An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice

Hormonal Therapy for Infantile Spasms: A Systematic Review and Meta-Analysis

(2022) Shiqi Guang et al.   Frontiers in Neurology

Novel mutation of SIK1 gene causing a mild form of pediatric epilepsy in a Chinese patient

(2022) Wangshu Xu et al.   METABOLIC BRAIN DISEASE

Combined melatonin and adrenocorticotropic hormone treatment attenuates N-methyl-d-aspartate-induced infantile spasms in a rat model by regulating activation of the HPA axis

(2021) Lin Wan et al.   NEUROSCIENCE LETTERS

Nuts and bolts of the salt-inducible kinases (SIKs)

(2021) Nicola J. Darling et al.   BIOCHEMICAL JOURNAL

Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1

(2021) Moataz Badawi et al.   Frontiers in Molecular Neuroscience

Stress and central autonomic network

(2021) Guillaume Lamotte et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

IQSEC3 deletion impairs fear memory through upregulation of ribosomal S6 kinase 1 signaling in the hippocampus

(2021) Dongwook Kim et al.   BIOLOGICAL PSYCHIATRY

IQSEC2 Deficiency Results in Abnormal Social Behaviors Relevant to Autism by Affecting Functions of Neural Circuits in the Medial Prefrontal Cortex

(2021) Anuradha Mehta et al.   Cells

DNA repair protein RAD51 enhances the CRISPR/Cas9-mediated knock-in efficiency in brain neurons

(2020) Taiga Kurihara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Early developmental electroencephalography abnormalities, neonatal seizures, and induced spasms in a mouse model of tuberous sclerosis complex

(2020) Nicholas Rensing et al.   EPILEPSIA

Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need

(2020) Minjeong Park et al.   Scientific Reports

Modeling epileptic spasms during infancy: Are we heading for the treatment yet?

(2020) Libor Velíšek et al.   PHARMACOLOGY & THERAPEUTICS

Inhibition of DNA ligase IV enhances the CRISPR/Cas9-mediated knock-in efficiency in mouse brain neurons

(2020) Xueshan Cao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deficiency of calcium/calmodulin-dependent serine protein kinase disrupts the excitatory-inhibitory balance of synapses by down-regulating GluN2B

(2019) Takuma Mori et al.   MOLECULAR PSYCHIATRY

Anabolic and Pro-metabolic Functions of CREB-CRTC in Skeletal Muscle: Advantages and Obstacles for Type 2 Diabetes and Cancer Cachexia

(2019) Rebecca Berdeaux et al.   Frontiers in Endocrinology

Salt-Inducible Kinases: Physiology, Regulation by cAMP, and Therapeutic Potential

(2018) Marc N. Wein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells

(2018) Ken-ichiro Kuwako et al.   Cell Reports

The Salt-Inducible Kinases: Emerging Metabolic Regulators

(2018) Kei Sakamoto et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects

(2017) Konrad Platzer et al.   JOURNAL OF MEDICAL GENETICS

A Quantitative Analysis of the Distribution of CRH Neurons in Whole Mouse Brain

(2017) Jie Peng et al.   Frontiers in Neuroanatomy

Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse

(2016) Junko Kono et al.   Brain Structure & Function

Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology

(2016) Christoph Pröschel et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Fluorescent protein tagging of endogenous protein in brain neurons using CRISPR/Cas9-mediated knock-in and in utero electroporation techniques

(2016) Takeshi Uemura et al.   Scientific Reports

De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies

(2015) Jeanne Hansen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Development of a mouse model of infantile spasms induced by N -methyl- d -aspartate

(2015) Xiu-Yu Shi et al.   EPILEPSY RESEARCH

Simple Genome Editing of Rodent Intact Embryos by Electroporation

(2015) Takehito Kaneko et al.   PLoS One

Rabies virus glycoprotein variants display different patterns in rabies monosynaptic tracing

(2014) Takuma Mori et al.   Frontiers in Neuroanatomy

GRIN2Bmutations in west syndrome and intellectual disability with focal epilepsy

(2013) Johannes R. Lemke et al.   ANNALS OF NEUROLOGY

The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock

(2013) Aarti Jagannath et al.   CELL

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Transgenic Mice Expressing Green Fluorescent Protein under the Control of the Corticotropin-Releasing Hormone Promoter

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Regulation of CREB-mediated gene expression by salt inducible kinase

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