Review: Sporadic Parkinson's disease: development and distribution ofα-synuclein pathology
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标题
Review: Sporadic Parkinson's disease: development and distribution ofα-synuclein pathology
作者
关键词
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出版物
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
Volume 42, Issue 1, Pages 33-50
出版商
Wiley
发表日期
2015-12-13
DOI
10.1111/nan.12298
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies
- (2015) Toshiki Uchihara et al. ACTA NEUROPATHOLOGICA
- α-synuclein pathology accumulates in sacral spinal visceral sensory pathways
- (2015) Veronique G. VanderHorst et al. ANNALS OF NEUROLOGY
- Vagotomy and subsequent risk of Parkinson's disease
- (2015) Elisabeth Svensson et al. ANNALS OF NEUROLOGY
- The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease
- (2015) Heiko Braak et al. BRAIN
- Alteration of Upstream Autophagy-Related Proteins (ULK1, ULK2, Beclin1, VPS34 and AMBRA1) in Lewy Body Disease
- (2015) Yasuo Miki et al. BRAIN PATHOLOGY
- Alpha-Synuclein Pathology in Sensory Nerve Terminals of the Upper Aerodigestive Tract of Parkinson’s Disease Patients
- (2015) Liancai Mu et al. DYSPHAGIA
- Correlation Between Structural and Functional Retinal Changes in Parkinson Disease
- (2015) Manpreet Kaur et al. JOURNAL OF NEURO-OPHTHALMOLOGY
- Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations
- (2015) Benjamin Dehay et al. LANCET NEUROLOGY
- Crystals of a toxic core
- (2015) Michel Goedert et al. NATURE
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
- (2015) W. Peelaerts et al. NATURE
- Structure of the toxic core of α-synuclein from invisible crystals
- (2015) Jose A. Rodriguez et al. NATURE
- Spreading of α-synuclein in the face of axonal transport deficits in Parkinson's disease: A speculative synthesis
- (2015) Jennifer T. Lamberts et al. NEUROBIOLOGY OF DISEASE
- α-Synuclein pathology in the cranial and spinal nerves in Lewy body disease
- (2015) Keiko Nakamura et al. NEUROPATHOLOGY
- Alpha-synuclein immunoreactivity patterns in the enteric nervous system
- (2015) Iban Aldecoa et al. NEUROSCIENCE LETTERS
- Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled A , tau, and -synuclein
- (2015) M. Goedert SCIENCE
- Parkinson's disease as a member of Prion-like disorders
- (2015) Maria Eugenia Herva et al. VIRUS RESEARCH
- Viral capsid assembly as a model for protein aggregation diseases: Active processes catalyzed by cellular assembly machines comprising novel drug targets
- (2015) Rita Marreiros et al. VIRUS RESEARCH
- Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
- (2015) Ulf Dettmer et al. Nature Communications
- Role of Different Alpha-Synuclein Strains in Synucleinopathies, Similarities with other Neurodegenerative Diseases
- (2015) Ronald Melki Journal of Parkinsons Disease
- Distribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons
- (2015) Hiroyuki Sumikura et al. Acta Neuropathologica Communications
- Alpha-synuclein in peripheral tissues and body fluids as a biomarker for Parkinson's disease - a systematic review
- (2014) N. Malek et al. ACTA NEUROLOGICA SCANDINAVICA
- Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
- (2014) Staffan Holmqvist et al. ACTA NEUROPATHOLOGICA
- Cutaneous neuropathy in Parkinson’s disease: a window into brain pathology
- (2014) Kathrin Doppler et al. ACTA NEUROPATHOLOGICA
- Preventing α-synuclein aggregation: The role of the small heat-shock molecular chaperone proteins
- (2014) Dezerae Cox et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Prion-like Mechanisms in the Pathogenesis of Tauopathies and Synucleinopathies
- (2014) Michel Goedert et al. Current Neurology and Neuroscience Reports
- Mortality in Parkinson's disease: A 38-year follow-up study
- (2014) Bernadette Pinter et al. MOVEMENT DISORDERS
- Intramuscular injection of -synuclein induces CNS -synuclein pathology and a rapid-onset motor phenotype in transgenic mice
- (2014) A. N. Sacino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alpha-synuclein spreading in Parkinson’s disease
- (2014) Ariadna Recasens et al. Frontiers in Neuroanatomy
- Alpha-synuclein biology in Lewy body diseases
- (2014) Woojin Scott Kim et al. Alzheimers Research & Therapy
- α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration
- (2014) Hien T. Tran et al. Cell Reports
- Considerations on the role of environmental toxins in idiopathic Parkinson’s disease pathophysiology
- (2014) Francisco Pan-Montojo et al. Translational Neurodegeneration
- Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson’s disease
- (2013) David Hilton et al. ACTA NEUROPATHOLOGICA
- Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice
- (2013) Nolwen L. Rey et al. ACTA NEUROPATHOLOGICA
- Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
- (2013) Ariadna Recasens et al. ANNALS OF NEUROLOGY
- α-Synuclein: The Long Distance Runner
- (2013) Sonia George et al. BRAIN PATHOLOGY
- Atypical parkinsonism
- (2013) Maria Stamelou et al. CURRENT OPINION IN NEUROLOGY
- Caudo-rostral brain spreading of α-synuclein through vagal connections
- (2013) Ayse Ulusoy et al. EMBO Molecular Medicine
- Idiopathic REM sleep behaviour disorder in the development of Parkinson's disease
- (2013) Bradley F Boeve LANCET NEUROLOGY
- Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?
- (2013) C. Warren Olanow et al. MOVEMENT DISORDERS
- Properties of native brain α-synuclein
- (2013) Jacqueline Burré et al. NATURE
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- Defining the Native State of α-Synuclein
- (2013) Dennis Selkoe et al. Neurodegenerative Diseases
- The spectrum of nonmotor symptoms in early Parkinson disease
- (2013) T. K. Khoo et al. NEUROLOGY
- Dietary fat intake, pesticide use, and Parkinson's disease
- (2013) Freya Kamel et al. PARKINSONISM & RELATED DISORDERS
- Modeling Lewy pathology propagation in Parkinson's disease
- (2013) Kelvin C. Luk et al. PARKINSONISM & RELATED DISORDERS
- Viruses and neurodegeneration
- (2013) Li Zhou et al. Virology Journal
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- The Role of Autophagy in Parkinson's Disease
- (2013) M. A. Lynch-Day et al. Cold Spring Harbor Perspectives in Medicine
- Spinal cord lesions in sporadic Parkinson’s disease
- (2012) Kelly Del Tredici et al. ACTA NEUROPATHOLOGICA
- Neuropathologic substrates of Parkinson disease dementia
- (2012) David J. Irwin et al. ANNALS OF NEUROLOGY
- Fibrillar α-Synuclein and Huntingtin Exon 1 Assemblies Are Toxic to the Cells
- (2012) Laura Pieri et al. BIOPHYSICAL JOURNAL
- Critical Role of Truncated α-Synuclein and Aggregates in Parkinson's Disease and Incidental Lewy Body Disease
- (2012) Kavita Prasad et al. BRAIN PATHOLOGY
- Evaluation of the Braak hypothesis: how far can it explain the pathogenesis of Parkinson's disease?
- (2012) Glenda Halliday et al. Expert Review of Neurotherapeutics
- α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, andEscherichia coliExists Predominantly as Disordered Monomer
- (2012) Bruno Fauvet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting the Chameleon: a Focused Look at α-Synuclein and Its Roles in Neurodegeneration
- (2012) Blanca A. Silva et al. MOLECULAR NEUROBIOLOGY
- Molecular Chaperones, Alpha-Synuclein, and Neurodegeneration
- (2012) Stephan N. Witt MOLECULAR NEUROBIOLOGY
- Infectious Agents and Neurodegeneration
- (2012) Giovanna De Chiara et al. MOLECULAR NEUROBIOLOGY
- The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders
- (2012) Koichi Wakabayashi et al. MOLECULAR NEUROBIOLOGY
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- Lewy pathology and neurodegeneration in premotor Parkinson's disease
- (2012) Kelly Del Tredici et al. MOVEMENT DISORDERS
- Identifying prodromal Parkinson's disease: Pre-Motor disorders in Parkinson's disease
- (2012) Ronald B. Postuma et al. MOVEMENT DISORDERS
- The significance of defining preclinical or prodromal Parkinson's disease
- (2012) C. Warren Olanow et al. MOVEMENT DISORDERS
- Olfactory dysfunction in Parkinson disease
- (2012) Richard L. Doty Nature Reviews Neurology
- 100 years of Lewy pathology
- (2012) Michel Goedert et al. Nature Reviews Neurology
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system
- (2012) Ali Reza Noorian et al. NEUROBIOLOGY OF DISEASE
- Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease
- (2012) J. M. Milber et al. NEUROLOGY
- Alpha-synuclein aggregates in epicardial fat tissue in living subjects without parkinsonism
- (2012) Judith Navarro-Otano et al. PARKINSONISM & RELATED DISORDERS
- Beyond α-synuclein transfer: pathology propagation in Parkinson's disease
- (2012) Christian Hansen et al. TRENDS IN MOLECULAR MEDICINE
- Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice
- (2012) Francisco Pan-Montojo et al. Scientific Reports
- Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology?
- (2012) Amanda N Sacino et al. Alzheimers Research & Therapy
- Neuropathology underlying clinical variability in patients with synucleinopathies
- (2011) Glenda M. Halliday et al. ACTA NEUROPATHOLOGICA
- α-Synuclein misfolding and Parkinson's disease
- (2011) Leonid Breydo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pale Neurites, Premature α-Synuclein Aggregates with Centripetal Extension from Axon Collaterals
- (2011) Toshiro Kanazawa et al. BRAIN PATHOLOGY
- A deadly spread: cellular mechanisms of α-synuclein transfer
- (2011) J A Steiner et al. CELL DEATH AND DIFFERENTIATION
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Dementia in Parkinson's disease: a 20-year neuropsychological study (Sydney Multicentre Study)
- (2011) W. G. J. Reid et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- View point: Etiology in Parkinson's disease. Dual hit or spreading intoxication
- (2011) Heinz Reichmann JOURNAL OF THE NEUROLOGICAL SCIENCES
- Autonomic involvement in Parkinson's disease: Pathology, pathophysiology, clinical features and possible peripheral biomarkers
- (2011) Maria G. Cersosimo et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- A critical appraisal of the premotor symptoms of Parkinson's disease: Potential usefulness in early diagnosis and design of neuroprotective trials
- (2011) Anthony E. Lang MOVEMENT DISORDERS
- Milestones in Parkinson's disease-Clinical and pathologic features
- (2011) Glenda Halliday et al. MOVEMENT DISORDERS
- Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease
- (2011) Kathleen M. Shannon et al. MOVEMENT DISORDERS
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Lewy body-related α-synucleinopathy in the spinal cord of cases with incidental Lewy body disease
- (2011) Takuya Tamura et al. NEUROPATHOLOGY
- Unmyelinated axons are more vulnerable to degeneration than myelinated axons of the cardiac nerve in Parkinson's disease
- (2011) S. Orimo et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Patterns of alpha-synuclein pathology in incidental cases and clinical subtypes of Parkinson's disease
- (2011) Wilma D.J. van de Berg et al. PARKINSONISM & RELATED DISORDERS
- Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease
- (2011) Christopher B. Forsyth et al. PLoS One
- Can Parkinson's disease pathology be propagated from one neuron to another?
- (2011) Christopher J.R. Dunning et al. PROGRESS IN NEUROBIOLOGY
- Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies
- (2010) Brittany N. Dugger et al. ACTA NEUROPATHOLOGICA
- Multi-organ distribution of phosphorylated α-synuclein histopathology in subjects with Lewy body disorders
- (2010) Thomas G. Beach et al. ACTA NEUROPATHOLOGICA
- Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson’s disease
- (2010) Kelly Del Tredici et al. ACTA NEUROPATHOLOGICA
- Proteinase K-resistant α-synuclein is deposited in presynapses in human Lewy body disease and A53T α-synuclein transgenic mice
- (2010) Kunikazu Tanji et al. ACTA NEUROPATHOLOGICA
- When Does Parkinson Disease Start?
- (2010) Rodolfo Savica et al. ARCHIVES OF NEUROLOGY
- Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes
- (2010) Yien-Ming Kuo et al. HUMAN MOLECULAR GENETICS
- Pathogenic Lysosomal Depletion in Parkinson's Disease
- (2010) B. Dehay et al. JOURNAL OF NEUROSCIENCE
- Are synucleinopathies prion-like disorders?
- (2010) Elodie Angot et al. LANCET NEUROLOGY
- When does Parkinson's disease begin?
- (2010) Carles Gaig et al. MOVEMENT DISORDERS
- Alpha-synuclein immunoreactivity in minor salivary gland biopsies of Parkinson's disease patients
- (2010) Maria Graciela Cersósimo et al. MOVEMENT DISORDERS
- What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?
- (2010) David A. Gallagher et al. MOVEMENT DISORDERS
- Evidence in favor of Braak staging of Parkinson's disease
- (2010) Dennis W. Dickson et al. MOVEMENT DISORDERS
- Molecular and clinical prodrome of Parkinson disease: implications for treatment
- (2010) Anthony H. V. Schapira et al. Nature Reviews Neurology
- Gastrointestinal dysfunction in Parkinson’s disease
- (2010) Ronald F. Pfeiffer PARKINSONISM & RELATED DISORDERS
- Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice
- (2010) Francisco Pan-Montojo et al. PLoS One
- The propagation of prion-like protein inclusions in neurodegenerative diseases
- (2010) Michel Goedert et al. TRENDS IN NEUROSCIENCES
- Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction
- (2009) Thomas G. Beach et al. ACTA NEUROPATHOLOGICA
- Parkinson Disease With Dementia
- (2009) Marwan N. Sabbagh et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Parkinson's Disease
- (2009) Christopher H. Hawkes et al. Annals of the New York Academy of Sciences
- Hyposialorrhea as an early manifestation of Parkinson disease
- (2009) M.G. Cersósimo et al. AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
- Lewy Body Pathology in Normal Elderly Subjects
- (2009) William R. Markesbery et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Parkinson's disease: Before the motor symptoms and beyond
- (2009) Amos D. Korczyn et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- Incidental Lewy body disease restricted to the heart and stellate ganglia
- (2009) Yasuo Miki et al. MOVEMENT DISORDERS
- Lesions outside the CNS in Parkinson's disease
- (2009) Ruth Djaldetti et al. MOVEMENT DISORDERS
- Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
- (2009) Yaping Chu et al. NEUROBIOLOGY OF DISEASE
- The locus ceruleus norepinephrine system: Functional organization and potential clinical significance
- (2009) E. E. Benarroch NEUROLOGY
- Diagnosis and the premotor phase of Parkinson disease
- (2009) E. Tolosa et al. NEUROLOGY
- Neuropathology of non-motor features of Parkinson disease
- (2009) Dennis W. Dickson et al. PARKINSONISM & RELATED DISORDERS
- A timeline for Parkinson's disease
- (2009) Christopher H. Hawkes et al. PARKINSONISM & RELATED DISORDERS
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration
- (2009) H. Jang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogenesis of Parkinson's disease: emerging role of molecular chaperones
- (2009) Rina Bandopadhyay et al. TRENDS IN MOLECULAR MEDICINE
- Evidence that incidental Lewy body disease is pre-symptomatic Parkinson’s disease
- (2008) Dennis W. Dickson et al. ACTA NEUROPATHOLOGICA
- The olfactory vector hypothesis of neurodegenerative disease: Is it viable?
- (2008) Richard L. Doty ANNALS OF NEUROLOGY
- Incidental Lewy Body Disease and Preclinical Parkinson Disease
- (2008) Anthony DelleDonne et al. ARCHIVES OF NEUROLOGY
- Sensory deficit in Parkinson's disease: evidence of a cutaneous denervation
- (2008) M. Nolano et al. BRAIN
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Non-motor symptoms in Parkinson’s disease
- (2008) W. Poewe EUROPEAN JOURNAL OF NEUROLOGY
- Lewy Body Pathology Involves Cutaneous Nerves
- (2008) Masako Ikemura et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Incidence and Extent of Lewy Body-Related α-Synucleinopathy in Aging Human Olfactory Bulb
- (2008) Renpei Sengoku et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Olfactory pathogenesis of idiopathic Parkinson disease revisited
- (2008) Alicja Lerner et al. MOVEMENT DISORDERS
- The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years
- (2008) Mariese A. Hely et al. MOVEMENT DISORDERS
- Neural control of the gastrointestinal tract: Implications for Parkinson disease
- (2008) Maria G. Cersosimo et al. MOVEMENT DISORDERS
- Research in motion: the enigma of Parkinson's disease pathology spread
- (2008) Patrik Brundin et al. NATURE REVIEWS NEUROSCIENCE
- Red Blood Cells Are the Major Source of Alpha-Synuclein in Blood
- (2008) Robin Barbour et al. Neurodegenerative Diseases
- Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease?
- (2008) R.J. Phillips et al. NEUROSCIENCE
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