Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis

SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis

(2012) Kapil Tahlan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identifying Vulnerable Pathways in Mycobacterium tuberculosis by Using a Knockdown Approach

(2011) Paul Carroll et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis inMycobacterium tuberculosis

(2011) Jessica C. Seeliger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel 1,2,3-Triazole Derivatives for Use againstMycobacterium tuberculosisH37Rv (ATCC 27294) Strain

(2011) Nubia Boechat et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos

(2011) Laeticia Alibaud et al.   MOLECULAR MICROBIOLOGY

Depletion of antibiotic targets has widely varying effects on growth

(2011) J.-R. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vitro Interactions between New Antitubercular Drug Candidates SQ109 and TMC207

(2010) V. M. Reddy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Enzymatic Hydrolysis of Trehalose Dimycolate Releases Free Mycolic Acids during Mycobacterial Growth in Biofilms

(2010) Anil K. Ojha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of theMycobacterium tuberculosisβ-Ketoacyl-Acyl Carrier Protein Reductase MabA Regulates Mycolic Acid Biosynthesis

(2010) Romain Veyron-Churlet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

(2010) José A Caminero et al.   LANCET INFECTIOUS DISEASES

How antibiotics kill bacteria: from targets to networks

(2010) Michael A. Kohanski et al.   NATURE REVIEWS MICROBIOLOGY

β-Lactam and glycopeptide antibiotics: first and last line of defense?

(2010) Srdjan Jovetic et al.   TRENDS IN BIOTECHNOLOGY

The Dual Function of the Mycobacterium tuberculosis FadD32 Required for Mycolic Acid Biosynthesis

(2009) Mathieu Léger et al.   CHEMISTRY & BIOLOGY

Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosis

(2009) Joel S. Freundlich et al.   ChemMedChem

The Pks13/FadD32 Crosstalk for the Biosynthesis of Mycolic Acids inMycobacterium tuberculosis

(2009) Sabine Gavalda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships

(2009) Pilho Kim et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rapid and spontaneous loss of phthiocerol dimycocerosate (PDIM) from Mycobacterium tuberculosis grown in vitro: implications for virulence studies

(2009) P. Domenech et al.   MICROBIOLOGY-SGM

Antituberculosis activity of the molecular libraries screening center network library

(2009) Joseph A. Maddry et al.   TUBERCULOSIS

High-throughput screening for inhibitors of Mycobacterium tuberculosis H37Rv

(2009) Subramaniam Ananthan et al.   TUBERCULOSIS

Transfer of embB Codon 306 Mutations into Clinical Mycobacterium tuberculosis Strains Alters Susceptibility to Ethambutol, Isoniazid, and Rifampin

(2008) H. Safi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY