G-quadruplex conformation and dynamics are determined by loop length and sequence

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

(2014) Aaron R. Haeusler et al.   NATURE

G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD

(2014) Lucas T Gray et al.   Nature Chemical Biology

G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding

(2014) S. Ray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Loop Sequence and Loop Length on the Intrinsic Fluorescence of G-Quadruplexes

(2013) Chun Kit Kwok et al.   BIOCHEMISTRY

RPA-Mediated Unfolding of Systematically Varying G-Quadruplex Structures

(2013) Sujay Ray et al.   BIOPHYSICAL JOURNAL

High-Resolution Insight into G-Overhang Architecture

(2013) Robert Hänsel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Long-Loop G-Quadruplexes Are Misfolded Population Minorities with Fast Transition Kinetics in Human Telomeric Sequences

(2013) Deepak Koirala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and mechanical properties of individual human telomeric G-quadruplexes in molecularly crowded solutions

(2013) Soma Dhakal et al.   NUCLEIC ACIDS RESEARCH

Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy

(2013) Xi Long et al.   NUCLEIC ACIDS RESEARCH

Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity

(2013) Kah Wai Lim et al.   NUCLEIC ACIDS RESEARCH

Kinetic Partitioning Modulates Human Telomere DNA G-Quadruplex Structural Polymorphism

(2013) Xi Long et al.   PLoS One

G-quadruplex structures are stable and detectable in human genomic DNA

(2013) Enid Yi Ni Lam et al.   Nature Communications

Conformations of individual quadruplex units studied in the context of extended human telomeric DNA

(2012) Vijay Singh et al.   CHEMICAL COMMUNICATIONS

DNA secondary structures: stability and function of G-quadruplex structures

(2012) Matthew L. Bochman et al.   NATURE REVIEWS GENETICS

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interaction of human telomeric DNA with N- methyl mesoporphyrin IX

(2012) John M. Nicoludis et al.   NUCLEIC ACIDS RESEARCH

Insight into G-DNA Structural Polymorphism and Folding from Sequence and Loop Connectivity through Free Energy Analysis

(2011) Xiaohui Cang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design

(2011) Jixun Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of Human Telomeric DNA in Crowded Solution

(2011) Brahim Heddi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA

(2011) Banabihari Giri et al.   NUCLEIC ACIDS RESEARCH

c-MYC promoter G-quadruplex formed at the 5′-end of NHE III 1 element: insights into biological relevance and parallel-stranded G-quadruplex stability

(2011) Raveendra I. Mathad et al.   NUCLEIC ACIDS RESEARCH

Structure, location and interactions of G-quadruplexes

(2010) Julian L. Huppert   FEBS Journal

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter

(2010) Vitaly Kuryavyi et al.   NUCLEIC ACIDS RESEARCH

G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic

(2009) Prakrit V. Jena et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dramatic effect of single-base mutation on the conformational dynamics of human telomeric G-quadruplex

(2009) Ja Yil Lee et al.   NUCLEIC ACIDS RESEARCH

G4 Resolvase 1 Binds Both DNA and RNA Tetramolecular Quadruplex with High Affinity and Is the Major Source of Tetramolecular Quadruplex G4-DNA and G4-RNA Resolving Activity in HeLa Cell Lysates

(2008) Steven D. Creacy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS

Mix and measure fluorescence screening for selective quadruplex binders

(2008) Sattanathan Paramasivan et al.   NUCLEIC ACIDS RESEARCH

A Sequence-Independent Study of the Influence of Short Loop Lengths on the Stability and Topology of Intramolecular DNA G-Quadruplexes†

(2007) Anthony Bugaut et al.   BIOCHEMISTRY