An integrated strategy combining UPLC-MS/MS, chemometrics, molecular docking, and molecular dynamics simulation for metabolic profiling of onion (Allium cepa L.) cultivars and unravelling potential anti-COVID-19 metabolites

SARS-CoV-2 Envelope (E) Protein Binds and Activates TLR2 Pathway: A Novel Molecular Target for COVID-19 Interventions

(2022) Rémi Planès et al.   Viruses-Basel

Anthocyanins in Red Jasmine Rice (Oryza sativa L.) Extracts and Efficacy on Inhibition of Herpes Simplex Virus, Free Radicals and Cancer Cell

(2022) Boonpa Suantai et al.   Nutrients

Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies

(2022) Mithun Rudrapal et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Inhibition of Human Respiratory Influenza A Virus and Human Betacoronavirus-1 by the Blend of Double-Standardized Extracts of Aronia melanocarpa (Michx.) Elliot and Sambucus nigra L.

(2022) Michał Ochnik et al.   Pharmaceuticals

Emergence of SARS‐CoV‐2 Omicron BA.5 variant of concern in Western Pennsylvania, United States

(2022) Tung Phan et al.   JOURNAL OF MEDICAL VIROLOGY

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

(2022) Yunlong Cao et al.   NATURE

Equilibrium of Tiered Healthcare Resources during the COVID-19 Pandemic in China: A Case Study of Taiyuan, Shanxi Province

(2022) Xueling Wu et al.   International Journal of Environmental Research and Public Health

In Vitro Bioaccessibility and Anti-Inflammatory Activity of a Chemically Characterized Allium cepa L. Extract Rich in Quercetin Derivatives Optimized by the Design of Experiments

(2022) Hammad Ullah et al.   MOLECULES

Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP

(2021) Katerina Naydenova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Onion Peel: Turning a Food Waste into a Resource

(2021) Rita Celano et al.   Antioxidants

Pharmacoinformatics and molecular dynamics simulation-based phytochemical screening of neem plant (Azadiractha indica) against human cancer by targeting MCM7 protein

(2021) Foysal Ahammad et al.   BRIEFINGS IN BIOINFORMATICS

In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase

(2021) Ismail Celik et al.   MOLECULAR DIVERSITY

Chlorogenic acid, a natural product as potential inhibitor of COVID-19: virtual screening experiment based on network pharmacology and molecular docking

(2021) Wen-Xiang Wang et al.   NATURAL PRODUCT RESEARCH

Combined molecular docking and dynamics simulations studies of natural compounds as potent inhibitors against SARS-CoV-2 main protease

(2021) Mebarka Ouassaf et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

In Silico Evaluation of Iranian Medicinal Plant Phytoconstituents as Inhibitors against Main Protease and the Receptor-Binding Domain of SARS-CoV-2

(2021) Seyyed Sasan Mousavi et al.   MOLECULES

Kaempferol inhibits Pseudorabies virus replication in vitro through regulation of MAPKs and NF-κB signaling pathways

(2021) Xu CHEN et al.   Journal of Integrative Agriculture

Micronutrients for potential therapeutic use against COVID-19; a review

(2021) Richard A. Giovane et al.   Clinical Nutrition ESPEN

Integrative Analyses of Widely Targeted Metabolic Profiling and Transcriptome Data Reveals Molecular Insight into Metabolomic Variations during Apple (Malus domestica) Fruit Development and Ripening

(2020) Jidi Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA‐dependent RNA polymerase of SARS‐CoV‐2 as a therapeutic target

(2020) Yanyan Wang et al.   JOURNAL OF MEDICAL VIROLOGY

RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19

(2020) Yi Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural basis for the inhibition of SARS-CoV2 main protease by Indian medicinal plant-derived antiviral compounds

(2020) Konda Mani Saravanan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Efficacy-directed discrimination of the essential oils of three Juniperus species based on their in-vitro antimicrobial and anti-inflammatory activities

(2020) Reham S. Darwish et al.   JOURNAL OF ETHNOPHARMACOLOGY

Structural basis of antiviral activity of caffeic acid against severe fever with thrombocytopenia syndrome virus

(2020) Motohiko Ogawa et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Antiviral potential of garlic (Allium sativum) and its organosulfur compounds: A systematic update of pre-clinical and clinical data

(2020) Razina Rouf et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Antiviral activity of a novel mixture of natural antimicrobials, in vitro, and in a chicken infection model in vivo

(2020) Igori Balta et al.   Scientific Reports

In silico identification of Tretinoin as a SARS-CoV-2 envelope (E) protein ion channel inhibitor

(2020) Debajit Dey et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Remdesivir Is Effective in Combating COVID-19 because It Is a Better Substrate than ATP for the Viral RNA-Dependent RNA Polymerase

(2020) Tyler L. Dangerfield et al.   iScience

Response surface methodology to optimize supercritical carbon dioxide/co-solvent extraction of brown onion skin by-product as source of nutraceutical compounds

(2018) Luca Campone et al.   FOOD CHEMISTRY

Traditional and modern uses of onion bulb (Allium cepa L.): A systematic review

(2018) Joaheer D. Teshika et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Deep Annotation of Hydroxycinnamic Acid Amides in Plants Based on Ultra-High-Performance Liquid Chromatography–High-Resolution Mass Spectrometry and Its In Silico Database

(2018) Zaifang Li et al.   ANALYTICAL CHEMISTRY

Genetics of bulb colour variation and flavonoids in onion

(2018) Kiran Khandagale et al.   JOURNAL OF HORTICULTURAL SCIENCE & BIOTECHNOLOGY

Comparison of high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD) and ultra-high performance liquid chromatography with evaporative light scattering (UHPLC-ELSD) for the analyses of fructooligosaccharides in onion ( Allium cepa L.)

(2017) Tobias Pöhnl et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Comprehensive metabolite profiling of onion bulbs (Allium cepa) using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry

(2017) Christoph Böttcher et al.   Metabolomics

Porcine Rotaviruses: Epidemiology, Immune Responses and Control Strategies

(2017) Anastasia Vlasova et al.   Viruses-Basel

Analysis of a series of chlorogenic acid isomers using differential ion mobility and tandem mass spectrometry

(2016) Jamie L. Willems et al.   ANALYTICA CHIMICA ACTA

Development and virucidal activity of a novel alcohol-based hand disinfectant supplemented with urea and citric acid

(2016) Georgios Ionidis et al.   BMC INFECTIOUS DISEASES

Structural Characterization of Flavonoid Glycoconjugates and Their Derivatives with Mass Spectrometric Techniques

(2016) Piotr Kachlicki et al.   MOLECULES

Total phenolics, antioxidant and xanthine oxidase inhibitory activity of three colored onions (Allium cepaL.)

(2014) Shivraj Hariram Nile et al.   Frontiers in Life Science

Onion: Nature Protection Against Physiological Threats

(2013) Hafiz Ansar Rasul Suleria et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Increasing the Added-Value of Onions as a Source of Antioxidant Flavonoids: A Critical Review

(2013) M. R. Pérez-Gregorio et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Docking performance of the glide program as evaluated on the Astex and DUD datasets: a complete set of glide SP results and selected results for a new scoring function integrating WaterMap and glide

(2012) Matthew P. Repasky et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Identification and Quantitation of Unsaturated Fatty Acid Isomers by Electrospray Ionization Tandem Mass Spectrometry: A Shotgun Lipidomics Approach

(2011) Kui Yang et al.   ANALYTICAL CHEMISTRY

Quercetin and Isorhamnetin Glycosides in Onion (Allium cepaL.): Varietal Comparison, Physical Distribution, Coproduct Evaluation, and Long-Term Storage Stability

(2011) Jihyun Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Review on the Dietary Flavonoid Kaempferol

(2011) J. M. Calderon-Montano et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Content of quercetin glycosides and fructooligosaccharides in onion stored in a cold room

(2009) Katarzyna Grzelak et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY