标题
The Nrf2/HO-1 Axis in Cancer Cell Growth and Chemoresistance
作者
关键词
-
出版物
Oxidative Medicine and Cellular Longevity
Volume 2016, Issue -, Pages 1-14
出版商
Hindawi Limited
发表日期
2015-12-01
DOI
10.1155/2016/1958174
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation
- (2016) Stefan W. Ryter et al. Translational Research
- ZnPPIX inhibits peritoneal metastasis of gastric cancer via its antiangiogenic activity
- (2015) Fu-tai Shang et al. BIOMEDICINE & PHARMACOTHERAPY
- Discovery of oxime-bearing naphthalene derivatives as a novel structural type of Nrf2 activators
- (2015) Ken-Ming Chang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Roles of Nrf2 in cell proliferation and differentiation
- (2015) Shohei Murakami et al. FREE RADICAL BIOLOGY AND MEDICINE
- Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2
- (2015) Adedamola Olayanju et al. FREE RADICAL BIOLOGY AND MEDICINE
- Dual roles of NRF2 in tumor prevention and progression: Possible implications in cancer treatment
- (2015) Eui Jung Moon et al. FREE RADICAL BIOLOGY AND MEDICINE
- Induction of Heme Oxygenase-1 by Na+-H+Exchanger 1 Protein Plays a Crucial Role in Imatinib-resistant Chronic Myeloid Leukemia Cells
- (2015) Dan Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Luteolin modulates expression of drug-metabolizing enzymes through the AhR and Nrf2 pathways in hepatic cells
- (2014) Tianshun Zhang et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Luteolin Sensitizes Two Oxaliplatin-Resistant Colorectal Cancer Cell Lines to Chemotherapeutic Drugs Via Inhibition of the Nrf2 Pathway
- (2014) Song Chian et al. Asian Pacific Journal of Cancer Prevention
- Luteolin inhibits the Nrf2 signaling pathway and tumor growth in vivo
- (2014) Song Chian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- HO-1 up-regulation: A key point in high-risk neuroblastoma resistance to bortezomib
- (2014) Anna Lisa Furfaro et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Nrf2, the master redox switch: The Achilles' heel of ovarian cancer?
- (2014) Monique G.P. van der Wijst et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity
- (2014) Hongzhuan Yin et al. BMC CANCER
- Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells
- (2014) M Valenzuela et al. BRITISH JOURNAL OF CANCER
- Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2
- (2014) S. Tao et al. CANCER RESEARCH
- Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways
- (2014) Bhupendra Singh et al. CARCINOGENESIS
- Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis
- (2014) T. Wu et al. GENES & DEVELOPMENT
- Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer
- (2014) Victor D. Martinez et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy?
- (2014) Tongde Wu et al. MOLECULAR CARCINOGENESIS
- Imine Resveratrol Analogues: Molecular Design, Nrf2 Activation and SAR Analysis
- (2014) Chang Li et al. PLoS One
- The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Cytoprotection “gone astray’’: Nrf2 and its role in cancer
- (2014) Heiner Schafer et al. OncoTargets and Therapy
- Unique Pattern of Component Gene Disruption in the NRF2 Inhibitor KEAP1/CUL3/RBX1 E3-Ubiquitin Ligase Complex in Serous Ovarian Cancer
- (2014) Victor D. Martinez et al. Biomed Research International
- Heme Oxygenase-1: A Metabolic Nike
- (2013) Barbara Wegiel et al. ANTIOXIDANTS & REDOX SIGNALING
- Differential response of DU145 and PC3 prostate cancer cells to ionizing radiation: Role of reactive oxygen species, GSH and Nrf2 in radiosensitivity
- (2013) Sundarraj Jayakumar et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Nrf2 is required to maintain the self-renewal of glioma stem cells
- (2013) Jianhong Zhu et al. BMC CANCER
- Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling
- (2013) L-H Wang et al. BRITISH JOURNAL OF CANCER
- CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
- (2013) A. Ooi et al. CANCER RESEARCH
- Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination
- (2013) B. E. Hast et al. CANCER RESEARCH
- RXR Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2
- (2013) H. Wang et al. CANCER RESEARCH
- Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells
- (2013) Che-Yi Chao et al. CARCINOGENESIS
- Blockage of Nrf2 suppresses the migration and invasion of esophageal squamous cell carcinoma cells in hypoxic microenvironment
- (2013) H. Shen et al. DISEASES OF THE ESOPHAGUS
- Oncogenic potential of Nrf2 and its principal target protein heme oxygenase-1
- (2013) Hye-Kyung Na et al. FREE RADICAL BIOLOGY AND MEDICINE
- The emerging role of the Nrf2-Keap1 signaling pathway in cancer
- (2013) M. C. Jaramillo et al. GENES & DEVELOPMENT
- Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels
- (2013) T. Suzuki et al. MOLECULAR AND CELLULAR BIOLOGY
- Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer
- (2013) Victor D Martinez et al. Molecular Cancer
- Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
- (2013) Yoshinobu Ichimura et al. MOLECULAR CELL
- Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases
- (2013) Hemant Kumar et al. NATURAL PRODUCT REPORTS
- Nrf2 regulates haematopoietic stem cell function
- (2013) Jennifer J. Tsai et al. NATURE CELL BIOLOGY
- Role of Glutathione in Cancer Progression and Chemoresistance
- (2013) Nicola Traverso et al. Oxidative Medicine and Cellular Longevity
- A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways
- (2013) Fei-Fei Gan et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways
- (2013) Minh Truong Do et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Identification of aldo-keto reductases as NRF2-target marker genes in human cells
- (2013) Kyeong-Ah Jung et al. TOXICOLOGY LETTERS
- Differential Nrf2 expression between glioma stem cells and non-stem-like cells in glioblastoma
- (2013) JIANHONG ZHU et al. Oncology Letters
- Smad7 sensitizes A549 lung cancer cells to cisplatin-induced apoptosis through heme oxygenase-1 inhibition
- (2012) Woo-Kwang Jeon et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation
- (2012) Holly K. Bryan et al. BIOCHEMICAL PHARMACOLOGY
- Methylation of the KEAP1 gene promoter region in human colorectal cancer
- (2012) Naoyuki Hanada et al. BMC CANCER
- Bortezomib induces heme oxygenase-1 expression in multiple myeloma
- (2012) Lawrence N. Barrera et al. CELL CYCLE
- Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response
- (2012) Jennifer Paek et al. Cell Metabolism
- Metformin Use Is Associated with Better Survival of Diabetic Patients with Pancreatic Cancer
- (2012) N. Sadeghi et al. CLINICAL CANCER RESEARCH
- Heme Oxygenase-1 in Tumor Biology and Therapy
- (2012) Halina Was et al. CURRENT DRUG TARGETS
- HSP32 (HO-1) inhibitor, copoly(styrene-maleic acid)-zinc protoporphyrin IX, a water-soluble micelle as anticancer agent: In vitro and in vivo anticancer effect
- (2012) Jun Fang et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Expression and function of heme oxygenase-1 in human gastric cancer
- (2012) Yujing Yin et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- The transcription factor NF-E2-related Factor 2 (Nrf2): a protooncogene?
- (2012) Phillip Shelton et al. FASEB JOURNAL
- An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses
- (2012) Saelooom Lee et al. FREE RADICAL BIOLOGY AND MEDICINE
- Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
- (2012) Kai Takaya et al. FREE RADICAL BIOLOGY AND MEDICINE
- Wilms Tumor Gene on X Chromosome (WTX) Inhibits Degradation of NRF2 Protein through Competitive Binding to KEAP1 Protein
- (2012) Nathan D. Camp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells
- (2012) W. D. Kim et al. JOURNAL OF CELL SCIENCE
- Micelles of zinc protoporphyrin conjugated to N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer for imaging and light-induced antitumor effects in vivo
- (2012) Hideaki Nakamura et al. JOURNAL OF CONTROLLED RELEASE
- Expression of heme oxygenase-1 in non-small cell lung cancer (NSCLC) and its correlation with clinical data
- (2012) María S. Degese et al. LUNG CANCER
- Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents
- (2012) Sadagopan Magesh et al. MEDICINAL RESEARCH REVIEWS
- PALB2 Interacts with KEAP1 To Promote NRF2 Nuclear Accumulation and Function
- (2012) J. Ma et al. MOLECULAR AND CELLULAR BIOLOGY
- Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response
- (2012) Yan Zhong et al. MOLECULAR CARCINOGENESIS
- Synthetic Condensed 1,4-naphthoquinone Derivative Shifts Neural Stem Cell Differentiation by Regulating Redox State
- (2012) Daniela M. Santos et al. MOLECULAR NEUROBIOLOGY
- Osteopontin increases heme oxygenase–1 expression and subsequently induces cell migration and invasion in glioma cells
- (2012) Dah-Yuu Lu et al. NEURO-ONCOLOGY
- Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha
- (2012) B. N. Chorley et al. NUCLEIC ACIDS RESEARCH
- Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks
- (2012) Yosuke Hirotsu et al. NUCLEIC ACIDS RESEARCH
- The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains
- (2012) J-H Kim et al. ONCOGENE
- Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
- (2012) S Chowdhry et al. ONCOGENE
- Keap1 degradation by autophagy for the maintenance of redox homeostasis
- (2012) K. Taguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cadmium-induced apoptosis in the BJAB human B cell line: Involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression
- (2012) Saïd Nemmiche et al. TOXICOLOGY
- High expression of heme oxygenase-1 is associated with tumor invasiveness and poor clinical outcome in non-small cell lung cancer patients
- (2012) Jong-Rung Tsai et al. CELLULAR ONCOLOGY
- The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism
- (2012) Yoichiro Mitsuishi et al. Frontiers in Oncology
- Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer
- (2011) M. Ferrando et al. ANGIOGENESIS
- Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy
- (2011) Subash C. Gupta et al. ANTIOXIDANTS & REDOX SIGNALING
- Transcription factor Nrf2 maintains the basal expression of Mdm2: An implication of the regulation of p53 signaling by Nrf2
- (2011) Aram You et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Nrf2: control of sensitivity to carcinogens
- (2011) Stephen L. Slocum et al. ARCHIVES OF TOXICOLOGY
- Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles
- (2011) Abena S. Agyeman et al. BREAST CANCER RESEARCH AND TREATMENT
- Inhibition of Heme Oxygenase-1 Enhances the Radiosensitivity in Human Nonsmall Cell Lung Cancer A549 Cells
- (2011) Wenyi Zhang et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1
- (2011) T.-H. Kim et al. CANCER RESEARCH
- Frequent epigenetics inactivation of KEAP1 gene in non-small cell lung cancer
- (2011) Lucia Anna Muscarella et al. Epigenetics
- Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs
- (2011) Xiuwen Tang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1
- (2011) Anna Lisa Furfaro et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
- (2011) Keiko Taguchi et al. GENES TO CELLS
- The Heme Oxygenase-1 Protein Is Overexpressed in Human Renal Cancer Cells following Activation of the Ras-Raf-ERK Pathway and Mediates Anti-Apoptotic Signal
- (2011) Pallavi Banerjee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner
- (2011) P. Rada et al. MOLECULAR AND CELLULAR BIOLOGY
- Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
- (2011) Gina M. DeNicola et al. NATURE
- Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
- (2011) D. Ren et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of NF-E2-Related Factor 2 Signaling for Cancer Chemoprevention: Antioxidant Coupled with Antiinflammatory
- (2010) Rong Hu et al. ANTIOXIDANTS & REDOX SIGNALING
- Chemistry of the Cysteine Sensors in Kelch-Like ECH-Associated Protein 1
- (2010) Ryan Holland et al. ANTIOXIDANTS & REDOX SIGNALING
- Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview
- (2010) Ken Itoh et al. ANTIOXIDANTS & REDOX SIGNALING
- Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene
- (2010) Lisa Becks et al. BMC CANCER
- Nrf2–ARE signaling pathway and natural products for cancer chemoprevention
- (2010) Cui Rong Zhao et al. Cancer Epidemiology
- Global Downstream Pathway Analysis Reveals a Dependence of Oncogenic NF-E2-Related Factor 2 Mutation on the mTOR Growth Signaling Pathway
- (2010) T. Shibata et al. CANCER RESEARCH
- NF-κB–Inhibited Acute Myeloid Leukemia Cells Are Rescued from Apoptosis by Heme Oxygenase-1 Induction
- (2010) Stuart A. Rushworth et al. CANCER RESEARCH
- High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer
- (2010) T. Jiang et al. CANCER RESEARCH
- Nrf2 and p21 regulate the fine balance between life and death by controlling ROS levels
- (2010) Nicole F. Villeneuve et al. CELL CYCLE
- Keap1-Nrf2 activation in the presence and absence of DJ-1
- (2010) Li Gan et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway
- (2010) Ian M. Copple et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
- (2010) Ashish Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Correlation of Nrf2, HO-1, and MRP3 in Gallbladder Cancer and Their Relationships to Clinicopathologic Features and Survival
- (2010) Jiansheng Wang et al. JOURNAL OF SURGICAL RESEARCH
- Expression of ABCG2 (BCRP) Is Regulated by Nrf2 in Cancer Cells That Confers Side Population and Chemoresistance Phenotype
- (2010) Anju Singh et al. MOLECULAR CANCER THERAPEUTICS
- Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth
- (2010) P. Zhang et al. MOLECULAR CANCER THERAPEUTICS
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
- (2010) Deepti Malhotra et al. NUCLEIC ACIDS RESEARCH
- Regulation of Notch1 Signaling by Nrf2: Implications for Tissue Regeneration
- (2010) N. Wakabayashi et al. Science Signaling
- Clinical Significance of Heme Oxygenase-1 Expression in Non-Muscle-Invasive Bladder Cancer
- (2010) Makito Miyake et al. UROLOGIA INTERNATIONALIS
- A Novel Experimental Heme Oxygenase-1-Targeted Therapy for Hormone-Refractory Prostate Cancer
- (2009) M. A. Alaoui-Jamali et al. CANCER RESEARCH
- Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds
- (2009) A.Kenneth MacLeod et al. CARCINOGENESIS
- Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice
- (2009) Melinda S. Yates et al. CARCINOGENESIS
- Reactive oxygen species-dependent signaling regulates cancer
- (2009) Frank Weinberg et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Δ12,14-prostaglandin J2 requires Nrf2
- (2009) Simona Bancos et al. CELLULAR IMMUNOLOGY
- Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer
- (2009) S. Homma et al. CLINICAL CANCER RESEARCH
- Multidrug-resistant protein-3 gene regulation by the transcription factor Nrf2 in human bronchial epithelial and non-small-cell lung carcinoma
- (2009) Christopher M. Mahaffey et al. FREE RADICAL BIOLOGY AND MEDICINE
- Acquisition of doxorubicin resistance in ovarian carcinoma cells accompanies activation of the NRF2 pathway
- (2009) Gi-seong Shim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo
- (2009) Philipp Nuhn et al. Molecular Cancer
- Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy
- (2009) M. Loignon et al. MOLECULAR CANCER THERAPEUTICS
- Direct Interaction between Nrf2 and p21Cip1/WAF1 Upregulates the Nrf2-Mediated Antioxidant Response
- (2009) Weimin Chen et al. MOLECULAR CELL
- NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer
- (2009) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- Heme Oxygenase-1 and the Vascular Bed: From Molecular Mechanisms to Therapeutic Opportunities
- (2008) Agnieszka Loboda et al. ANTIOXIDANTS & REDOX SIGNALING
- Increased Susceptibility of Nrf2 Knockout Mice to Colitis-Associated Colorectal Cancer
- (2008) T. O. Khor et al. Cancer Prevention Research
- DNA repair and cancer stem-like cells – Potential partners in glioma drug resistance?
- (2008) Tor-Christian Aase Johannessen et al. CANCER TREATMENT REVIEWS
- Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[ a ]pyrene-treated mice: mechanism of its anti-initiating action
- (2008) Rachana Garg et al. CARCINOGENESIS
- Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2
- (2008) X.-J. Wang et al. CARCINOGENESIS
- Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice
- (2008) Gabriele Sass et al. INTERNATIONAL JOURNAL OF CANCER
- Upregulation of Heme Oxygenase-1 Expression in Areca-quid-chewing-associated Oral Squamous Cell Carcinoma
- (2008) Shiuan-Shinn Lee et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Dibenzoylmethane Activates Nrf2-Dependent Detoxification Pathway and Inhibits Benzo(a)pyrene Induced DNA Adducts in Lungs
- (2008) R. Thimmulappa et al. Medicinal Chemistry
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity
- (2008) T. Yamamoto et al. MOLECULAR AND CELLULAR BIOLOGY
- The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds
- (2008) M. Kobayashi et al. MOLECULAR AND CELLULAR BIOLOGY
- Dual roles of Nrf2 in cancer
- (2008) A LAU et al. PHARMACOLOGICAL RESEARCH
- Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
- (2008) T. Shibata et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults
- (2007) W OSBURN et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started