Advances in computational methods along the exposure to toxicological response paradigm
出版年份 2022 全文链接
标题
Advances in computational methods along the exposure to toxicological response paradigm
作者
关键词
-
出版物
TOXICOLOGY AND APPLIED PHARMACOLOGY
Volume 450, Issue -, Pages 116141
出版商
Elsevier BV
发表日期
2022-06-29
DOI
10.1016/j.taap.2022.116141
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Predicting molecular initiating events using chemical target annotations and gene expression
- (2022) Joseph L. Bundy et al. BioData Mining
- In Silico Prediction of Input Parameters for Simplified Physiologically Based Pharmacokinetic Models for Estimating Plasma, Liver, and Kidney Exposures in Rats after Oral Doses of 246 Disparate Chemicals
- (2021) Yusuke Kamiya et al. CHEMICAL RESEARCH IN TOXICOLOGY
- A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium
- (2021) John Rooney et al. CHEMICAL RESEARCH IN TOXICOLOGY
- High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures
- (2021) Jill A. Franzosa et al. npj Systems Biology and Applications
- Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition
- (2021) Jun Wang et al. ARCHIVES OF TOXICOLOGY
- High-Throughput Transcriptomics Platform for Screening Environmental Chemicals
- (2021) Joshua A Harrill et al. TOXICOLOGICAL SCIENCES
- Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models
- (2021) Susana Proença et al. TOXICOLOGY IN VITRO
- Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals
- (2021) Sally A. Mayasich et al. TOXICOLOGY IN VITRO
- Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells
- (2021) Eunnara Cho et al. ARCHIVES OF TOXICOLOGY
- Generalized Read-Across prediction using genra-py
- (2021) Imran Shah et al. BIOINFORMATICS
- Identifying Chemicals and Mixtures of Potential Biological Concern Detected in Passive Samplers from Great Lakes Tributaries Using High‐throughput Data and Biological Pathways
- (2021) David A. Alvarez et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Sourcing data on chemical properties and hazard data from the US-EPA CompTox Chemicals Dashboard: A practical guide for human risk assessment
- (2021) Antony J. Williams et al. ENVIRONMENT INTERNATIONAL
- A Comprehensive Non-targeted Analysis Study of the Prenatal Exposome
- (2021) Dimitri Panagopoulos Abrahamsson et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Chemical Characterization of Recycled Consumer Products Using Suspect Screening Analysis
- (2021) Charles N. Lowe et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- High-throughput PBTK models for in vitro to in vivo extrapolation
- (2021) Miyuki Breen et al. Expert Opinion on Drug Metabolism & Toxicology
- Estimating mouthing exposure to chemicals in children’s products
- (2021) Nicolò Aurisano et al. Journal of Exposure Science and Environmental Epidemiology
- Reconnaissance of cumulative risk of pesticides and pharmaceuticals in Great Smoky Mountains National Park streams
- (2021) Paul M. Bradley et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Potency ranking of per- and polyfluoroalkyl substances using high-throughput transcriptomic analysis of human liver spheroids
- (2021) A J F Reardon et al. TOXICOLOGICAL SCIENCES
- Bioactivity profiling of per- and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure
- (2021) Keith A. Houck et al. TOXICOLOGY
- Quantitative non-targeted analysis: Bridging the gap between contaminant discovery and risk characterization
- (2021) James P. McCord et al. ENVIRONMENT INTERNATIONAL
- Correction to Designing QSARs for Parameters of High Throughput Toxicokinetic Models Using Open-Source Descriptors
- (2021) Daniel E. Dawson et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay
- (2020) Angela R. Buckalew et al. ARCHIVES OF TOXICOLOGY
- Profiling the ToxCast library with a pluripotent human (H9) stem cell line-based biomarker assay for developmental toxicity
- (2020) Todd J Zurlinden et al. TOXICOLOGICAL SCIENCES
- High-throughput screening tools facilitate calculation of a combined exposure-bioactivity index for chemicals with endocrine activity
- (2020) Susanna H. Wegner et al. ENVIRONMENT INTERNATIONAL
- A next generation risk assessment case study for coumarin in cosmetic products
- (2020) M T Baltazar et al. TOXICOLOGICAL SCIENCES
- New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing
- (2020) Jose Zavala et al. International Journal of Environmental Research and Public Health
- Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals
- (2020) Risa R. Sayre et al. Scientific Data
- Suspect and non-targeted screening of chemicals of emerging concern for human biomonitoring, environmental health studies and support to risk assessment: From promises to challenges and harmonisation issues
- (2020) Mariane Pourchet et al. ENVIRONMENT INTERNATIONAL
- Development and evaluation of a high throughput inhalation model for organic chemicals
- (2020) Matthew W. Linakis et al. Journal of Exposure Science and Environmental Epidemiology
- A cross-platform approach to characterize and screen potential neurovascular unit toxicants
- (2020) Todd J. Zurlinden et al. REPRODUCTIVE TOXICOLOGY
- Evaluation of a multiplexed, multispecies nuclear receptor assay for chemical hazard assessment
- (2020) Keith A. Houck et al. TOXICOLOGY IN VITRO
- Predicting Volume of Distribution in Humans: Performance of in silico Methods for A Large Set of Structurally Diverse Clinical Compounds
- (2020) Neha Murad et al. DRUG METABOLISM AND DISPOSITION
- Case study in 21 st century ecotoxicology: using in vitro aromatase inhibition data to predict short term in vivo responses in adult female fish
- (2020) Daniel L. Villeneuve et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase
- (2020) Jennifer H. Olker et al. TOXICOLOGY IN VITRO
- Non-targeted screening methodology to characterise human internal chemical exposure: Application to halogenated compounds in human milk
- (2020) Mariane Pourchet et al. TALANTA
- The next generation blueprint of computational toxicology at the U.S. Environmental Protection Agency
- (2019) Russell S Thomas et al. TOXICOLOGICAL SCIENCES
- Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays
- (2019) Timothy J Shafer et al. TOXICOLOGICAL SCIENCES
- High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition
- (2019) Jun Wang et al. ENVIRONMENT INTERNATIONAL
- Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment
- (2019) Edward J. Perkins et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- A Time-Embedding Network Models the Ontogeny of 23 Hepatic Drug Metabolizing Enzymes
- (2019) Matthew K. Matlock et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Using the concordance of in vitro and in vivo data to evaluate extrapolation assumptions
- (2019) Gregory S. Honda et al. PLoS One
- Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches
- (2019) Pamela D. Noyes et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library
- (2019) Katie Paul-Friedman et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment
- (2019) Anne Marie Gannon et al. FOOD AND CHEMICAL TOXICOLOGY
- Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization
- (2019) Katie Paul Friedman et al. TOXICOLOGICAL SCIENCES
- Profiling 58 compounds including cosmetic-relevant chemicals using ToxRefDB and ToxCast
- (2019) Ly L. Pham et al. FOOD AND CHEMICAL TOXICOLOGY
- Prioritizing chemicals of ecological concern in Great Lakes tributaries using high-throughput screening data and adverse outcome pathways
- (2019) Steven R. Corsi et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Comparative analysis of Rapid Equilibrium Dialysis (RED) and solid phase micro-extraction (SPME) methods for In Vitro-In Vivo extrapolation of environmental chemicals
- (2019) Kyle C. Ferguson et al. TOXICOLOGY IN VITRO
- Estimation of the Emission Characteristics of SVOCs from Household Articles Using Group Contribution Methods
- (2019) Cody K. Addington et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Development of a prioritization method for chemical-mediated effects on steroidogenesis using an integrated statistical analysis of high-throughput H295R data
- (2019) Derik E. Haggard et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay
- (2019) Tyler Beames et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
- (2019) Johanna Nyffeler et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Building predictive in vitro pulmonary toxicity assays using high-throughput imaging and artificial intelligence
- (2018) Jia-Ying Joey Lee et al. ARCHIVES OF TOXICOLOGY
- Suspect screening and non-targeted analysis of drinking water using point-of-use filters
- (2018) Seth R. Newton et al. ENVIRONMENTAL POLLUTION
- OrganoRelease – A framework for modeling the release of organic chemicals from the use and post-use of consumer products
- (2018) Mengya Tao et al. ENVIRONMENTAL POLLUTION
- Suspect Screening Analysis of Chemicals in Consumer Products
- (2018) Katherine A. Phillips et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Evaluation of an Air Quality Health Index for Predicting the Mutagenicity of Simulated Atmospheres
- (2018) Jose Zavala et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library
- (2018) Jun Wang et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Comparing Mechanistic and Preclinical Predictions of Volume of Distribution on a Large Set of Drugs
- (2018) Rosa Chan et al. PHARMACEUTICAL RESEARCH
- Differentiating Pathway-Specific From Nonspecific Effects in High-Throughput Toxicity Data: A Foundation for Prioritizing Adverse Outcome Pathway Development
- (2018) Kellie A Fay et al. TOXICOLOGICAL SCIENCES
- In vitro to in vivo extrapolation for high throughput prioritization and decision making
- (2018) Shannon M. Bell et al. TOXICOLOGY IN VITRO
- The US Federal Tox21 Program: A strategic and operational plan for continued leadership
- (2018) Russell Thomas ALTEX-Alternatives to Animal Experimentation
- OPERA models for predicting physicochemical properties and environmental fate endpoints
- (2018) Kamel Mansouri et al. Journal of Cheminformatics
- A new cell culture exposure system for studying the toxicity of volatile chemicals at the air–liquid interface
- (2018) Jose Zavala et al. INHALATION TOXICOLOGY
- Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments
- (2018) Elaine A. Cohen Hubal et al. Journal of Exposure Science and Environmental Epidemiology
- Predicting Fraction Unbound in Human Plasma from Chemical Structure: Improved Accuracy in the Low Value Ranges
- (2018) Reiko Watanabe et al. MOLECULAR PHARMACEUTICS
- OUP accepted manuscript
- (2018) TOXICOLOGICAL SCIENCES
- Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance
- (2018) Varvara Gouliarmou et al. TOXICOLOGY IN VITRO
- Evaluating biological activity of compounds by transcription factor activity profiling
- (2018) Alexander Medvedev et al. Science Advances
- Contaminants in bald eagles of the upper Midwestern U.S.: A framework for prioritizing future research based on in-vitro bioassays
- (2018) Sarah M. Elliott et al. ENVIRONMENTAL POLLUTION
- A Model for Risk-Based Screening and Prioritization of Human Exposure to Chemicals from Near-Field Sources
- (2018) Li Li et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Potential Toxicity of Complex Mixtures in Surface Waters from a Nationwide Survey of United States Streams: Identifying in Vitro Bioactivities and Causative Chemicals
- (2018) Brett R. Blackwell et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways
- (2018) Caroline L. Ring et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases
- (2018) Jennifer H Olker et al. TOXICOLOGICAL SCIENCES
- A combined quantitative property-property relationship (QPPR) for estimating packaging-food and solid material-water partition coefficients of organic compounds
- (2018) Lei Huang et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Trends in the application of high-resolution mass spectrometry for human biomonitoring: An analytical primer to studying the environmental chemical space of the human exposome
- (2017) Syam S. Andra et al. ENVIRONMENT INTERNATIONAL
- High-throughput dietary exposure predictions for chemical migrants from food contact substances for use in chemical prioritization
- (2017) Derya Biryol et al. ENVIRONMENT INTERNATIONAL
- Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability
- (2017) Caroline L. Ring et al. ENVIRONMENT INTERNATIONAL
- An “EAR” on Environmental Surveillance and Monitoring: A Case Study on the Use of Exposure–Activity Ratios (EARs) to Prioritize Sites, Chemicals, and Bioactivities of Concern in Great Lakes Waters
- (2017) Brett R. Blackwell et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library
- (2017) Nisha S. Sipes et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Improving substance information in USEtox® , part 2: Data for estimating fate and ecosystem exposure factors
- (2017) Erwan Saouter et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- High-throughput migration modelling for estimating exposure to chemicals in food packaging in screening and prioritization tools
- (2017) Alexi S. Ernstoff et al. FOOD AND CHEMICAL TOXICOLOGY
- High-throughput screening of chemicals as functional substitutes using structure-based classification models
- (2017) Katherine A. Phillips et al. GREEN CHEMISTRY
- Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA
- (2017) Jon R. Sobus et al. Journal of Exposure Science and Environmental Epidemiology
- Evaluation and calibration of high-throughput predictions of chemical distribution to tissues
- (2017) Robert G. Pearce et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- httk: R Package for High-Throughput Toxicokinetics
- (2017) Robert G. Pearce et al. Journal of Statistical Software
- On selecting a minimal set of in vitro assays to reliably determine estrogen agonist activity
- (2017) Richard S. Judson et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Embryonic vascular disruption adverse outcomes: Linking high throughput signaling signatures with functional consequences
- (2017) Robert G. Ellis-Hutchings et al. REPRODUCTIVE TOXICOLOGY
- Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity
- (2017) Tamara Tal et al. REPRODUCTIVE TOXICOLOGY
- Developing and applying metamodels of high resolution process-based simulations for high throughput exposure assessment of organic chemicals in riverine ecosystems
- (2017) M. Craig Barber et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity
- (2017) Michael W Hornung et al. TOXICOLOGICAL SCIENCES
- Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)
- (2017) Daniel R. Hallinger et al. TOXICOLOGY IN VITRO
- The CompTox Chemistry Dashboard: a community data resource for environmental chemistry
- (2017) Antony J. Williams et al. Journal of Cheminformatics
- Regulating temperature and relative humidity in air–liquid interface in vitro systems eliminates cytotoxicity resulting from control air exposures
- (2017) Jose Zavala et al. Toxicology Research
- ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology
- (2016) Ann M. Richard et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Development and Validation of a Computational Model for Androgen Receptor Activity
- (2016) Nicole C. Kleinstreuer et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring
- (2016) Julia E. Rager et al. ENVIRONMENT INTERNATIONAL
- Coupled near-field and far-field exposure assessment framework for chemicals in consumer products
- (2016) Peter Fantke et al. ENVIRONMENT INTERNATIONAL
- Environmental surveillance and monitoring-The next frontiers for high-throughput toxicology
- (2016) Anthony L. Schroeder et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Assessing the bioaccumulation potential of ionizable organic compounds: Current knowledge and research priorities
- (2016) James M. Armitage et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Informing the Human Plasma Protein Binding of Environmental Chemicals by Machine Learning in the Pharmaceutical Space: Applicability Domain and Limits of Predictability
- (2016) Brandall L. Ingle et al. Journal of Chemical Information and Modeling
- Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes
- (2016) Mark-Anthony Bray et al. Nature Protocols
- Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughputin vitroData, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling
- (2016) Jeremy A. Leonard et al. TOXICOLOGICAL SCIENCES
- Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards
- (2016) Hisham El-Masri et al. TOXICOLOGICAL SCIENCES
- Analysis of the Effects of Cell Stress and Cytotoxicity onIn VitroAssay Activity Across a Diverse Chemical and Assay Space
- (2016) Richard Judson et al. TOXICOLOGICAL SCIENCES
- Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries
- (2016) Katie Paul Friedman et al. TOXICOLOGICAL SCIENCES
- Toxicokinetic Triage for Environmental Chemicals
- (2015) John F. Wambaugh et al. TOXICOLOGICAL SCIENCES
- Integrated Model of Chemical Perturbations of a Biological Pathway Using 18In VitroHigh-Throughput Screening Assays for the Estrogen Receptor
- (2015) Richard S. Judson et al. TOXICOLOGICAL SCIENCES
- Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment
- (2015) Barbara A. Wetmore TOXICOLOGY
- Dose metric considerations in in vitro assays to improve quantitative in vitro–in vivo dose extrapolations
- (2015) Floris A. Groothuis et al. TOXICOLOGY
- Biokinetics in repeated-dosing in vitro drug toxicity studies
- (2015) Nynke I. Kramer et al. TOXICOLOGY IN VITRO
- Development of a Thyroperoxidase Inhibition Assay for High-Throughput Screening
- (2014) Katie B. Paul et al. CHEMICAL RESEARCH IN TOXICOLOGY
- SHEDS-HT: An Integrated Probabilistic Exposure Model for Prioritizing Exposures to Chemicals with Near-Field and Dietary Sources
- (2014) Kristin K. Isaacs et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Application of Mass Balance Models and the Chemical Activity Concept To Facilitate the Use of in Vitro Toxicity Data for Risk Assessment
- (2014) James M. Armitage et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- High Throughput Heuristics for Prioritizing Human Exposure to Environmental Chemicals
- (2014) John F. Wambaugh et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Development of a consumer product ingredient database for chemical exposure screening and prioritization
- (2014) M.-R. Goldsmith et al. FOOD AND CHEMICAL TOXICOLOGY
- Applying Adverse Outcome Pathways (AOPs) to support Integrated Approaches to Testing and Assessment (IATA)
- (2014) Knut Erik Tollefsen et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing
- (2014) Barbara A. Wetmore et al. TOXICOLOGICAL SCIENCES
- Measuring the exposome: A powerful basis for evaluating environmental exposures and cancer risk
- (2013) Christopher P. Wild et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Strategies to Characterize Polar Organic Contamination in Wastewater: Exploring the Capability of High Resolution Mass Spectrometry
- (2013) Emma L. Schymanski et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Multidimensional In Vivo Hazard Assessment Using Zebrafish
- (2013) Lisa Truong et al. TOXICOLOGICAL SCIENCES
- Relative Impact of Incorporating Pharmacokinetics on Predicting In Vivo Hazard and Mode of Action from High-Throughput In Vitro Toxicity Assays
- (2013) Barbara A. Wetmore et al. TOXICOLOGICAL SCIENCES
- PopGen: A virtual human population generator
- (2013) Kevin McNally et al. TOXICOLOGY
- Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management
- (2012) Robert Kavlock et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology
- (2012) A Rostami-Hodjegan CLINICAL PHARMACOLOGY & THERAPEUTICS
- Prioritizing Chemicals and Data Requirements for Screening-Level Exposure and Risk Assessment
- (2012) Jon A. Arnot et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Intake Fraction for the Indoor Environment: A Tool for Prioritizing Indoor Chemical Sources
- (2012) Hyeong-Moo Shin et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Rapid Methods to Estimate Potential Exposure to Semivolatile Organic Compounds in the Indoor Environment
- (2012) John C. Little et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- The exposome: from concept to utility
- (2012) Christopher Paul Wild INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model
- (2011) Arnaud Tonnelier et al. ARCHIVES OF TOXICOLOGY
- Zebrafish developmental screening of the ToxCast™ Phase I chemical library
- (2011) S. Padilla et al. REPRODUCTIVE TOXICOLOGY
- The exposure data landscape for manufactured chemicals
- (2011) Peter P. Egeghy et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment
- (2011) Barbara A. Wetmore et al. TOXICOLOGICAL SCIENCES
- Multimedia modeling of human exposure to chemical substances: The roles of food web biomagnification and biotransformation
- (2010) Jon A. Arnot et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Reverse engineering adverse outcome pathways
- (2010) Edward J. Perkins et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
- (2010) Gerald T. Ankley et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Xenobiotic-Metabolizing Enzyme and Transporter Gene Expression in Primary Cultures of Human Hepatocytes Modulated by Toxcast Chemicals
- (2010) Daniel M. Rotroff et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening
- (2010) Daniel M. Rotroff et al. TOXICOLOGICAL SCIENCES
- PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals
- (2010) Frédéric Y. Bois et al. TOXICOLOGY
- The Simcyp®Population-based ADME Simulator
- (2009) Masoud Jamei et al. Expert Opinion on Drug Metabolism & Toxicology
- Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds
- (2008) R. S. Obach et al. DRUG METABOLISM AND DISPOSITION
- USEtox—the UNEP-SETAC toxicity model: recommended characterisation factors for human toxicity and freshwater ecotoxicity in life cycle impact assessment
- (2008) Ralph K. Rosenbaum et al. INTERNATIONAL JOURNAL OF LIFE CYCLE ASSESSMENT
- Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment
- (2008) Robert J. Kavlock et al. RISK ANALYSIS
- The contribution of in vitro toxicity data in hazard and risk assessment: Current limitations and future perspectives
- (2008) Bas J. Blaauboer TOXICOLOGY LETTERS
- General approach for the calculation of tissue to plasma partition coefficients
- (2007) Walter Schmitt TOXICOLOGY IN VITRO
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now