Single-molecule imaging reveals a common mechanism shared by G-quadruplex–resolving helicases

Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites

(2015) A. Piazza et al.   EMBO JOURNAL

G4-associated human diseases

(2015) N. Maizels   EMBO REPORTS

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

(2015) William C. Drosopoulos et al.   JOURNAL OF CELL BIOLOGY

ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity

(2015) Jagat B. Budhathoki et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence

(2015) Alex Kreig et al.   NUCLEIC ACIDS RESEARCH

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase

(2015) Michael C. Chen et al.   NUCLEIC ACIDS RESEARCH

BLM unfolds G-quadruplexes in different structural environments through different mechanisms

(2015) Wen-Qiang Wu et al.   NUCLEIC ACIDS RESEARCH

Insights into G-quadruplex specific recognition by the DEAH-box helicase RHAU: Solution structure of a peptide–quadruplex complex

(2015) Brahim Heddi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation

(2015) X Gao et al.   Cell Death & Disease

The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events

(2015) Deanna N. Edwards et al.   Nature Communications

Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers

(2015) Bennie Lemmens et al.   Nature Communications

DNA and RNA Quadruplex-Binding Proteins

(2014) Václav Brázda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

G-quadruplex conformation and dynamics are determined by loop length and sequence

(2014) Ramreddy Tippana et al.   NUCLEIC ACIDS RESEARCH

Repetitive RNA unwinding by RNA helicase A facilitates RNA annealing

(2014) Hye Ran Koh et al.   NUCLEIC ACIDS RESEARCH

RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

(2014) Jagat B. Budhathoki et al.   NUCLEIC ACIDS RESEARCH

Telomeric Overhang Length Determines Structural Dynamics and Accessibility to Telomerase and ALT-Associated Proteins

(2014) Helen Hwang et al.   STRUCTURE

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

(2014) Sujoy Chatterjee et al.   Nature Communications

Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA

(2014) Ruobo Zhou et al.   eLife

Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

(2013) Sanjay Kumar Bharti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Loops and G-Quartets on the Stability of RNA G-Quadruplexes

(2013) Satyaprakash Pandey et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Srs2 prevents Rad51 filament formation by repetitive motion on DNA

(2013) Yupeng Qiu et al.   Nature Communications

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

(2012) Rama Rao Damerla et al.   CELL CYCLE

Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design

(2011) Jixun Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA

(2011) Banabihari Giri et al.   NUCLEIC ACIDS RESEARCH

c-MYC promoter G-quadruplex formed at the 5′-end of NHE III 1 element: insights into biological relevance and parallel-stranded G-quadruplex stability

(2011) Raveendra I. Mathad et al.   NUCLEIC ACIDS RESEARCH

PcrA Helicase Dismantles RecA Filaments by Reeling in DNA in Uniform Steps

(2010) Jeehae Park et al.   CELL

Processing of human telomeres by the Werner syndrome protein

(2010) Sita Reddy et al.   CELL CYCLE

Mechanisms of trinucleotide repeat instability during human development

(2010) Cynthia T. McMurray   NATURE REVIEWS GENETICS

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

(2009) Jaya G Yodh et al.   EMBO JOURNAL

G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic

(2009) Prakrit V. Jena et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Werner Syndrome Helicase/Exonuclease Processes Mobile D-Loops through Branch Migration and Degradation

(2009) Patricia L. Opresko et al.   PLoS One

Cytosolic Viral Sensor RIG-I Is a 5'-Triphosphate-Dependent Translocase on Double-Stranded RNA

(2009) S. Myong et al.   SCIENCE

G4 Resolvase 1 Binds Both DNA and RNA Tetramolecular Quadruplex with High Affinity and Is the Major Source of Tetramolecular Quadruplex G4-DNA and G4-RNA Resolving Activity in HeLa Cell Lysates

(2008) Steven D. Creacy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS