Blocking salt‐inducible kinases with YKL‐06‐061 prevents PTZ‐induced seizures in mice

SIK3 and Wnk converge on Fray to regulate glial K+ buffering and seizure susceptibility

(2023) Lorenzo Lones et al.   PLoS Genetics

Selective Neuronal Knockout of STAT3 Function Inhibits Epilepsy Progression, Improves Cognition, and Restores Dysregulated Gene Networks in a Temporal Lobe Epilepsy Model

(2023) Allison E. Tipton et al.   ANNALS OF NEUROLOGY

Effect of repeated seizures on spatial exploration and immediate early gene expression in the hippocampus and dentate gyrus

(2022) Alena Kalinina et al.   IBRO Neuroscience Reports

An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice

(2022) Bo Pang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy

(2022) Lukas Henning et al.   GLIA

The Selective SIK2 Inhibitor ARN-3236 Produces Strong Antidepressant-Like Efficacy in Mice via the Hippocampal CRTC1-CREB-BDNF Pathway

(2021) Yue Liu et al.   Frontiers in Pharmacology

Cholinergic transmission from the basal forebrain modulates social memory in male mice

(2021) Ornela Kljakic et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1

(2021) Moataz Badawi et al.   Frontiers in Molecular Neuroscience

Adult food choices depend on sex and exposure to early-life stress: Underlying brain circuitry, adipose tissue adaptations and metabolic responses

(2021) S.R. Ruigrok et al.   Neurobiology of Stress

Irradiation increases brain-derived neurotrophic factor precursor signaling in the mouse hippocampus

(2020) Zhen Wang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

PTZ-induced seizures in mice require a revised Racine scale

(2019) Jan Van Erum et al.   EPILEPSY & BEHAVIOR

Valproic acid and epilepsy: from molecular mechanisms to clinical evidences

(2018) Michele Romoli et al.   Current Neuropharmacology

Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a

(2017) Wei Shan et al.   JOURNAL OF NEUROCHEMISTRY

Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits

(2017) Jason C You et al.   NATURE MEDICINE

Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice

(2017) Mandeep Kumar et al.   NEUROSCIENCE RESEARCH

A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin

(2017) Nisma Mujahid et al.   Cell Reports

Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology

(2016) Christoph Pröschel et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Microglia-Neuron Communication in Epilepsy

(2016) Ukpong B. Eyo et al.   GLIA

Prevalence and incidence of epilepsy

(2016) Kirsten M. Fiest et al.   NEUROLOGY

De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies

(2015) Jeanne Hansen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice

(2015) Erica Korb et al.   NATURE NEUROSCIENCE

The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock

(2013) Aarti Jagannath et al.   CELL

Sudden unexpected death in a mouse model of Dravet syndrome

(2013) Franck Kalume et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of pentoxifylline and H-89 on epileptogenic activity of bucladesine in pentylenetetrazol-treated mice

(2011) Mahshid Sadat Hosseini-Zare et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Deletion of the potassium channel Kv12.2 causes hippocampal hyperexcitability and epilepsy

(2010) Xiaofei Zhang et al.   NATURE NEUROSCIENCE