Regulatory Nexus of Synthesis and Degradation Deciphers Cellular Nrf2 Expression Levels

NRF2 Mutation Confers Malignant Potential and Resistance to Chemoradiation Therapy in Advanced Esophageal Squamous Cancer

(2015) Tatsuhiro Shibata et al.   NEOPLASIA

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers

(2012) T Yamadori et al.   ONCOGENE

Polymorphisms in the transcription factor NRF2 and forearm vasodilator responses in humans

(2012) Ewa D. Marczak et al.   Pharmacogenetics and Genomics

An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study

(2011) Hironori Masuko et al.   BMC Medical Genetics

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

Jun and JunD-dependent functions in cell proliferation and stress response

(2010) A Meixner et al.   CELL DEATH AND DIFFERENTIATION

Effect of NFE2L2 Genetic Polymorphism on the Association Between Oral Estrogen Therapy and the Risk of Venous Thromboembolism in Postmenopausal Women

(2010) J Bouligand et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Phase I Metabolic Genes and Risk of Lung Cancer: Multiple Polymorphisms and mRNA Expression

(2009) Melissa Rotunno et al.   PLoS One

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

(2009) Larry G. Higgins et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

(2008) Masaru Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements

(2008) Atsushi Maruyama et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

(2008) A. Singh et al.   CANCER RESEARCH

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Common 5p15.33 and 6p21.33 variants influence lung cancer risk

(2008) Yufei Wang et al.   NATURE GENETICS

Lung cancer susceptibility locus at 5p15.33

(2008) James D McKay et al.   NATURE GENETICS

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA