Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway inMycobacterium tuberculosisusing conditional mutants

Advances in the development of new tuberculosis drugs and treatment regimens

(2013) Alimuddin Zumla et al.   NATURE REVIEWS DRUG DISCOVERY

Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole-Cell Screening

(2012) Garth L. Abrahams et al.   CHEMISTRY & BIOLOGY

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

(2012) E. Fullam et al.   Open Biology

New tuberculosis drugs on the horizon

(2011) Stewart T Cole et al.   CURRENT OPINION IN MICROBIOLOGY

Decaprenylphosphoryl-β-D-Ribose 2′-Epimerase, the Target of Benzothiazinones and Dinitrobenzamides, Is an Essential Enzyme in Mycobacterium smegmatis

(2011) Paul K. Crellin et al.   PLoS One

Depletion of antibiotic targets has widely varying effects on growth

(2011) J.-R. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Simple Model for Testing Drugs against Nonreplicating Mycobacterium tuberculosis

(2010) C. Sala et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase

(2010) L. J. Alderwick et al.   GLYCOBIOLOGY

Development of a repressible mycobacterial promoter system based on two transcriptional repressors

(2010) Francesca Boldrin et al.   NUCLEIC ACIDS RESEARCH

Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis

(2010) Anna P. Lucarelli et al.   PLoS One

Leads for antitubercular compounds from kinase inhibitor library screens

(2010) Sophie Magnet et al.   TUBERCULOSIS

TubercuList – 10 years after

(2010) Jocelyne M. Lew et al.   TUBERCULOSIS

Application of Fragment Growing and Fragment Linking to the Discovery of Inhibitors ofMycobacterium tuberculosisPantothenate Synthetase

(2009) Alvin W. Hung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

(2009) V. Makarov et al.   SCIENCE

High Content Screening Identifies Decaprenyl-Phosphoribose 2′ Epimerase as a Target for Intracellular Antimycobacterial Inhibitors

(2009) Thierry Christophe et al.   PLoS Pathogens

Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy

(2008) Beata A. Wolucka   FEBS Journal

The Structural Basis of Chain Length Control in Rv1086

(2008) Wenjian Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

d-Ribose-5-Phosphate Isomerase B from Escherichia coli is Also a Functional d-Allose-6-Phosphate Isomerase, While the Mycobacterium tuberculosis Enzyme is Not

(2008) Annette K. Roos et al.   JOURNAL OF MOLECULAR BIOLOGY

Partial redundancy in the synthesis of the D-arabinose incorporated in the cell wall arabinan of Corynebacterineae

(2008) X. Meniche et al.   MICROBIOLOGY-SGM