标题
Alpha-synuclein biology in Lewy body diseases
作者
关键词
Multiple System Atrophy, Lewy Body, Dementia With Lewy Body, Lewy Body Disease, Dementia With Lewy Body Patient
出版物
Alzheimers Research & Therapy
Volume 6, Issue 5-8, Pages -
出版商
Springer Nature
发表日期
2014-10-15
DOI
10.1186/s13195-014-0073-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neuropathologic Findings of Dementia with Lewy Bodies (DLB) in a Population-based Vantaa 85+ Study
- (2017) Minna Oinas et al. JOURNAL OF ALZHEIMERS DISEASE
- Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials
- (2014) Markus Mandler et al. ACTA NEUROPATHOLOGICA
- Immunotherapy targeting α-synuclein, with relevance for future treatment of Parkinson’s disease and other Lewy body disorders
- (2014) Veronica Lindström et al. Immunotherapy
- Efficacy and safety of rifampicin for multiple system atrophy: a randomised, double-blind, placebo-controlled trial
- (2014) Phillip A Low et al. LANCET NEUROLOGY
- Roche bets on alpha-synuclein for Parkinson's
- (2014) Gunjan Sinha NATURE BIOTECHNOLOGY
- Extracellular α-synuclein—a novel and crucial factor in Lewy body diseases
- (2014) He-Jin Lee et al. Nature Reviews Neurology
- Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease
- (2014) Gergely Tóth et al. PLoS One
- In vitro aggregation assays for the characterization of α-synuclein prion-like properties
- (2014) Joanna Narkiewicz et al. Prion
- Ceftriaxone Blocks the Polymerization of α-Synuclein and Exerts Neuroprotective Effects in Vitro
- (2013) Paolo Ruzza et al. ACS Chemical Neuroscience
- Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice
- (2013) Nolwen L. Rey et al. ACTA NEUROPATHOLOGICA
- Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties
- (2013) Anna Marchiani et al. AMINO ACIDS
- G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome
- (2013) Suzanne Lesage et al. ANNALS OF NEUROLOGY
- Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys
- (2013) Ariadna Recasens et al. ANNALS OF NEUROLOGY
- Prion-like spreading of pathological α-synuclein in brain
- (2013) Masami Masuda-Suzukake et al. BRAIN
- Prion Disease: A Tale of Folds and Strains
- (2013) Hans Kretzschmar et al. BRAIN PATHOLOGY
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Heat Shock Protein 70 Reduces α-Synuclein-Induced Predegenerative Neuronal Dystrophy in the α-Synuclein Viral Gene Transfer Rat Model of Parkinson's Disease
- (2013) Teresa C. Moloney et al. CNS Neuroscience & Therapeutics
- Caudo-rostral brain spreading of α-synuclein through vagal connections
- (2013) Ayse Ulusoy et al. EMBO Molecular Medicine
- Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
- (2013) David J. Irwin et al. NATURE REVIEWS NEUROSCIENCE
- A novel -synuclein missense mutation in Parkinson disease
- (2013) C. Proukakis et al. NEUROLOGY
- Modeling Lewy pathology propagation in Parkinson's disease
- (2013) Kelvin C. Luk et al. PARKINSONISM & RELATED DISORDERS
- Immunotherapy for neurodegenerative diseases: Focus on α-synucleinopathies
- (2013) Elvira Valera et al. PHARMACOLOGY & THERAPEUTICS
- Structural and functional characterization of two alpha-synuclein strains
- (2013) Luc Bousset et al. Nature Communications
- Targeting heat shock proteins to modulate α-synuclein toxicity
- (2013) Daryl Rhys Jones et al. Therapeutic Advances in Neurological Disorders
- Clinical and multimodal biomarker correlates of ADNI neuropathological findings
- (2013) Jon B Toledo et al. Acta Neuropathologica Communications
- Neuropathologic substrates of Parkinson disease dementia
- (2012) David J. Irwin et al. ANNALS OF NEUROLOGY
- α-Synuclein knockout mice have cognitive impairments
- (2012) V.S. Kokhan et al. BEHAVIOURAL BRAIN RESEARCH
- Biochemical Increase in Phosphorylated Alpha-Synuclein Precedes Histopathology of Lewy-Type Synucleinopathies
- (2012) Lih-Fen Lue et al. BRAIN PATHOLOGY
- Changes in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains
- (2012) Douglas G. Walker et al. EXPERIMENTAL NEUROLOGY
- Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies
- (2012) Kostas Vekrellis et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Reduced parietal connectivity with a premotor writing area in writer's cramp
- (2012) Cathérine C.S. Delnooz et al. MOVEMENT DISORDERS
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Changes in the solubility and phosphorylation of α-synuclein over the course of Parkinson’s disease
- (2011) Jinxia Zhou et al. ACTA NEUROPATHOLOGICA
- Neuropathology underlying clinical variability in patients with synucleinopathies
- (2011) Glenda M. Halliday et al. ACTA NEUROPATHOLOGICA
- Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?
- (2011) Y. Compta et al. BRAIN
- Decreased α-Synuclein Serum Levels in Patients with Lewy Body Dementia Compared to Alzheimer’s Disease Patients and Control Subjects
- (2011) Christoph Laske et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies
- (2011) T. J. Ferman et al. NEUROLOGY
- A novel molecular mechanism for nitrated α-synuclein-induced cell death
- (2011) Yanying Liu et al. Journal of Molecular Cell Biology
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synergistic Interactions between A , Tau, and -Synuclein: Acceleration of Neuropathology and Cognitive Decline
- (2010) L. K. Clinton et al. JOURNAL OF NEUROSCIENCE
- Prion-like transmission of protein aggregates in neurodegenerative diseases
- (2010) Patrik Brundin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Preferentially Increased Nitration of α-Synuclein at Tyrosine-39 in a Cellular Oxidative Model of Parkinson’s Disease
- (2009) Steven R. Danielson et al. ANALYTICAL CHEMISTRY
- SNCAvariants are associated with increased risk for multiple system atrophy
- (2009) Sonja W. Scholz et al. ANNALS OF NEUROLOGY
- Brain α-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation
- (2009) Junchao Tong et al. BRAIN
- Low sensitivity in clinical diagnoses of dementia with Lewy bodies
- (2009) Peter T. Nelson et al. JOURNAL OF NEUROLOGY
- Validation of the Neuropathologic Criteria of the Third Consortium for Dementia With Lewy Bodies for Prospectively Diagnosed Cases
- (2009) Hiroshige Fujishiro et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent -Synuclein Oligomer Formation and Rescue -Synuclein-Induced Toxicity
- (2009) P. Putcha et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
- (2009) Dennis W Dickson et al. LANCET NEUROLOGY
- Alpha-synuclein polymorphisms are associated with Parkinson's disease in a Saskatchewan population
- (2009) Alex Rajput et al. MOVEMENT DISORDERS
- Expanding the clinical phenotype of SNCA duplication carriers
- (2009) Kenya Nishioka et al. MOVEMENT DISORDERS
- Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET
- (2009) H. Shimada et al. NEUROLOGY
- Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy
- (2009) Ammar Al-Chalabi et al. PLoS One
- LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions
- (2008) Yue Huang et al. ACTA NEUROPATHOLOGICA
- The progression of pathology in longitudinally followed patients with Parkinson’s disease
- (2008) Glenda Halliday et al. ACTA NEUROPATHOLOGICA
- Clearance and deposition of extracellular α-synuclein aggregates in microglia
- (2008) He-Jin Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience
- (2008) Gabor G. Kovacs et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Genomewide association study for susceptibility genes contributing to familial Parkinson disease
- (2008) Nathan Pankratz et al. HUMAN GENETICS
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
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