Assessing utility of thyroid in vitro screening assays through comparisons to observed impacts in vivo
出版年份 2023 全文链接
标题
Assessing utility of thyroid in vitro screening assays through comparisons to observed impacts in vivo
作者
关键词
-
出版物
REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 144, Issue -, Pages 105491
出版商
Elsevier BV
发表日期
2023-09-04
DOI
10.1016/j.yrtph.2023.105491
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Mechanisms by Which Inducers of Drug Metabolizing Enzymes Alter Thyroid Hormones in Rats
- (2022) Nichole R Vansell DRUG METABOLISM AND DISPOSITION
- IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making
- (2022) Xiaoqing Chang et al. Toxics
- Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase
- (2022) Jennifer H. Olker et al. AQUATIC TOXICOLOGY
- Histopathological, immunohistochemical, and molecular investigation of atrazine toxic effect on some organs of adult male albino rats with a screening of Acacia nilotica as a protective trial
- (2022) Zainab Sabry Othman Ahmed et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Advances in computational methods along the exposure to toxicological response paradigm
- (2022) Hisham El-Masri et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures
- (2021) Jill A. Franzosa et al. npj Systems Biology and Applications
- Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals
- (2021) Sally A. Mayasich et al. TOXICOLOGY IN VITRO
- Multi Species Analyses Reveal Testicular T3 Metabolism and Signalling as a Target of Environmental Pesticides
- (2021) Valeria Nittoli et al. Cells
- Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay
- (2020) Angela R. Buckalew et al. ARCHIVES OF TOXICOLOGY
- Testing for thyroid hormone disruptors, a review of non-mammalian in vivo models
- (2020) Stephan Couderq et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Induction of immunological, hormonal and histological alterations after sublethal exposure of chlorpyrifos in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795)
- (2020) K.P. Raibeemol et al. FISH & SHELLFISH IMMUNOLOGY
- Peripheral T3 signaling is target of pesticides in zebrafish larvae and adult liver
- (2020) Marco Colella et al. JOURNAL OF ENDOCRINOLOGY
- Anthropogenic stressors impact fish sensory development and survival via thyroid disruption
- (2020) Marc Besson et al. Nature Communications
- Adversity Considerations for Thyroid Follicular Cell Hypertrophy and Hyperplasia in Nonclinical Toxicity Studies: Results From the 6th ESTP International Expert Workshop
- (2020) Maike Huisinga et al. TOXICOLOGIC PATHOLOGY
- Crosstalk of cholinergic pathway on thyroid disrupting effects of the insecticide chlorpyrifos in zebrafish (Danio rerio)
- (2020) Kun Qiao et al. SCIENCE OF THE TOTAL ENVIRONMENT
- PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism
- (2020) Mei Ha et al. SCIENCE OF THE TOTAL ENVIRONMENT
- In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase
- (2020) Jennifer H. Olker et al. TOXICOLOGY IN VITRO
- The next generation blueprint of computational toxicology at the U.S. Environmental Protection Agency
- (2019) Russell S Thomas et al. TOXICOLOGICAL SCIENCES
- Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches
- (2019) Pamela D. Noyes et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library
- (2019) Katie Paul-Friedman et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Nuclear receptors are important targets of environmental disrupting compounds
- (2019) Lucia Toporova et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Thyroid-disrupting effects of chlorpyrifos in female Wistar rats
- (2019) Joice Karina Otênio et al. DRUG AND CHEMICAL TOXICOLOGY
- The effect of chlorpyrifos on salinity acclimation of juvenile rainbow trout ( Oncorhynchus mykiss )
- (2018) Bagher Mojazi Amiri et al. AQUATIC TOXICOLOGY
- High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library
- (2018) Jun Wang et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Differentiating Pathway-Specific From Nonspecific Effects in High-Throughput Toxicity Data: A Foundation for Prioritizing Adverse Outcome Pathway Development
- (2018) Kellie A Fay et al. TOXICOLOGICAL SCIENCES
- The US Federal Tox21 Program: A strategic and operational plan for continued leadership
- (2018) Russell Thomas ALTEX-Alternatives to Animal Experimentation
- Acute exposure of zebrafish embryo (Danio rerio) to flutolanil reveals its developmental mechanism of toxicity via disrupting the thyroid system and metabolism
- (2018) Miaomiao Teng et al. ENVIRONMENTAL POLLUTION
- Endpoint sensitivity in Amphibian Metamorphosis Assay
- (2018) ZhiChao Dang ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results
- (2018) Carlie A. LaLone et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases
- (2018) Jennifer H Olker et al. TOXICOLOGICAL SCIENCES
- Reflections on the progress towards non-animal methods for acute toxicity testing of chemicals
- (2018) Helen Prior et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
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- Species Differences in the Binding of Sodium 4-Phenylbutyrate to Serum Albumin
- (2017) Keishi Yamasaki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Relevance and reliability of experimental data in human health risk assessment of pesticides
- (2017) Johanna Kaltenhäuser et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity
- (2017) Michael W Hornung et al. TOXICOLOGICAL SCIENCES
- Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)
- (2017) Daniel R. Hallinger et al. TOXICOLOGY IN VITRO
- The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
- (2017) Antony J. Williams et al. Journal of Cheminformatics
- Fish larval recruitment to reefs is a thyroid hormone-mediated metamorphosis sensitive to the pesticide chlorpyrifos
- (2017) Guillaume Holzer et al. eLife
- tcpl: the ToxCast pipeline for high-throughput screening data
- (2016) Dayne L. Filer et al. BIOINFORMATICS
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- (2016) Nicole C. Kleinstreuer et al. CHEMICAL RESEARCH IN TOXICOLOGY
- A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study
- (2016) Katie Paul Friedman et al. CRITICAL REVIEWS IN TOXICOLOGY
- A Nonradioactive DEHAL Assay for Testing Substrates, Inhibitors, and Monitoring Endogenous Activity
- (2016) Kostja Renko et al. ENDOCRINOLOGY
- Identifying reference chemicals for thyroid bioactivity screening
- (2016) Susanna Wegner et al. REPRODUCTIVE TOXICOLOGY
- Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space
- (2016) Richard Judson et al. TOXICOLOGICAL SCIENCES
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- (2016) Katie Paul Friedman et al. TOXICOLOGICAL SCIENCES
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- (2015) Patience Browne et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
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- (2015) Frances Xin et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- An Improved Nonradioactive Screening Method Identifies Genistein and Xanthohumol as Potent Inhibitors of Iodothyronine Deiodinases
- (2015) Kostja Renko et al. THYROID
- Integrated Model of Chemical Perturbations of a Biological Pathway Using 18In VitroHigh-Throughput Screening Assays for the Estrogen Receptor
- (2015) Richard S. Judson et al. TOXICOLOGICAL SCIENCES
- Development of a Thyroperoxidase Inhibition Assay for High-Throughput Screening
- (2014) Katie B. Paul et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Should oral gavage be abandoned in toxicity testing of endocrine disruptors?
- (2014) Laura N Vandenberg et al. Environmental Health
- ENDOCRINE DISRUPTION: Developmental Picture Window
- (2014) Julia R. Barrett ENVIRONMENTAL HEALTH PERSPECTIVES
- Protective role of Nigella sativa oil against reproductive toxicity, hormonal alterations, and oxidative damage induced by chlorpyrifos in male rats
- (2014) Rachid Mosbah et al. TOXICOLOGY AND INDUSTRIAL HEALTH
- Lessons learned, challenges, and opportunities: The U.S. Endocrine Disruptor Screening Program
- (2014) ALTEX-Alternatives to Animal Experimentation
- Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat
- (2013) Katie B. Paul et al. TOXICOLOGY
- Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals
- (2013) AlberTinka J. Murk et al. TOXICOLOGY IN VITRO
- Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management
- (2012) Robert Kavlock et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Identification of Iopanoic Acid as Substrate of Type 1 Deiodinase by a Novel Nonradioactive Iodide-Release Assay
- (2012) Kostja Renko et al. ENDOCRINOLOGY
- Thyroid effects of endocrine disrupting chemicals
- (2011) Malene Boas et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Evaluation of EPA’s Tier 1 Endocrine Screening Battery and recommendations for improving the interpretation of screening results
- (2011) Christopher J. Borgert et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Application of an Integrated Testing Strategy to the U.S. EPA Endocrine Disruptor Screening Program
- (2011) Catherine E. Willett et al. TOXICOLOGICAL SCIENCES
- Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets
- (2011) Thomas B. Knudsen et al. TOXICOLOGY
- Impact of Environmental Chemicals on Key Transcription Regulators and Correlation to Toxicity End Points within EPA’s ToxCast Program
- (2010) Matthew T. Martin et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
- (2010) Gerald T. Ankley et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis
- (2010) Kristin A. Connors et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Xenobiotic-Metabolizing Enzyme and Transporter Gene Expression in Primary Cultures of Human Hepatocytes Modulated by Toxcast Chemicals
- (2010) Daniel M. Rotroff et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- Role of UDP-Glucuronosyltransferase (UGT) 2B2 in Metabolism of Triiodothyronine: Effect of Microsomal Enzyme Inducers in Sprague Dawley and UGT2B2-Deficient Fischer 344 Rats
- (2010) Terrilyn A. Richardson et al. TOXICOLOGICAL SCIENCES
- Assessing Hormone Receptor Activities of Pyrethroid Insecticides and Their Metabolites in Reporter Gene Assays
- (2010) Guizhen Du et al. TOXICOLOGICAL SCIENCES
- Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay
- (2010) Jaime Freitas et al. TOXICOLOGY IN VITRO
- “ToxRTool”, a new tool to assess the reliability of toxicological data
- (2009) Klaus Schneider et al. TOXICOLOGY LETTERS
- The Roles of Nuclear Receptors CAR and PXR in Hepatic Energy Metabolism
- (2008) Yoshihiro Konno et al. Drug Metabolism and Pharmacokinetics
- Homogeneous reporter system enables quantitative functional assessment of multiple transcription factors
- (2008) Sergei Romanov et al. NATURE METHODS
- Transforming Environmental Health Protection
- (2008) Francis S. Collins et al. SCIENCE
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