Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

(2016) Rika Kusumoto-Matsuo et al.   Aging-US

Telomere sister chromatid exchange and the process of aging

(2016) Krastan B. Blagoev et al.   Aging-US

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

Non-B DNA-forming Sequences and WRN Deficiency Independently Increase the Frequency of Base Substitution in Human Cells

(2011) Albino Bacolla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest

(2010) Julia M. Sidorova et al.   CELL CYCLE

Telomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability

(2010) Rama Rao Damerla et al.   DNA REPAIR

Single Molecule Studies of Physiologically Relevant Telomeric Tails Reveal POT1 Mechanism for Promoting G-quadruplex Unfolding

(2010) Hong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Folding Pathways of Human Telomeric Type-1 and Type-2 G-Quadruplex Structures

(2010) Tomoko Mashimo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Werner Syndrome Protein Suppresses Telomeric Instability Caused by Chromium (VI) Induced DNA Replication Stress

(2010) Fu-Jun Liu et al.   PLoS One

Hyper telomere recombination accelerates replicative senescence and may promote premature aging

(2010) R. T. Hagelstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomeres and telomerase in cancer

(2009) S. E. Artandi et al.   CARCINOGENESIS

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

TERRA: telomeric repeat-containing RNA

(2009) Brian Luke et al.   EMBO JOURNAL

Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN

(2009) N. Arnoult et al.   GENES & DEVELOPMENT

Large-Scale Expansions of Friedreich's Ataxia GAA Repeats in Yeast

(2009) Alexander A. Shishkin et al.   MOLECULAR CELL

DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D

(2009) Sandeep N. Shah et al.   NUCLEIC ACIDS RESEARCH

Direct visualization of G-quadruplexes in DNA using atomic force microscopy

(2009) Kelly J. Neaves et al.   NUCLEIC ACIDS RESEARCH

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

(2009) Angela Rizzo et al.   NUCLEIC ACIDS RESEARCH

The Werner Syndrome Helicase/Exonuclease Processes Mobile D-Loops through Branch Migration and Degradation

(2009) Patricia L. Opresko et al.   PLoS One

The Werner Syndrome Protein Functions in Repair of Cr(VI)-Induced Replication-Associated DNA Damage

(2009) Fu-Jun Liu et al.   TOXICOLOGICAL SCIENCES

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Werner syndrome helicase activity is essential in maintaining fragile site stability

(2008) Livia Maria Pirzio et al.   JOURNAL OF CELL BIOLOGY

WRN Is Required for ATM Activation and the S-Phase Checkpoint in Response to Interstrand Cross-Link–Induced DNA Double-Strand Breaks

(2008) Wen-Hsing Cheng et al.   MOLECULAR BIOLOGY OF THE CELL

Discovery of alternative DNA structures: a heroic decade (1979-1989)

(2007) Sergei et al.   Frontiers in Bioscience-Landmark