Uptake and impact of natural diet-derived small RNA in invertebrates: Implications for ecology and agriculture

Sources and Functions of Extracellular Small RNAs in Human Circulation

(2016) Joëlle V. Fritz et al.   Annual Review of Nutrition

Evidence and potential in vivo functions for biofluid miRNAs: From expression profiling to functional testing

(2016) Hina Iftikhar et al.   BIOESSAYS

Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer

(2016) Mingzhen Zhang et al.   BIOMATERIALS

Nectar chemistry mediates the behavior of parasitized bees: consequences for plant fitness

(2016) Leif L. Richardson et al.   ECOLOGY

Variation in RNAi efficacy among insect species is attributable to dsRNA degradation in vivo

(2016) Kangxu Wang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The involvement of clathrin-mediated endocytosis and two Sid-1-like transmembrane proteins in double-stranded RNA uptake in the Colorado potato beetle midgut

(2016) K. Cappelle et al.   INSECT MOLECULAR BIOLOGY

Systemic RNAi in western corn rootworm, Diabrotica virgifera virgifera , does not involve transitive pathways

(2016) Huarong Li et al.   Insect Science

Genome-wide identification and functional annotation of miRNAs in anti-inflammatory plant and their cross-kingdom regulation in Homo sapiens

(2016) Ankita Sharma et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Bioinformatics Prediction and Experimental Validation of MicroRNAs Involved in Cross-Kingdom Interaction

(2016) Stefano Pirrò et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

RNAi as a management tool for the western corn rootworm,Diabrotica virgifera virgifera

(2016) Elane Fishilevich et al.   PEST MANAGEMENT SCIENCE

Oral delivery of dsRNA lipoplexes to German cockroach protects dsRNA from degradation and induces RNAi response

(2016) Yu-Hsien Lin et al.   PEST MANAGEMENT SCIENCE

Reduced stability and intracellular transport of dsRNA contribute to poor RNAi response in lepidopteran insects

(2016) Jayendra Nath Shukla et al.   RNA Biology

RNA ‘Information Warfare’ in Pathogenic and Mutualistic Interactions

(2016) Thomas Chaloner et al.   TRENDS IN PLANT SCIENCE

Anomalous uptake and circulatory characteristics of the plant-based small RNA MIR2911

(2016) Jian Yang et al.   Scientific Reports

Drosophila cells use nanotube-like structures to transfer dsRNA and RNAi machinery between cells

(2016) Margot Karlikow et al.   Scientific Reports

Detection of dietary plant-based small RNAs in animals

(2015) Jian Yang et al.   CELL RESEARCH

Small RNAs — the secret agents in the plant–pathogen interactions

(2015) Arne Weiberg et al.   CURRENT OPINION IN PLANT BIOLOGY

Mechanisms of RNA loading into exosomes

(2015) Teresa Janas et al.   FEBS LETTERS

Movement of regulatory RNA between animal cells

(2015) Antony M. Jose   GENESIS

The multi-tasking gut epithelium of insects

(2015) Jia-Hsin Huang et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells

(2015) Tovah Wolf et al.   JOURNAL OF NUTRITION

Determination of the potential bioavailability of plant microRNAs using a simulated human digestion process

(2015) Anna Philip et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The expanding world of small RNAs in plants

(2015) Filipe Borges et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ontogenetic and interspecific scaling of consumption in insects

(2015) James L. Maino et al.   OIKOS

Going mobile: Non-cell-autonomous small RNAs shape the genetic landscape of plants

(2015) Douglas E. Pyott et al.   PLANT BIOTECHNOLOGY JOURNAL

RNAi technologies in agricultural biotechnology: The Toxicology Forum 40th Annual Summer Meeting

(2015) James H. Sherman et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Negligible uptake and transfer of diet-derived pollen microRNAs in adult honey bees

(2015) Maryam Masood et al.   RNA Biology

Environmental RNAi in herbivorous insects

(2015) Sergey Ivashuta et al.   RNA

Full crop protection from an insect pest by expression of long double-stranded RNAs in plastids

(2015) Jiang Zhang et al.   SCIENCE

Dietary delivery: a new avenue for microRNA therapeutics?

(2015) Kendal D. Hirschi et al.   TRENDS IN BIOTECHNOLOGY

Food derived microRNAs

(2015) Anika E. Wagner et al.   Food & Function

E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans

(2015) Alper Akay et al.   Scientific Reports

Endocytic pathway mediates refractoriness of insect Bactrocera dorsalis to RNA interference

(2015) Xiaoxue Li et al.   Scientific Reports

The status of RNAi-based transgenic research in plant nematology

(2015) Tushar K. Dutta et al.   Frontiers in Microbiology

Biosafety research for non-target organism risk assessment of RNAi-based GE plants

(2015) Andrew F. Roberts et al.   Frontiers in Plant Science

RNA interference-mediated antiviral defense in insects

(2015) Don B Gammon et al.   Current Opinion in Insect Science

Antiviral defense mechanisms in honey bees

(2015) Laura M Brutscher et al.   Current Opinion in Insect Science

Detection of an Abundant Plant-Based Small RNA in Healthy Consumers

(2015) Jian Yang et al.   PLoS One

Testing Dose-Dependent Effects of the Nectar Alkaloid Anabasine on Trypanosome Parasite Loads in Adult Bumble Bees

(2015) Winston E. Anthony et al.   PLoS One

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Identification, functional characterization and phylogenetic analysis of double stranded RNA degrading enzymes present in the gut of the desert locust, Schistocerca gregaria

(2014) Niels Wynant et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Scavenger receptor-mediated endocytosis facilitates RNA interference in the desert locust,Schistocerca gregaria

(2014) N. Wynant et al.   INSECT MOLECULAR BIOLOGY

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DsRNA degradation in the pea aphid (Acyrthosiphon pisum) associated with lack of response in RNAi feeding and injection assay

(2014) Olivier Christiaens et al.   PEPTIDES

New wind in the sails: improving the agronomic value of crop plants through RNAi-mediated gene silencing

(2014) Aline Koch et al.   PLANT BIOTECHNOLOGY JOURNAL

A Comprehensive Genome-Wide Study on Tissue-Specific and Abiotic Stress-Specific miRNAs in Triticum aestivum

(2014) Ritu Pandey et al.   PLoS One

Establishing an In Vivo Assay System to Identify Components Involved in Environmental RNA Interference in the Western Corn Rootworm

(2014) Keita Miyata et al.   PLoS One

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

The challenge of RNAi-mediated control of hemipterans

(2014) Olivier Christiaens et al.   Current Opinion in Insect Science

The Digestive Tract ofDrosophila melanogaster

(2013) Bruno Lemaitre et al.   Annual Review of Genetics

Classification and Comparison of Small RNAs from Plants

(2013) Michael J. Axtell   Annual Review of Plant Biology

Characterization of Levels and Cellular Transfer of Circulating Lipoprotein-Bound MicroRNAs

(2013) Jasmin Wagner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

dsRNA uptake and persistence account for tissue-dependent susceptibility to RNA interference in the migratory locust,Locusta migratoria

(2013) D. Ren et al.   INSECT MOLECULAR BIOLOGY

A window onto siRNA delivery

(2013) Yuhua Wang et al.   NATURE BIOTECHNOLOGY

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

(2013) Gaurav Sahay et al.   NATURE BIOTECHNOLOGY

Lack of detectable oral bioavailability of plant microRNAs after feeding in mice

(2013) Brent Dickinson et al.   NATURE BIOTECHNOLOGY

RNA-mediated interference and reverse transcription control the persistence of RNA viruses in the insect model Drosophila

(2013) Bertsy Goic et al.   NATURE IMMUNOLOGY

Cysteine protease enhances plant-mediated bollworm RNA interference

(2013) Ying-Bo Mao et al.   PLANT MOLECULAR BIOLOGY

Non-Specific dsRNA-Mediated Antiviral Response in the Honey Bee

(2013) Michelle L. Flenniken et al.   PLoS One

Recipe for a Busy Bee: MicroRNAs in Honey Bee Caste Determination

(2013) Xiangqian Guo et al.   PLoS One

Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs

(2013) Kenneth W. Witwer et al.   RNA Biology

Ineffective delivery of diet-derived microRNAs to recipient animal organisms

(2013) Jonathan W. Snow et al.   RNA Biology

Is There Social RNA?

(2013) P. Sarkies et al.   SCIENCE

Caffeine in Floral Nectar Enhances a Pollinator's Memory of Reward

(2013) G. A. Wright et al.   SCIENCE

Self-Medication in Animals

(2013) J. C. de Roode et al.   SCIENCE

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Morphological and Molecular Characterization of Adult Midgut Compartmentalization in Drosophila

(2013) Nicolas Buchon et al.   Cell Reports

The possible impact of persistent virus infection on the function of the RNAi machinery in insects: a hypothesis

(2013) Luc Swevers et al.   Frontiers in Physiology

Gene Silencing in Crustaceans: From Basic Research to Biotechnologies

(2013) Amir Sagi et al.   Genes

Optimizing illumina next-generation sequencing library preparation for extremely at-biased genomes

(2012) Samuel O Oyola et al.   BMC GENOMICS

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

SID-5 Is an Endosome-Associated Protein Required for Efficient Systemic RNAi in C. elegans

(2012) Andrea Hinas et al.   CURRENT BIOLOGY

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

Defining a new role of GW182 in maintaining miRNA stability

(2012) Bing Yao et al.   EMBO REPORTS

An insect trypsin-like serine protease as a target of microRNA: Utilization of microRNA mimics and inhibitors by oral feeding

(2012) Balachandran Jayachandran et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bombyx mori DNA/RNA non-specific nuclease: Expression of isoforms in insect culture cells, subcellular localization and functional assays

(2012) Jisheng Liu et al.   JOURNAL OF INSECT PHYSIOLOGY

Persistence of double-stranded RNA in insect hemolymph as a potential determiner of RNA interference success: Evidence from Manduca sexta and Blattella germanica

(2012) Jennie S. Garbutt et al.   JOURNAL OF INSECT PHYSIOLOGY

Uptake of Extracellular Double-Stranded RNA by SID-2

(2012) Deborah L. McEwan et al.   MOLECULAR CELL

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Intrinsic antiviral immunity

(2012) Nan Yan et al.   NATURE IMMUNOLOGY

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

(2012) Gavriel Mullokandov et al.   NATURE METHODS

Intercellular communication: diverse structures for exchange of genetic information

(2012) Maria Mittelbrunn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evolution of Susceptibility to Ingested Double-Stranded RNAs in Caenorhabditis Nematodes

(2012) Isabelle Nuez et al.   PLoS One

Epigenetic Modification of Gene Expression in Honey Bees by Heterospecific Gland Secretions

(2012) Yuan Yuan Shi et al.   PLoS One

Characterizing the Mechanism of Action of Double-Stranded RNA Activity against Western Corn Rootworm (Diabrotica virgifera virgifera LeConte)

(2012) Renata Bolognesi et al.   PLoS One

The Complex Exogenous RNA Spectra in Human Plasma: An Interface with Human Gut Biota?

(2012) Kai Wang et al.   PLoS One

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

(2012) M. Rera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

XenomiRs and miRNA homeostasis in health and disease

(2012) Kenneth W. Witwer   RNA Biology

The SID-1 double-stranded RNA transporter is not required for systemic RNAi in the migratory locust

(2012) Yuan Luo et al.   RNA Biology

Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma

(2012) Andrey Turchinovich et al.   RNA Biology

New foods for thought

(2012) Kendal D. Hirschi   TRENDS IN PLANT SCIENCE

Escherichia coli noncoding RNAs can affect gene expression and physiology of Caenorhabditis elegans

(2012) Huijie Liu et al.   Nature Communications

Vampiric Isolation of Extracellular Fluid from Caenorhabditis elegans

(2012) Stephen A. Banse et al.   Jove-Journal of Visualized Experiments

Ecological Physiology of Diet and Digestive Systems

(2011) William H. Karasov et al.   Annual Review of Physiology

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

(2011) Lin Zhang et al.   CELL RESEARCH

Homo sapiensSystemic RNA Interference-defective-1 Transmembrane Family Member 1 (SIDT1) Protein Mediates Contact-dependent Small RNA Transfer and MicroRNA-21-driven Chemoresistance

(2011) Mohamed O. Elhassan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Saliva of Lygus lineolaris digests double stranded ribonucleic acids

(2011) Margaret L. Allen et al.   JOURNAL OF INSECT PHYSIOLOGY

Integrative Regulatory Mapping Indicates that the RNA-Binding Protein HuR Couples Pre-mRNA Processing and mRNA Stability

(2011) Neelanjan Mukherjee et al.   MOLECULAR CELL

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Scavenger Receptor Mediates Systemic RNA Interference in Ticks

(2011) Kyaw Min Aung et al.   PLoS One

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SID-1 is a dsRNA-selective dsRNA-gated channel

(2011) J. D. Shih et al.   RNA

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Why Worry about How Many Species and Their Loss?

(2011) Robert M. May   PLOS BIOLOGY

Modifications of Small RNAs and Their Associated Proteins

(2010) Young-Kook Kim et al.   CELL

Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid and powdered milk products

(2010) Xi Chen et al.   CELL RESEARCH

Robust MicroRNA Stability in Degraded RNA Preparations from Human Tissue and Cell Samples

(2010) M. Jung et al.   CLINICAL CHEMISTRY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

RNA interference in Lepidoptera: An overview of successful and unsuccessful studies and implications for experimental design

(2010) Olle Terenius et al.   JOURNAL OF INSECT PHYSIOLOGY

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila

(2010) Arabinda Nayak et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gut Microbiota in Health and Disease

(2010) Inna Sekirov et al.   PHYSIOLOGICAL REVIEWS

Functional delivery of viral miRNAs via exosomes

(2010) D. M. Pegtel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Non-cell-autonomous effects of vector-expressed regulatory RNAs in mammalian heart cells

(2009) E Kizana et al.   GENE THERAPY

Ingested double-stranded RNAs can act as species-specific insecticides

(2009) Steven Whyard et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: A review

(2009) Hanneke Huvenne et al.   JOURNAL OF INSECT PHYSIOLOGY

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

(2009) Derrick J. Gibbings et al.   NATURE CELL BIOLOGY

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

(2009) Brian D. Brown et al.   NATURE REVIEWS GENETICS

Developmental Control of a Lepidopteran Pest Spodoptera exigua by Ingestion of Bacteria Expressing dsRNA of a Non-Midgut Gene

(2009) Honggang Tian et al.   PLoS One

The SID-1 double-stranded RNA transporter is not selective for dsRNA length

(2009) J. D. Shih et al.   RNA

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

(2009) A. Zernecke et al.   Science Signaling

Field Experiments with Transformed Plants Reveal the Sense of Floral Scents

(2008) D. Kessler et al.   SCIENCE

Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium

(2008) Yoshinori Tomoyasu et al.   GENOME BIOLOGY