Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease
出版年份 2016 全文链接
标题
Peloruside A: a lead non-taxoid-site microtubule-stabilizing agent with potential activity against cancer, neurodegeneration, and autoimmune disease
作者
关键词
-
出版物
NATURAL PRODUCT REPORTS
Volume 33, Issue 4, Pages 549-561
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-02-12
DOI
10.1039/c5np00146c
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- New marine natural products from sponges (Porifera) of the order Dictyoceratida (2001 to 2012); a promising source for drug discovery, exploration and future prospects
- (2016) Mohammad F. Mehbub et al. BIOTECHNOLOGY ADVANCES
- Microtubule-stabilizing agents: New drug discovery and cancer therapy
- (2016) Ying Zhao et al. PHARMACOLOGY & THERAPEUTICS
- Extreme chromosomal instability forecasts improved outcome in ER-negative breast cancer: a prospective validation cohort study from the TACT trial
- (2015) M. Jamal-Hanjani et al. ANNALS OF ONCOLOGY
- Bioactive natural products from novel microbial sources
- (2015) Victoria L. Challinor et al. Annals of the New York Academy of Sciences
- βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug–tubulin interactions and microtubule stability
- (2015) Arun Kanakkanthara et al. CANCER LETTERS
- Synthetic, semisynthetic and natural analogues of peloruside A
- (2015) Amira Brackovic et al. CHEMICAL COMMUNICATIONS
- Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products
- (2015) Matthew Trendowski DRUGS
- Plants as Factories for Human Pharmaceuticals: Applications and Challenges
- (2015) Jian Yao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of human vascular endothelial cell migration and capillary-like tube formation by the microtubule-stabilizing agent peloruside A
- (2015) Ariane Chan et al. INVESTIGATIONAL NEW DRUGS
- Immunity, inflammation, and cancer: an eternal fight between good and evil
- (2015) Shabnam Shalapour et al. JOURNAL OF CLINICAL INVESTIGATION
- Peloruside A Inhibits Growth of Human Lung and Breast Tumor Xenografts in an Athymic nu/nu Mouse Model
- (2015) C. J. Meyer et al. MOLECULAR CANCER THERAPEUTICS
- Recent Advances in Anti-Angiogenic Therapy of Cancer
- (2015) Rajeev S. Samant et al. Oncotarget
- Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A
- (2014) Andrea E. Prota et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Microtubule-targeting agents are clinically successful due to both mitotic and interphase impairment of microtubule function
- (2014) Jessica J. Field et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease
- (2014) Kurt R. Brunden et al. BIOORGANIC & MEDICINAL CHEMISTRY
- A coupled model of fast axonal transport of organelles and slow axonal transport of tau protein
- (2014) I.A. Kuznetsov et al. COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
- Resistance to Peloruside A and Laulimalide: Functional Significance of Acquired βI-tubulin Mutations at Sites Important for Drug-Tubulin Binding
- (2014) Arun Kanakkanthara et al. CURRENT CANCER DRUG TARGETS
- Recent advances in vascular disrupting agents in cancer therapy
- (2014) Elena Porcù et al. Future Medicinal Chemistry
- Effect of taxoid and nontaxoid site microtubule-stabilizing agents on axonal transport of mitochondria in untransfected and ECFP-htau40-transfected rat cortical neurons in culture
- (2014) Viswanath Das et al. JOURNAL OF NEUROSCIENCE RESEARCH
- An environmental bacterial taxon with a large and distinct metabolic repertoire
- (2014) Micheal C. Wilson et al. NATURE
- The pharmacological bases of the antiangiogenic activity of paclitaxel
- (2013) Guido Bocci et al. ANGIOGENESIS
- A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells
- (2013) Hee-Sheung Lee et al. BMC CANCER
- Biologic therapy for autoimmune diseases: an update
- (2013) Ziv Rosman et al. BMC Medicine
- Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales
- (2013) Asmaa E El-Kenawi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Chromosomal instability (CIN): what it is and why it is crucial to cancer evolution
- (2013) Henry H. Heng et al. CANCER AND METASTASIS REVIEWS
- Synthesis and Biological Activity of 7,8,9-Trideoxy- and 7RDesTHP-Peloruside A
- (2013) Christoph W. Wullschleger et al. CHEMISTRY-A EUROPEAN JOURNAL
- Microtubule-stabilizing agents delay the onset of EAE through inhibition of migration
- (2013) David O'Sullivan et al. IMMUNOLOGY AND CELL BIOLOGY
- Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer
- (2013) Jonathan Welti et al. JOURNAL OF CLINICAL INVESTIGATION
- The causes and consequences of genetic heterogeneity in cancer evolution
- (2013) Rebecca A. Burrell et al. NATURE
- Okadaic acid induced neurotoxicity: An emerging tool to study Alzheimer's disease pathology
- (2013) Pradip K. Kamat et al. NEUROTOXICOLOGY
- Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
- (2013) A. E. Prota et al. SCIENCE
- Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
- (2013) E.-M. Mandelkow et al. Cold Spring Harbor Perspectives in Medicine
- Cytoskeletal Alterations that Confer Resistance to Anti-tubulin Chemotherapeutics
- (2012) Arun Kanakkanthara et al. Anti-Cancer Agents in Medicinal Chemistry
- Non-taxoid site microtubule-stabilizing drugs work independently of tau overexpression in mouse N2a neuroblastoma cells
- (2012) Viswanath Das et al. BRAIN RESEARCH
- MicroRNAs: Novel mediators of resistance to microtubule-targeting agents
- (2012) Arun Kanakkanthara et al. CANCER TREATMENT REVIEWS
- Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid-induced tau phosphorylation
- (2012) Viswanath Das et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Microtubule Stabilizing Agents as Potential Treatment for Alzheimer’s Disease and Related Neurodegenerative Tauopathies
- (2012) Carlo Ballatore et al. JOURNAL OF MEDICINAL CHEMISTRY
- Hyperdynamic Microtubules, Cognitive Deficits, and Pathology Are Improved in Tau Transgenic Mice with Low Doses of the Microtubule-Stabilizing Agent BMS-241027
- (2012) D. M. Barten et al. JOURNAL OF NEUROSCIENCE
- The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice
- (2012) B. Zhang et al. JOURNAL OF NEUROSCIENCE
- Protein–RNA interactions: new genomic technologies and perspectives
- (2012) Julian König et al. NATURE REVIEWS GENETICS
- Random Mutagenesis of β-Tubulin Defines a Set of Dispersed Mutations That Confer Paclitaxel Resistance
- (2012) Shanghua Yin et al. PHARMACEUTICAL RESEARCH
- Acquired Resistance to Peloruside A and Laulimalide is Associated with Downregulation of Vimentin in Human Ovarian Carcinoma Cells
- (2012) Arun Kanakkanthara et al. PHARMACEUTICAL RESEARCH
- Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain
- (2011) Katherine J. Kopeikina et al. AMERICAN JOURNAL OF PATHOLOGY
- Mutations in the β-tubulin binding site for peloruside A confer resistance by targeting a cleft significant in side chain binding
- (2011) Adrian Begaye et al. CELL CYCLE
- Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
- (2011) M. J. Calkins et al. HUMAN MOLECULAR GENETICS
- Hallmarks of Molecular Action of Microtubule Stabilizing Agents
- (2011) Marina Khrapunovich-Baine et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have I-Tubulin Mutations and Altered Expression of II- and III-Tubulin Isotypes
- (2011) A. Kanakkanthara et al. MOLECULAR CANCER THERAPEUTICS
- II-Tubulin and III-Tubulin Mediate Sensitivity to Peloruside A and Laulimalide, but not Paclitaxel or Vinblastine, in Human Ovarian Carcinoma Cells
- (2011) A. Kanakkanthara et al. MOLECULAR CANCER THERAPEUTICS
- Structure–activity studies of the pelorusides: new congeners and semi-synthetic analogues
- (2011) A. Jonathan Singh et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Successes and pitfalls of the aquaculture of the sponge Mycale hentscheli
- (2010) Michael J. Page et al. AQUACULTURE
- An okadaic acid-induced model of tauopathy and cognitive deficiency
- (2010) Zhang Zhang et al. BRAIN RESEARCH
- Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells
- (2010) Anja Wilmes et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Molecular Recognition of Peloruside A by Microtubules. The C24 Primary Alcohol is Essential for Biological Activity
- (2010) Benet Pera et al. CHEMBIOCHEM
- Tau in Alzheimer Disease and Related Tauopathies
- (2010) K. Iqbal et al. Current Alzheimer Research
- Peloruside A inhibits microtubule dynamics in a breast cancer cell line MCF7
- (2010) Ariane Chan et al. INVESTIGATIONAL NEW DRUGS
- The Assembly-Inducing Laulimalide/Peloruside A Binding Site on Tubulin: Molecular Modeling and Biochemical Studies with [3H]Peloruside A
- (2010) Tam Luong Nguyen et al. Journal of Chemical Information and Modeling
- Epothilone D Improves Microtubule Density, Axonal Integrity, and Cognition in a Transgenic Mouse Model of Tauopathy
- (2010) K. R. Brunden et al. JOURNAL OF NEUROSCIENCE
- Microtubule-Stabilizing Drugs from Marine Sponges: Focus on Peloruside A and Zampanolide
- (2010) John H. Miller et al. Marine Drugs
- Human Mutations That Confer Paclitaxel Resistance
- (2010) S. Yin et al. MOLECULAR CANCER THERAPEUTICS
- Microtubule-binding agents: a dynamic field of cancer therapeutics
- (2010) Charles Dumontet et al. NATURE REVIEWS DRUG DISCOVERY
- Stereoselective Synthesis of a Monocyclic Peloruside A Analogue
- (2010) Christoph W. Wullschleger et al. ORGANIC LETTERS
- Delaying the onset of experimental autoimmune encephalomyelitis with the microtubule-stabilizing compounds, paclitaxel and Peloruside A
- (2009) Kevin P. Crume et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Peloruside B, A Potent Antitumor Macrolide from the New Zealand Marine Sponge Mycale hentscheli: Isolation, Structure, Total Synthesis, and Bioactivity
- (2009) A. Jonathan Singh et al. JOURNAL OF ORGANIC CHEMISTRY
- Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis
- (2009) Andrew J. Holland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
- (2009) Aniek Janssen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of Axonal Transport in Neurodegenerative Diseases
- (2008) Kurt J. De Vos et al. Annual Review of Neuroscience
- Association between chromosomal instability and prognosis in colorectal cancer: a meta-analysis
- (2008) A Walther et al. GUT
- A Unique Mode of Microtubule Stabilization Induced by Peloruside A
- (2008) J. Torin Huzil et al. JOURNAL OF MOLECULAR BIOLOGY
- Chromosomal instability is a risk factor for poor prognosis of adenocarcinoma of the lung: Fluorescence in situ hybridization analysis of paraffin-embedded tissue from Korean patients
- (2008) Chang-Min Choi et al. LUNG CANCER
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
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