Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration

Pharmacological inhibition of myostatin/TGF-β receptor/pSmad3 signaling rescues muscle regenerative responses in mouse model of type 1 diabetes

(2013) Jaemin Jeong et al.   ACTA PHARMACOLOGICA SINICA

Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling

(2013) María José Acuña et al.   HUMAN MOLECULAR GENETICS

Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α

(2013) Tatiana V. Cohen et al.   HUMAN MOLECULAR GENETICS

An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy

(2013) E. Lach-Trifilieff et al.   MOLECULAR AND CELLULAR BIOLOGY

Fast skeletal muscle troponin activator in the dy2J muscular dystrophy model

(2013) Jessica J. Miciak et al.   MUSCLE & NERVE

Disruption of Smad7 Promotes ANG II-Mediated Renal Inflammation and Fibrosis via Sp1-TGF-β/Smad3-NF.κB-Dependent Mechanisms in Mice

(2013) Guan-Xian Liu et al.   PLoS One

Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2

(2013) Y.-S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

(2012) Irina M. Conboy et al.   CELL CYCLE

Interference with Myostatin/ActRIIB Signaling as a Therapeutic Strategy for Duchenne Muscular Dystrophy

(2012) Helge Amthor et al.   CURRENT GENE THERAPY

Inhibition of myostatin reverses muscle fibrosis through apoptosis

(2012) Zhao Bo Li et al.   JOURNAL OF CELL SCIENCE

A single ascending-dose study of muscle regulator ace-031 in healthy volunteers

(2012) Kenneth M. Attie et al.   MUSCLE & NERVE

Myogenesis in dysferlin-deficient myoblasts is inhibited by an intrinsic inflammatory response

(2012) Tatiana V. Cohen et al.   NEUROMUSCULAR DISORDERS

Molecular, Physiological, and Motor Performance Defects in DMSXL Mice Carrying >1,000 CTG Repeats from the Human DM1 Locus

(2012) Aline Huguet et al.   PLoS Genetics

Inhibitory Smad7: Emerging Roles in Health and Disease

(2012) Marco A. Briones-Orta et al.   Current Molecular Pharmacology

Follistatin Improves Skeletal Muscle Healing after Injury and Disease through an Interaction with Muscle Regeneration, Angiogenesis, and Fibrosis

(2011) Jinhong Zhu et al.   AMERICAN JOURNAL OF PATHOLOGY

Genetic deletion of trkB.T1 increases neuromuscular function

(2011) Susan G. Dorsey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Long-Term Systemic Myostatin Inhibition via Liver-Targeted Gene Transfer in Golden Retriever Muscular Dystrophy

(2011) Lawrence T. Bish et al.   HUMAN GENE THERAPY

Role of TGF-β signaling in inherited and acquired myopathies

(2011) Tyesha N Burks et al.   Skeletal Muscle

Activin IIB receptor blockade attenuates dystrophic pathology in a mouse model of duchenne muscular dystrophy

(2010) Kevin J. Morine et al.   MUSCLE & NERVE

Characterization of Dysferlin Deficient SJL/J Mice to Assess Preclinical Drug Efficacy: Fasudil Exacerbates Muscle Disease Phenotype

(2010) Sree Rayavarapu et al.   PLoS One

Myostatin regulates fiber-type composition of skeletal muscle by regulating MEF2 and MyoD gene expression

(2009) Alex Hennebry et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Smad2 and 3 transcription factors control muscle mass in adulthood

(2009) Roberta Sartori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nuclear Function of Smad7 Promotes Myogenesis

(2009) T. Miyake et al.   MOLECULAR AND CELLULAR BIOLOGY

Direct Interaction between Myocyte Enhancer Factor 2 (MEF2) and Protein Phosphatase 1  Represses MEF2-Dependent Gene Expression

(2009) R. L. S. Perry et al.   MOLECULAR AND CELLULAR BIOLOGY

Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity

(2009) H. Amthor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates

(2009) J. Kota et al.   Science Translational Medicine

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

(2008) Kathryn R. Wagner et al.   ANNALS OF NEUROLOGY

Myostatin Propeptide Gene Delivery by Adeno-Associated Virus Serotype 8 Vectors Enhances Muscle Growth and Ameliorates Dystrophic Phenotypes in mdx Mice

(2008) Chunping Qiao et al.   HUMAN GENE THERAPY

The lamin B receptor under transcriptional control of C/EBPε is required for morphological but not functional maturation of neutrophils

(2008) Tatiana V. Cohen et al.   HUMAN MOLECULAR GENETICS

High-Resolution, Small Animal Radiation Research Platform With X-Ray Tomographic Guidance Capabilities

(2008) John Wong et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Smad7 Stabilizes β-Catenin Binding to E-cadherin Complex and Promotes Cell-Cell Adhesion

(2008) Yi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myostatin Directly Regulates Skeletal Muscle Fibrosis

(2008) Zhao Bo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

(2008) Morgan E. Carlson et al.   NATURE