabolism of α-pyrrolidinovalerophenone (α-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol
作者
关键词
Cathinones, Quadrupole time-of-flight mass spectrometry, In vitro metabolism, MDPV, Methedrone, α-PVP, New psychoactive substances
出版物
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 407, Issue 19, Pages 5803-5816
出版商
Springer Nature
发表日期
2015-05-26
DOI
10.1007/s00216-015-8763-6
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- 3,4-Methylenedioxypyrovalerone (MDPV) and metabolites quantification in human and rat plasma by liquid chromatography–high resolution mass spectrometry
- (2014) Sebastien Anizan et al. ANALYTICA CHIMICA ACTA
- Analysis of new designer drugs and common drugs of abuse in urine by a combined targeted and untargeted LC-HR-QTOFMS approach
- (2014) Michael Paul et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- The new drug phenomenon
- (2014) Simon D. Brandt et al. Drug Testing and Analysis
- A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: Determination of MDPV metabolites by LC–HRMS and discussion of the case
- (2014) Elisabetta Bertol et al. FORENSIC SCIENCE INTERNATIONAL
- A 3-year review of new psychoactive substances in casework
- (2014) Simon Elliott et al. FORENSIC SCIENCE INTERNATIONAL
- Analytical profiles of “legal highs” containing cathinones available in the area of Lisbon, Portugal
- (2014) Victor M.R. Zancajo et al. FORENSIC SCIENCE INTERNATIONAL
- Postmortem distribution of α-pyrrolidinovalerophenone and its metabolite in body fluids and solid tissues in a fatal poisoning case measured by LC–MS–MS with the standard addition method
- (2014) Koutaro Hasegawa et al. Forensic Toxicology
- Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone
- (2014) Hisashi Nagai et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Testing for Designer Stimulants: Metabolic Profiles of 16 Synthetic Cathinones Excreted Free in Human Urine
- (2014) Victor Uralets et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV)
- (2014) Julie A. Marusich et al. NEUROPHARMACOLOGY
- Studies on the microbial biotransformation of the novel psychoactive substance methylenedioxypyrovalerone (MDPV) in wastewater by means of liquid chromatography-high resolution mass spectrometry/mass spectrometry
- (2014) Marie Mardal et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Comprehensive analytical strategies based on high-resolution time-of-flight mass spectrometry to identify new psychoactive substances
- (2014) María Ibáñez et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- In silico and in vitro metabolism studies support identification of designer drugs in human urine by liquid chromatography/quadrupole-time-of-flight mass spectrometry
- (2013) Elli Tyrkkö et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites
- (2013) Noriaki Shima et al. Forensic Toxicology
- Recently abused synthetic cathinones, α-pyrrolidinophenone derivatives: a review of their pharmacology, acute toxicity, and metabolism
- (2013) Kei Zaitsu et al. Forensic Toxicology
- A fatal case of 3,4-methylenedioxypyrovalerone poisoning: coexistence of α-pyrrolidinobutiophenone and α-pyrrolidinovalerophenone in blood and/or hair
- (2013) Akira Namera et al. Forensic Toxicology
- Two Fatal Intoxications with the New Designer Drug Methedrone (4-Methoxymethcathinone)
- (2013) Maria Wikström et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Postmortem Tissue Distribution of MDPV Following Lethal Intoxication by "Bath Salts"
- (2013) J. F. Wyman et al. JOURNAL OF ANALYTICAL TOXICOLOGY
- Generation of metabolites by an automated online metabolism method using human liver microsomes with subsequent identification by LC-MS(n), and metabolism of 11 cathinones
- (2012) Daniel M. Mueller et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- XCMS Online: A Web-Based Platform to Process Untargeted Metabolomic Data
- (2012) Ralf Tautenhahn et al. ANALYTICAL CHEMISTRY
- In vitrometabolism studies on mephedrone and analysis of forensic cases
- (2012) Anders Just Pedersen et al. Drug Testing and Analysis
- New challenges and innovation in forensic toxicology: Focus on the “New Psychoactive Substances”
- (2012) Donata Favretto et al. JOURNAL OF CHROMATOGRAPHY A
- LC–MS/MS method for the quantitation of metabolites of eight commonly-used synthetic cannabinoids in human urine – An Australian perspective
- (2012) Andrew D. de Jager et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products
- (2012) Michael H Baumann et al. NEUROPSYCHOPHARMACOLOGY
- 3,4-Methylenedioxypyrovalerone (MDPV): Chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online
- (2011) M. Coppola et al. TOXICOLOGY LETTERS
- Identification of cathinones and other active components of ‘legal highs’ by mass spectrometric methods
- (2011) Dariusz Zuba TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry
- (2010) Markus R. Meyer et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Acyl glucuronides: the good, the bad and the ugly
- (2010) Sophie L. Regan et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Studies on the metabolism of the α-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by GC-MS
- (2010) Markus R. Meyer et al. JOURNAL OF MASS SPECTROMETRY
- Toxicological determination and in vitro metabolism of the designer drug methylenedioxypyrovalerone (MPDV) by gas chromatography/mass spectrometry and liquid chromatography/quadrupole time-of-flight mass spectrometry
- (2010) Sabina Strano-Rossi et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
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- (2009) Christoph Sauer et al. JOURNAL OF MASS SPECTROMETRY
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