标题
Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target
作者
关键词
-
出版物
PARASITOLOGY
Volume 145, Issue 02, Pages 116-133
出版商
Cambridge University Press (CUP)
发表日期
2016-12-15
DOI
10.1017/s0031182016002377
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Fluorescence-based assay for polyprenyl phosphate-GlcNAc-1-phosphate transferase (WecA) and identification of novel antimycobacterial WecA inhibitors
- (2016) Katsuhiko Mitachi et al. ANALYTICAL BIOCHEMISTRY
- UDP-GlcNAc pathway: Potential target for inhibitor discovery against M. tuberculosis
- (2016) Chitra Rani et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis
- (2016) Sandeep Thanna et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Identification of KasA as the cellular target of an anti-tubercular scaffold
- (2016) Katherine A. Abrahams et al. Nature Communications
- Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor
- (2016) María Martínez-Hoyos et al. EBioMedicine
- The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis
- (2015) Vadim Makarov et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection
- (2015) Joaquín Rullas et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis
- (2015) Gaëlle S. Kolly et al. JOURNAL OF BACTERIOLOGY
- Lead selection and characterization of antitubercular compounds using the Nested Chemical Library
- (2015) Anna Sipos et al. TUBERCULOSIS
- Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase
- (2015) Sarah M. Batt et al. ACS Infectious Diseases
- Mycobacterial Dihydrofolate Reductase Inhibitors Identified Using Chemogenomic Methods and In Vitro Validation
- (2015) Grace Mugumbate et al. PLoS One
- Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F
- (2014) Martina Hrast et al. BIOORGANIC CHEMISTRY
- Towards a new combination therapy for tuberculosis with next generation benzothiazinones
- (2014) V. Makarov et al. EMBO Molecular Medicine
- Discovery of a capuramycin analog that kills nonreplicating Mycobacterium tuberculosis and its synergistic effects with translocase I inhibitors
- (2014) Shajila Siricilla et al. JOURNAL OF ANTIBIOTICS
- Specificity of the Transport of Lipid II by FtsW inEscherichia coli
- (2014) Tamimount Mohammadi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA
- (2014) Lourdes Encinas et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, Synthesis, and Evaluation of New Thiadiazole-Based Direct Inhibitors of Enoyl Acyl Carrier Protein Reductase (InhA) for the Treatment of Tuberculosis
- (2014) Roman Šink et al. JOURNAL OF MEDICINAL CHEMISTRY
- Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway inMycobacterium tuberculosisusing conditional mutants
- (2014) Gaëlle S. Kolly et al. MOLECULAR MICROBIOLOGY
- Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target
- (2014) Sudagar S. Gurcha et al. PLoS One
- MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis
- (2014) L.-T. Sham et al. SCIENCE
- Covalent Modification of the Mycobacterium tuberculosis FAS-II Dehydratase by Isoxyl and Thiacetazone
- (2014) Anna E. Grzegorzewicz et al. ACS Infectious Diseases
- Kinetic mechanism and inhibition ofMycobacterium tuberculosisd-alanine:d-alanine ligase by the antibioticd-cycloserine
- (2013) Gareth A. Prosser et al. FEBS Journal
- Inhibition of the First Step in Synthesis of the Mycobacterial Cell Wall Core, Catalyzed by the GlcNAc-1-phosphate Transferase WecA, by the Novel Caprazamycin Derivative CPZEN-45
- (2013) Yoshimasa Ishizaki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis
- (2013) Regina Wilson et al. Nature Chemical Biology
- Inhibition studies on Mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU)
- (2013) Anh Thu Tran et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Identification of Novel Imidazo[1,2-a]pyridine Inhibitors Targeting M. tuberculosis QcrB
- (2013) Katherine A. Abrahams et al. PLoS One
- Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis
- (2013) Tulika Munshi et al. PLoS One
- Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tuberculosis Targeting MmpL3
- (2013) Modesto J. Remuiñán et al. PLoS One
- Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis
- (2013) Thomas R. Ioerger et al. PLoS One
- Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32
- (2013) S. A. Stanley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in Mycobacterium tuberculosis
- (2013) Gareth A. Prosser et al. ACS Medicinal Chemistry Letters
- Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening
- (2012) Sarah A. Stanley et al. ACS Chemical Biology
- SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis
- (2012) Kapil Tahlan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antigen 85C Inhibition Restricts Mycobacterium tuberculosis Growth through Disruption of Cord Factor Biosynthesis
- (2012) Thulasi Warrier et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inactivation of Mycobacterium tuberculosis l,d-Transpeptidase LdtMt1by Carbapenems and Cephalosporins
- (2012) Vincent Dubée et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis
- (2012) Karthik Raman et al. BMC Systems Biology
- MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria
- (2012) Cristian Varela et al. CHEMISTRY & BIOLOGY
- Targeting InhA, the FASII Enoyl-ACP Reductase: SAR Studies on Novel Inhibitor Scaffolds
- (2012) Pan Pan et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
- (2012) Katherine A Sacksteder et al. Future Microbiology
- The Galactosamine Residue in Mycobacterial Arabinogalactan Is α-Linked
- (2012) Wenjie Peng et al. JOURNAL OF ORGANIC CHEMISTRY
- Meropenem inhibits D,D-carboxypeptidase activity inMycobacterium tuberculosis
- (2012) Pradeep Kumar et al. MOLECULAR MICROBIOLOGY
- Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane
- (2012) Anna E Grzegorzewicz et al. Nature Chemical Biology
- Ppm1-Encoded Polyprenyl Monophosphomannose Synthase Activity Is Essential for Lipoglycan Synthesis and Survival in Mycobacteria
- (2012) Amrita K. Rana et al. PLoS One
- Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors
- (2012) S. M. Batt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reconstitution of Functional Mycobacterial Arabinosyltransferase AftC Proteoliposome and Assessment of Decaprenylphosphorylarabinose Analogues as Arabinofuranosyl Donors
- (2011) Jian Zhang et al. ACS Chemical Biology
- MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212
- (2011) Valentina La Rosa et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Novel Inhibitors of InhA Efficiently KillMycobacterium tuberculosisunder Aerobic and Anaerobic Conditions
- (2011) Catherine Vilchèze et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Design and synthesis of novel cell wall inhibitors of Mycobacterium tuberculosis GlmM and GlmU
- (2011) Yongmeng Li et al. CARBOHYDRATE RESEARCH
- Identification of FtsW as a transporter of lipid-linked cell wall precursors across the membrane
- (2011) Tamimount Mohammadi et al. EMBO JOURNAL
- nvestigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster
- (2011) P. Dianišková et al. GENERAL PHYSIOLOGY AND BIOPHYSICS
- ESI-MS Assay of M. tuberculosis Cell Wall Antigen 85 Enzymes Permits Substrate Profiling and Design of a Mechanism-Based Inhibitor
- (2011) Conor S. Barry et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The effect of MSMEG_6402 gene disruption on the cell wall structure of Mycobacterium smegmatis
- (2011) Tao Jiang et al. MICROBIAL PATHOGENESIS
- Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching
- (2011) Arun K. Mishra et al. MOLECULAR MICROBIOLOGY
- The C-Terminal Domain of the Arabinosyltransferase Mycobacterium tuberculosis EmbC Is a Lectin-Like Carbohydrate Binding Module
- (2011) Luke J. Alderwick et al. PLoS Pathogens
- Structure of theMycobacterium tuberculosisd-Alanine:d-Alanine Ligase, a Target of the Antituberculosis Drug d-Cycloserine
- (2010) John B. Bruning et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics
- (2010) Amy E. Trunkfield et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthetic UDP-Furanoses as Potent Inhibitors of Mycobacterial Galactan Biogenesis
- (2010) Pauline Peltier et al. CHEMISTRY & BIOLOGY
- Mycobacterium tuberculosis Rv1302 and Mycobacterium smegmatis MSMEG___4947 have WecA function and MSMEG__4947 is required for the growth of M. smegmatis
- (2010) Yue Jin et al. FEMS MICROBIOLOGY LETTERS
- Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase
- (2010) L. J. Alderwick et al. GLYCOBIOLOGY
- Redundant Function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis Cyclopropanation of Oxygenated Mycolates
- (2010) D. Barkan et al. JOURNAL OF BACTERIOLOGY
- Biosynthetic Origin of the Galactosamine Substituent of Arabinogalactan inMycobacterium tuberculosis
- (2010) Henrieta Škovierová et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques
- (2010) Vivek Kumar et al. JOURNAL OF MOLECULAR MODELING
- A truncated lipoglycan from mycobacteria with altered immunological properties
- (2010) H. L. Birch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and function of GlmU fromMycobacterium tuberculosis
- (2009) Zhening Zhang et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Activity of SQ641, a Capuramycin Analog, in a Murine Model of Tuberculosis
- (2009) B. V. Nikonenko et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- 5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases
- (2009) Tihomir Tomašić et al. ChemMedChem
- AftD, a novel essential arabinofuranosyltransferase from mycobacteria
- (2009) Henrieta Škovierová et al. GLYCOBIOLOGY
- Identification of a Polyprenylphosphomannosyl Synthase Involved in the Synthesis of Mycobacterial Mannosides
- (2009) H. Scherman et al. JOURNAL OF BACTERIOLOGY
- New Insights into the Early Steps of Phosphatidylinositol Mannoside Biosynthesis in Mycobacteria
- (2009) Marcelo E. Guerin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The mycolyltransferase 85A, a putative drug target of Mycobacterium tuberculosis: Development of a novel assay and quantification of glycolipid-status of the mycobacterial cell wall
- (2009) Ayssar A. Elamin et al. JOURNAL OF MICROBIOLOGICAL METHODS
- Epimeric and amino disaccharide analogs as probes of an α-(1→6)-mannosyltransferase involved in mycobacterial lipoarabinomannanbiosynthesis
- (2009) Pui Hang Tam et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases
- (2009) Alistair K. Brown et al. PLoS One
- Meropenem-Clavulanate Is Effective Against Extensively Drug-Resistant Mycobacterium tuberculosis
- (2009) J.-E. Hugonnet et al. SCIENCE
- High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors
- (2009) Thierry Christophe et al. PLoS Pathogens
- Synthesis of methyl 5-S-alkyl-5-thio-d-arabinofuranosides and evaluation of their antimycobacterial activity
- (2008) Aditya K. Sanki et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors
- (2008) Mamoun M. Alhamadsheh et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Loss of a Mycobacterial Gene Encoding a Reductase Leads to an Altered Cell Wall Containing β-oxo- Mycolic Acid Analogs and Accumulation of Ketones
- (2008) Apoorva Bhatt et al. CHEMISTRY & BIOLOGY
- Antigen 85C-mediated acyl-transfer between synthetic acyl donors and fragments of the arabinan
- (2008) Aditya K. Sanki et al. GLYCOCONJUGATE JOURNAL
- Mutations in pimE Restore Lipoarabinomannan Synthesis and Growth in a Mycobacterium smegmatis lpqW Mutant
- (2008) P. K. Crellin et al. JOURNAL OF BACTERIOLOGY
- The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by L,D-Transpeptidation
- (2008) M. Lavollay et al. JOURNAL OF BACTERIOLOGY
- The Identification and Location of Succinyl Residues and the Characterization of the Interior Arabinan Region Allow for a Model of the Complete Primary Structure ofMycobacterium tuberculosisMycolyl Arabinogalactan
- (2008) Suresh Bhamidi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development of a microtitre plate-based assay for lipid-linked glycosyltransferase products using the mycobacterial cell wall rhamnosyltransferase WbbL
- (2008) A. E. Grzegorzewicz et al. MICROBIOLOGY-SGM
- Identification of amino acids and domains required for catalytic activity of DPPR synthase, a cell wall biosynthetic enzyme of Mycobacterium tuberculosis
- (2008) H. Huang et al. MICROBIOLOGY-SGM
- Identification of a novel α(1→6) mannopyranosyltransferase MptB fromCorynebacterium glutamicumby deletion of a conserved gene,NCgl1505, affords a lipomannan- and lipoarabinomannan-deficient mutant
- (2008) Arun K. Mishra et al. MOLECULAR MICROBIOLOGY
- Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli
- (2008) N. Ruiz PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lipoarabinomannan of Mycobacterium: Mannose capping by a multifunctional terminal mannosyltransferase
- (2008) D. Kaur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression, purification and characterisation of soluble GlfT and the identification of a novel galactofuranosyltransferase Rv3782 involved in priming GlfT-mediated galactan polymerisation in Mycobacterium tuberculosis
- (2007) Luke J. Alderwick et al. PROTEIN EXPRESSION AND PURIFICATION
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