标题
Smad7
gene delivery prevents muscle wasting associated with cancer cachexia in mice
作者
关键词
-
出版物
Science Translational Medicine
Volume 8, Issue 348, Pages 348ra98-348ra98
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2016-07-21
DOI
10.1126/scitranslmed.aac4976
参考文献
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- (2016) Ken Garber NATURE BIOTECHNOLOGY
- Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival
- (2015) Amelia J. Johnston et al. CELL
- Role of Activin A and Myostatin in Human Cancer Cachexia
- (2015) Audrey Loumaye et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration
- (2015) Tatiana V. Cohen et al. JOURNAL OF PHYSIOLOGY-LONDON
- A Phase 1/2a Follistatin Gene Therapy Trial for Becker Muscular Dystrophy
- (2015) Jerry R Mendell et al. MOLECULAR THERAPY
- Myostatin Gene Inactivation Prevents Skeletal Muscle Wasting in Cancer
- (2014) Y. S. Gallot et al. CANCER RESEARCH
- Myostatin Regulates Tissue Potency and Cardiac Calcium-Handling Proteins
- (2014) Melissa F. Jackson et al. ENDOCRINOLOGY
- Prevalence, incidence and clinical impact of cachexia: facts and numbers-update 2014
- (2014) Stephan von Haehling et al. Journal of Cachexia Sarcopenia and Muscle
- Role of interleukin-6 in cachexia
- (2014) Aditi A. Narsale et al. Current Opinion in Supportive and Palliative Care
- Elevated expression of activins promotes muscle wasting and cachexia
- (2013) Justin L. Chen et al. FASEB JOURNAL
- Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential
- (2013) H.Q. Han et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
- (2013) E. Lach-Trifilieff et al. MOLECULAR AND CELLULAR BIOLOGY
- Myostatin inhibitors as therapies for muscle wasting associated with cancer and other disorders
- (2013) Rosamund C. Smith et al. Current Opinion in Supportive and Palliative Care
- Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer
- (2012) G. Buchlis et al. BLOOD
- Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways
- (2012) Kenneth C.H. Fearon et al. Cell Metabolism
- A Novel Therapeutic Approach to Treating Obesity through Modulation of TGFβ Signaling
- (2012) Alan Koncarevic et al. ENDOCRINOLOGY
- Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin
- (2012) Catherine E. Winbanks et al. JOURNAL OF CELL BIOLOGY
- The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism
- (2012) Melissa F Jackson et al. JOURNAL OF ENDOCRINOLOGY
- A single ascending-dose study of muscle regulator ace-031 in healthy volunteers
- (2012) Kenneth M. Attie et al. MUSCLE & NERVE
- Understanding the mechanisms and treatment options in cancer cachexia
- (2012) Kenneth Fearon et al. Nature Reviews Clinical Oncology
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
- (2012) B. C. Bernardo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antibody-directed myostatin inhibition enhances muscle mass and function in tumor-bearing mice
- (2011) Kate T. Murphy et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
- (2011) Federico Mingozzi et al. NATURE REVIEWS GENETICS
- Serum myostatin levels and skeletal muscle wasting in chronic obstructive pulmonary disease
- (2011) Chun-Rong Ju et al. RESPIRATORY MEDICINE
- Treating cancer cachexia to treat cancer
- (2011) Se-Jin Lee et al. Skeletal Muscle
- Molecular, cellular and physiological characterization of the cancer cachexia-inducing C26 colon carcinoma in mouse
- (2010) Paola Aulino et al. BMC CANCER
- Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
- (2010) Xiaolan Zhou et al. CELL
- Genetic Deletion of Myostatin From the Heart Prevents Skeletal Muscle Atrophy in Heart Failure
- (2010) Joerg Heineke et al. CIRCULATION
- JunB transcription factor maintains skeletal muscle mass and promotes hypertrophy
- (2010) Anna Raffaello et al. JOURNAL OF CELL BIOLOGY
- Regulation of Muscle Mass by Follistatin and Activins
- (2010) Se-Jin Lee et al. MOLECULAR ENDOCRINOLOGY
- Myostatin Is Upregulated Following Stress in an Erk-Dependent Manner and Negatively Regulates Cardiomyocyte Growth in Culture and in a Mouse Model
- (2010) Lawrence T. Bish et al. PLoS One
- Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size
- (2009) Anne Ulrike Trendelenburg et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Myostatin represses physiological hypertrophy of the heart and excitation-contraction coupling
- (2009) Buel D. Rodgers et al. JOURNAL OF PHYSIOLOGY-LONDON
- Myostatin Propeptide Gene Delivery by Adeno-Associated Virus Serotype 8 Vectors Enhances Muscle Growth and Ameliorates Dystrophic Phenotypes in mdx Mice
- (2008) Chunping Qiao et al. HUMAN GENE THERAPY
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