Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

Human RecQ Helicases in DNA Repair, Recombination, and Replication

(2014) Deborah L. Croteau et al.   Annual Review of Biochemistry

Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2

(2014) Deanna N. Edwards et al.   NUCLEIC ACIDS RESEARCH

RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

(2014) Jagat B. Budhathoki et al.   NUCLEIC ACIDS RESEARCH

Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

(2014) Giang Huong Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding

(2014) S. Ray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

(2013) Giang Huong Nguyen et al.   CHEMISTRY & BIOLOGY

Neisseria gonorrhoeae RecQ Helicase HRDC Domains Are Essential for Efficient Binding and Unwinding of the pilE Guanine Quartet Structure Required for Pilin Antigenic Variation

(2013) L. A. Cahoon et al.   JOURNAL OF BACTERIOLOGY

Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

(2013) Sanjay Kumar Bharti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genomes and G-Quadruplexes: For Better or for Worse

(2013) Madalena Tarsounas et al.   JOURNAL OF MOLECULAR BIOLOGY

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Fork sensing and strand switching control antagonistic activities of RecQ helicases

(2013) Daniel Klaue et al.   Nature Communications

Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

(2012) Raphaël Rodriguez et al.   Nature Chemical Biology

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics

(2012) Helen Hwang et al.   STRUCTURE

The Werner and Bloom Syndrome Proteins Help Resolve Replication Blockage by Converting (Regressed) Holliday Junctions to Functional Replication Forks

(2011) Amrita Machwe et al.   BIOCHEMISTRY

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

(2011) Avvaru N Suhasini et al.   EMBO JOURNAL

G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase

(2011) Q. Wang et al.   NUCLEIC ACIDS RESEARCH

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA

(2011) Peter Sarkies et al.   NUCLEIC ACIDS RESEARCH

Unwinding the functions of the Pif1 family helicases

(2010) Matthew L. Bochman et al.   DNA REPAIR

G-quadruplex nucleic acids and human disease

(2010) Yuliang Wu et al.   FEBS Journal

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

High-throughput production of human proteins for crystallization: The SGC experience

(2010) Pavel Savitsky et al.   JOURNAL OF STRUCTURAL BIOLOGY

G-Quadruplex Hinders Translocation of BLM Helicase on DNA: A Real-Time Fluorescence Spectroscopic Unwinding Study and Comparison with Duplex Substrates

(2010) Jia-quan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and function of the regulatory HRDC domain from human Bloom syndrome protein

(2010) Young Mee Kim et al.   NUCLEIC ACIDS RESEARCH

Insight into helicase mechanism and function revealed through single-molecule approaches

(2010) Jaya G. Yodh et al.   QUARTERLY REVIEWS OF BIOPHYSICS

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

(2009) Jaya G Yodh et al.   EMBO JOURNAL

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

(2009) Jay E. Johnson et al.   NUCLEIC ACIDS RESEARCH

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

(2008) Yong Qin et al.   BIOCHIMIE

FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

(2008) Timothy B. C. London et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

(2008) Kai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase  

(2008) N. Selak et al.   NUCLEIC ACIDS RESEARCH