Microtubule-Stabilizing Drugs from Marine Sponges: Focus on Peloruside A and Zampanolide

Clinical Status of Anti-Cancer Agents Derived from Marine Sources

(2013) Ram Singh et al.   Anti-Cancer Agents in Medicinal Chemistry

Marine Macrolides, a Promising Source of Antitumor Compounds

(2012) Jose Napolitano et al.   Anti-Cancer Agents in Medicinal Chemistry

Peloruside A inhibits microtubule dynamics in a breast cancer cell line MCF7

(2010) Ariane Chan et al.   INVESTIGATIONAL NEW DRUGS

Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells

(2010) Anja Wilmes et al.   INVESTIGATIONAL NEW DRUGS

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui

(2009) G. Gurel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Distinct Pose of Discodermolide in Taxol Binding Pocket Drives a Complementary Mode of Microtubule Stabilization

(2009) Marina Khrapunovich-Baine et al.   BIOCHEMISTRY

Impact of Natural Products on Developing New Anti-Cancer Agents†

(2009) Gordon M. Cragg et al.   CHEMICAL REVIEWS

Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIII

(2009) Yongjun Dang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delaying the onset of experimental autoimmune encephalomyelitis with the microtubule-stabilizing compounds, paclitaxel and Peloruside A

(2009) Kevin P. Crume et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microtubule-Stabilizing Activity of Zampanolide, a Potent Macrolide Isolated from the Tongan Marine SpongeCacospongia mycofijiensis

(2009) Jessica J. Field et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Selective Account of Effective Paradigms and Significant Outcomes in the Discovery of Inspirational Marine Natural Products⊥†

(2009) Koneni V. Sashidhara et al.   JOURNAL OF NATURAL PRODUCTS

Tubulin-Interactive Natural Products as Anticancer Agents(1)

(2009) David G. I. Kingston   JOURNAL OF NATURAL PRODUCTS

Peloruside B, A Potent Antitumor Macrolide from the New Zealand Marine Sponge Mycale hentscheli: Isolation, Structure, Total Synthesis, and Bioactivity

(2009) A. Jonathan Singh et al.   JOURNAL OF ORGANIC CHEMISTRY

An Aldol-Based Synthesis of (+)-Peloruside A, A Potent Microtubule Stabilizing Agent

(2009) David A. Evans et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Marine natural products

(2009) John W. Blunt et al.   NATURAL PRODUCT REPORTS

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies

(2009) Kurt R. Brunden et al.   NATURE REVIEWS DRUG DISCOVERY

Total Synthesis of (−)-Zampanolide and Questionable Existence of (−)-Dactylolide as the Elusive Biosynthetic Precursor of (−)-Zampanolide in an Okinawan Sponge

(2009) Jun’ichi Uenishi et al.   ORGANIC LETTERS

Microtubule Active Agents: Beyond the Taxane Frontier

(2008) P. G. Morris et al.   CLINICAL CANCER RESEARCH

A Unique Mode of Microtubule Stabilization Induced by Peloruside A

(2008) J. Torin Huzil et al.   JOURNAL OF MOLECULAR BIOLOGY

Total Synthesis of (−)-Dactylolide and Formal Synthesis of (−)-Zampanolide via Target Oriented β-C-Glycoside Formation

(2008) Fei Ding et al.   JOURNAL OF ORGANIC CHEMISTRY

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY

Enantioselective Total Synthesis of Peloruside A:  A Potent Microtubule Stabilizer

(2008) Arun K. Ghosh et al.   ORGANIC LETTERS