HIF-1α and periodontitis: Novel insights linking host-environment interplay to periodontal phenotypes
出版年份 2023 全文链接
标题
HIF-1α and periodontitis: Novel insights linking host-environment interplay to periodontal phenotypes
作者
关键词
-
出版物
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
Volume 184, Issue -, Pages 50-78
出版商
Elsevier BV
发表日期
2023-09-26
DOI
10.1016/j.pbiomolbio.2023.09.002
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3‐D spheroids
- (2021) Marta H. G. Costa et al. Biotechnology Journal
- Vascular Endothelial Growth Factor: A Translational View in Oral Non-Communicable Diseases
- (2021) Sven Niklander et al. Biomolecules
- The Antioxidant Effect of Curcumin and Rutin on Oxidative Stress Biomarkers in Experimentally Induced Periodontitis in Hyperglycemic Wistar Rats
- (2021) Gilda M. Iova et al. MOLECULES
- The effect of hypoxia-mimicking responses on improving the regeneration of artificial vascular grafts
- (2021) Muhammad Rafique et al. BIOMATERIALS
- Hypoxia and Porphyromonas gingivalis-lipopolysaccharide synergistically induce NLRP3 inflammasome activation in human gingival fibroblasts
- (2021) Kai Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Cobalt doped nano-hydroxyapatite incorporated gum tragacanth-alginate beads as angiogenic-osteogenic cell encapsulation system for mesenchymal stem cell based bone tissue engineering
- (2021) Senthilguru Kulanthaivel et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Identification of Type H Vessels in Mice Mandibular Condyle
- (2021) H. Li et al. JOURNAL OF DENTAL RESEARCH
- Inhibiting PHD2 in human periodontal ligament cells via lentiviral vector‐mediated RNA interference facilitates cell osteogenic differentiation and periodontal repair
- (2021) Di Cui et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Notch‐1 and Notch‐3 Mediates Hypoxia‐Induced Synovial Fibroblasts Activation in Rheumatoid Arthritis
- (2021) Jianhai Chen et al. Arthritis & Rheumatology
- Competing endogenous RNA regulatory network of factor inhibiting HIF inhibitor as radioprotector for gastrointestinal toxicity via activating hypoxia-inducible factor-1 pathway
- (2021) Yu-wei Yang et al. Molecular Therapy-Nucleic Acids
- Reactive oxygen species can be traced locally and systemically in apical periodontitis: A systematic review
- (2021) A.C. Georgiou et al. ARCHIVES OF ORAL BIOLOGY
- Histochemical characteristics on minimodeling-based bone formation induced by anabolic drugs for osteoporotic treatment
- (2021) Tomomaya YAMAMOTO et al. BIOMEDICAL RESEARCH-TOKYO
- Overexpression of HIF ‐1α enhances the protective effect of mitophagy on steroid‐induced osteocytes apoptosis
- (2021) Ke Xu et al. ENVIRONMENTAL TOXICOLOGY
- Cynaroside prevents macrophage polarization into pro-inflammatory phenotype and alleviates cecal ligation and puncture-induced liver injury by targeting PKM2/HIF-1α axis
- (2021) Liuhua Pei et al. FITOTERAPIA
- PD-L1 Regulates Inflammation in LPS-Induced Lung Epithelial Cells and Vascular Endothelial Cells by Interacting with the HIF-1α Signaling Pathway
- (2021) Shilong Zhao et al. INFLAMMATION
- Biofabrication of vasculature in microphysiological models of bone
- (2021) Ian Whelan et al. Biofabrication
- Biomechanical and biological responses of periodontium in orthodontic tooth movement: up-date in a new decade
- (2021) Yuan Li et al. International Journal of Oral Science
- Chemically induced hypoxia by dimethyloxalylglycine (DMOG)-loaded nanoporous silica nanoparticles supports endothelial tube formation by sustained VEGF release from adipose tissue-derived stem cells
- (2021) Sarah Zippusch et al. Regenerative Biomaterials
- Mechanical loading and parathyroid hormone effects and synergism in bone vary by site and modeling/remodeling regime
- (2021) Samuel T. Robinson et al. BONE
- HIF-1α activator DMOG inhibits alveolar bone resorption in murine periodontitis by regulating macrophage polarization
- (2021) Mei-hua Chen et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Periodontitis Exacerbates Benign Prostatic Hyperplasia through Regulation of Oxidative Stress and Inflammation
- (2021) Cheng Fang et al. Oxidative Medicine and Cellular Longevity
- Immunomodulation in the Treatment of Periodontitis: Progress and Perspectives
- (2021) Bo Yang et al. Frontiers in Immunology
- Human osteoclast formation and resorptive function on biomineralized collagen
- (2021) Daniel de Melo Pereira et al. Bioactive Materials
- The hypoxic microenvironment: a driving force for heterotopic ossification progression
- (2020) Yifei Huang et al. Cell Communication and Signaling
- BMP9 Reduces Bone Loss in Ovariectomized Mice by Dual Regulation of Bone Remodeling
- (2020) Yan‐Man Zhou et al. JOURNAL OF BONE AND MINERAL RESEARCH
- HIF-1α Regulates Glucocorticoid-Induced Osteoporosis Through PDK1/AKT/mTOR Signaling Pathway
- (2020) Wen-Ning Xu et al. Frontiers in Endocrinology
- Endothelial Overexpression of Metallothionein Prevents Diabetes Mellitus-Induced Impairment in Ischemia Angiogenesis via Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells
- (2020) Kai Wang et al. DIABETES
- High levels of HIF-1ɑ in hypoxic dental pulps associated with teeth with severe periodontitis
- (2020) Xijiao Yu et al. JOURNAL OF MOLECULAR HISTOLOGY
- Diabetes as a potential risk for periodontitis: association studies
- (2020) Robert J. Genco et al. PERIODONTOLOGY 2000
- Effect of Chemically Induced Hypoxia on Osteogenic and Angiogenic Differentiation of Bone Marrow Mesenchymal Stem Cells and Human Umbilical Vein Endothelial Cells in Direct Coculture
- (2020) Van Thi Nguyen et al. Cells
- Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/ HIF-1α signaling
- (2020) Xujie Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- “Take My Bone Away?” Hypoxia and bone: A narrative review
- (2020) Scott S. Hannah et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Potential Bidirectional Relationship Between Periodontitis and Alzheimer’s Disease
- (2020) Daniela Liccardo et al. Frontiers in Physiology
- Hypoxia improved vasculogenesis in distraction osteogenesis through Mesenchymal-Epithelial transition (MET), Wnt/β-catenin signaling pathway, and autophagy
- (2020) Xuan He et al. ACTA HISTOCHEMICA
- Hypoxia in bone metastasis and osteolysis
- (2020) Vera M. Todd et al. CANCER LETTERS
- The Role of HIF in Immunity and Inflammation
- (2020) Anne F. McGettrick et al. Cell Metabolism
- PRKAR2B‐HIF‐1α loop promotes aerobic glycolysis and tumour growth in prostate cancer
- (2020) Lei Xia et al. CELL PROLIFERATION
- The role of HIF-1α in nicotine-induced root and bone resorption during orthodontic tooth movement
- (2020) Niklas Ullrich et al. EUROPEAN JOURNAL OF ORTHODONTICS
- An injectable hydrogel‐formulated inhibitor of prolyl‐4‐hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis
- (2020) Kosuke Nagai et al. FASEB JOURNAL
- Casticin suppresses monoiodoacetic acid-induced knee osteoarthritis through inhibiting HIF-1α/NLRP3 inflammasome signaling
- (2020) Xiaochen Li et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Periodontitis is an inflammatory disease of oxidative stress: We should treat it that way
- (2020) Fábio Sá Carneiro Sczepanik et al. PERIODONTOLOGY 2000
- Hypoxia Protects Rat Bone Marrow Mesenchymal Stem Cells Against Compression-Induced Apoptosis in the Degenerative Disc Microenvironment Through Activation of the HIF-1α/YAP Signaling Pathway
- (2020) Zhe Wang et al. STEM CELLS AND DEVELOPMENT
- Pathological angiogenesis and inflammation in tissues
- (2020) Ji-Hak Jeong et al. ARCHIVES OF PHARMACAL RESEARCH
- BMSC-Exosomes Carry Mutant HIF-1α for Improving Angiogenesis and Osteogenesis in Critical-Sized Calvarial Defects
- (2020) Chenting Ying et al. Frontiers in Bioengineering and Biotechnology
- Immunomodulatory effect of dimethyloxallyl glycine/nanosilicates-loaded fibrous structure on periodontal bone remodeling
- (2020) Zi-Qi Liu et al. Journal of Dental Sciences
- Constant hypoxia inhibits osteoclast differentiation and bone resorption by regulating phosphorylation of JNK and IκBα
- (2019) Zhenzhen Ma et al. INFLAMMATION RESEARCH
- HIF-1-Dependent Reprogramming of Glucose Metabolic Pathway of Cancer Cells and Its Therapeutic Significance
- (2019) Ayako Nagao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Hypoxia changes chemotaxis behaviour of mesenchymal stem cells via HIF-1α signalling
- (2019) Wei Xu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Hypoxia/pseudohypoxia‐mediated activation of hypoxia‐inducible factor‐1α in cancer
- (2019) Yoshihiro Hayashi et al. CANCER SCIENCE
- Hypoxia mimicking hydrogels to regulate the fate of transplanted stem cells
- (2019) Binulal N. Sathy et al. Acta Biomaterialia
- Digoxin Attenuates Receptor Activation of NF-κB Ligand-Induced Osteoclastogenesis in Macrophages
- (2019) Kimihiro Igari et al. JOURNAL OF VASCULAR RESEARCH
- Hypoxia inducible factors as mediators of reactive oxygen/nitrogen species homeostasis in physiological normoxia
- (2019) Jeffrey A. Stuart et al. MEDICAL HYPOTHESES
- Mechanisms of hypoxia signalling: new implications for nephrology
- (2019) Johannes Schödel et al. Nature Reviews Nephrology
- Proteomic analysis of human periodontal ligament cells under hypoxia
- (2019) Qiwen Li et al. Proteome Science
- Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
- (2019) Atsushi Tomokiyo et al. STEM CELLS AND DEVELOPMENT
- Porphyromonas gingivalis triggers inflammatory responses in periodontal ligament cells by succinate-succinate dehydrogenase–HIF–1α axis
- (2019) Wenqi Su et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Periodontitis and diabetes
- (2019) Philip M. Preshaw et al. BRITISH DENTAL JOURNAL
- Transforming growth factor-β1 and hypoxia inducible factor-1α synergistically inhibit the osteogenesis of periodontal ligament stem cells
- (2019) Zhihua Liu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The Regulation of Bone Metabolism and Disorders by Wnt Signaling
- (2019) Kazuhiro Maeda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Fusobacterium nucleatum Facilitates Apoptosis, ROS Generation, and Inflammatory Cytokine Production by Activating AKT/MAPK and NF-κB Signaling Pathways in Human Gingival Fibroblasts
- (2019) Wenyan Kang et al. Oxidative Medicine and Cellular Longevity
- Now a Nobel gas: oxygen
- (2019) Joachim Fandrey et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Rubidium-containing mesoporous bioactive glass scaffolds support angiogenesis, osteogenesis and antibacterial activity
- (2019) Xiang He et al. Materials Science & Engineering C-Materials for Biological Applications
- EPO could be regulated by HIF-1 and promote osteogenesis and accelerate bone repair
- (2019) Yijun Yu et al. Artificial Cells Nanomedicine and Biotechnology
- Advances in Hypoxia-Inducible Factor Biology
- (2018) Hani Choudhry et al. Cell Metabolism
- Repair of Critical-Sized Mandible Defects in Aged Rat Using Hypoxia Preconditioned BMSCs with Up-regulation of Hif-1α
- (2018) Jiankang Zhang et al. International Journal of Biological Sciences
- The Sealing Zone in Osteoclasts: A Self-Organized Structure on the Bone
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesoporous silicate nanoparticles/3D nanofibrous scaffold-mediated dual-drug delivery for bone tissue engineering
- (2018) Qingqing Yao et al. JOURNAL OF CONTROLLED RELEASE
- Activation of autophagy in periodontal ligament mesenchymal stem cells promotes angiogenesis in periodontitis
- (2018) Wei Wei et al. JOURNAL OF PERIODONTOLOGY
- Orthodontic tooth movement: The biology and clinical implications
- (2018) Yina Li et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- ARNT /HIF-1β links high-risk 1q21 gain and microenvironmental hypoxia to drug resistance and poor prognosis in multiple myeloma
- (2018) Chuan Wu et al. Cancer Medicine
- Role of HIF-1 in Cancer Progression: Novel Insights. A Review
- (2018) Aldo Pezzuto et al. CURRENT MOLECULAR MEDICINE
- Promoting vascularization for tissue engineering constructs: current strategies focusing on HIF-regulating scaffolds
- (2018) Tilman U. Esser et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Inhibition of the Oxygen Sensor PHD2 Enhances Tissue-Engineered Endochondral Bone Formation
- (2018) Pieter-Jan Stiers et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Mandibular osteotomy‐induced hypoxia enhances osteoclast activation and acid secretion by increasing glycolysis
- (2018) Yi Tang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Oral Microbiota Is Modified by Systemic Diseases
- (2018) D.T. Graves et al. JOURNAL OF DENTAL RESEARCH
- Gingival crevicular fluid and salivary HIF‐1α, VEGF, and TNF‐α levels in periodontal health and disease
- (2018) Beral Afacan et al. JOURNAL OF PERIODONTOLOGY
- Hypoxia-Inducible Factor (HIF)-1α Promotes Inflammation and Injury Following Aspiration-Induced Lung Injury in Mice
- (2018) Madathilparambil V. Suresh et al. SHOCK
- Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance
- (2018) Gaofeng Xiong et al. Nature Communications
- Concise Review: Periodontal Tissue Regeneration Using Stem Cells: Strategies and Translational Considerations
- (2018) Xin-Yue Xu et al. Stem Cells Translational Medicine
- Hypoxia-inducible factor-1α: a promising therapeutic target for autoimmune diseases
- (2017) Shi-Yang Guan et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Effect of prolyl hydroxylase inhibitor-loaded collagen barrier membranes on osteoclastogenesis and osteoblastogenesis
- (2017) Michael Edelmayer et al. JOURNAL OF BIOMATERIALS APPLICATIONS
- The many ways of osteoclast activation
- (2017) Joseph Lorenzo JOURNAL OF CLINICAL INVESTIGATION
- Skeletal energy homeostasis: a paradigm of endocrine discovery
- (2017) Karla J Suchacki et al. JOURNAL OF ENDOCRINOLOGY
- Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2
- (2017) Philippa A Hulley et al. JOURNAL OF PATHOLOGY
- Hypoxia-regulated human periodontal ligament cells via Wnt/β-catenin signaling pathway
- (2017) Zhili Xiao et al. MEDICINE
- Effects of deferoxamine on the osteogenic differentiation of human periodontal ligament cells
- (2017) Sen Mu et al. Molecular Medicine Reports
- Activation of NLRP3 inflammasome complex potentiates venous thrombosis in response to hypoxia
- (2017) Neha Gupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oxygen, Metabolism, and Regeneration: Lessons from Mice
- (2017) Ellen Heber-Katz TRENDS IN MOLECULAR MEDICINE
- Inhibiting PHD2 in bone marrow mesenchymal stem cells via lentiviral vector-mediated RNA interference facilitates the repair of periodontal tissue defects in SD rats
- (2017) Changxing Chen et al. Oncotarget
- L-mimosine and hypoxia can increase angiogenin production in dental pulp-derived cells
- (2017) Klara Janjić et al. BMC Oral Health
- Porphyromonas gingivalis-Derived Lipopolysaccharide Combines Hypoxia to Induce Caspase-1 Activation in Periodontitis
- (2017) Ran Cheng et al. Frontiers in Cellular and Infection Microbiology
- Hif-1α Overexpression Improves Transplanted Bone Mesenchymal Stem Cells Survival in Rat MCAO Stroke Model
- (2017) Bingke Lv et al. Frontiers in Molecular Neuroscience
- Evaluation of Salivary and Serum Antioxidant and Oxidative Stress Statuses in Patients with Chronic Periodontitis: A Case-Control Study
- (2017) Fatemeh Ahmadi-Motamayel et al. Frontiers in Physiology
- The Role of Reactive Oxygen Species and Autophagy in Periodontitis and Their Potential Linkage
- (2017) Chengcheng Liu et al. Frontiers in Physiology
- Hypoxia and Bone Metastatic Disease
- (2017) Rachelle W. Johnson et al. Current Osteoporosis Reports
- Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway
- (2017) Hui Kang et al. Frontiers in Immunology
- Metabolism Supports Macrophage Activation
- (2017) P. Kent Langston et al. Frontiers in Immunology
- Mitochondrial composition and function under the control of hypoxia
- (2017) Dominik C. Fuhrmann et al. Redox Biology
- Therapeutic potential of dental stem cells
- (2017) Elna Paul Chalisserry et al. Journal of Tissue Engineering
- Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways
- (2017) Karim Ullah et al. Scientific Reports
- Hypoxia-Mimicking Nanofibrous Scaffolds Promote Endogenous Bone Regeneration
- (2016) Qingqing Yao et al. ACS Applied Materials & Interfaces
- Hypoxia-mimicking Co doped TiO 2 microporous coating on titanium with enhanced angiogenic and osteogenic activities
- (2016) Jianhong Zhou et al. Acta Biomaterialia
- Compression and hypoxia play independent roles while having combinative effects in the osteoclastogenesis induced by periodontal ligament cells
- (2016) Mei Le Li et al. ANGLE ORTHODONTIST
- The effects of hypoxia on in vitro culture of dental-derived stem cells
- (2016) Stefanie Bressan Werle et al. ARCHIVES OF ORAL BIOLOGY
- HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival
- (2016) Steve Stegen et al. Cell Metabolism
- Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
- (2016) Johannes Schödel et al. EUROPEAN UROLOGY
- Hypoxia-inducible factor 1α-induced epithelial–mesenchymal transition of endometrial epithelial cells may contribute to the development of endometriosis
- (2016) Yao Xiong et al. HUMAN REPRODUCTION
- Energy metabolism in osteoclast formation and activity
- (2016) Silvia Lemma et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- The effects of hypoxia-inducible factor (HIF)-1α protein on bone regeneration during distraction osteogenesis: an animal study
- (2016) X. Jiang et al. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
- Deferoxamine released from poly(lactic-co-glycolic acid) promotes healing of osteoporotic bone defect via enhanced angiogenesis and osteogenesis
- (2016) Peng Jia et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Application of HIF-1α by gene therapy enhances angiogenesis and osteogenesis in alveolar bone defect regeneration
- (2016) Yang Zhang et al. JOURNAL OF GENE MEDICINE
- Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage
- (2016) Irina Ushach et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Hypoxia-inducible factor-1α inhibits interleukin-6 and -8 production in gingival epithelial cells during hypoxia
- (2016) M. Takedachi et al. JOURNAL OF PERIODONTAL RESEARCH
- The impact of Wnt signalling and hypoxia on osteogenic and cementogenic differentiation in human periodontal ligament cells
- (2016) Shuigen Li et al. Molecular Medicine Reports
- Expression of RUNX2 and MDM21 in rats with periodontitis under chronic intermittent hypoxia
- (2016) Kun Li et al. Asian Pacific Journal of Tropical Medicine
- Intermittent Hypoxia Influences Alveolar Bone Proper Microstructure via Hypoxia-Inducible Factor and VEGF Expression in Periodontal Ligaments of Growing Rats
- (2016) Shuji Oishi et al. Frontiers in Physiology
- Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer’s disease
- (2016) Ingar Olsen et al. Journal of Oral Microbiology
- HIF-1α regulates bone formation after osteogenic mechanical loading
- (2015) Ryan E. Tomlinson et al. BONE
- Bringing new life to damaged bone: The importance of angiogenesis in bone repair and regeneration
- (2015) Steve Stegen et al. BONE
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Factors secreted from dental pulp stem cells show multifaceted benefits for treating acute lung injury in mice
- (2015) Hirotaka Wakayama et al. CYTOTHERAPY
- Sirtuin 6 protects the heart from hypoxic damage
- (2015) Anna Maksin-Matveev et al. EXPERIMENTAL CELL RESEARCH
- Hypoxia signalling manipulation for bone regeneration
- (2015) Justin Drager et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin
- (2015) Colleen Wu et al. GENES & DEVELOPMENT
- Regenerative Medicine for Periodontal and Peri-implant Diseases
- (2015) L. Larsson et al. JOURNAL OF DENTAL RESEARCH
- Sirtuin 6 Modulates Hypoxia-induced Apoptosis in Osteoblasts via Inhibition of Glycolysis: Implication for Pathogenesis of Periapical Lesions
- (2015) Sang-Heng Kok et al. JOURNAL OF ENDODONTICS
- Emerging Regenerative Approaches for Periodontal Reconstruction: A Systematic Review From the AAP Regeneration Workshop
- (2015) Zhao Lin et al. JOURNAL OF PERIODONTOLOGY
- Hypoxia andP. gingivalisSynergistically Induce HIF-1 and NF-κB Activation in PDL Cells and Periodontal Diseases
- (2015) L. Gölz et al. MEDIATORS OF INFLAMMATION
- Progress on hypoxia-inducible factor-3: Its structure, gene regulation and biological function (Review)
- (2015) SHENG-LI YANG et al. Molecular Medicine Reports
- Recent Advances in Developing Inhibitors for Hypoxia-Inducible Factor Prolyl Hydroxylases and Their Therapeutic Implications
- (2015) So Kim et al. MOLECULES
- hCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κB-Mediated Inflammatory Responses
- (2015) Xiao Tang et al. Oxidative Medicine and Cellular Longevity
- Activation of HIFa Pathway in Mature Osteoblasts Disrupts the Integrity of the Osteocyte/Canalicular Network
- (2015) Gui-lai Zuo et al. PLoS One
- Hypoxia-inducible factor-1α antagonizes the hypoxia-mediated osteoblast cell viability reduction by inhibiting apoptosis
- (2015) GUICUN XU et al. Experimental and Therapeutic Medicine
- Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB
- (2015) Kamila Müller-Edenborn et al. Oncotarget
- Dental pulp-derived stem cell conditioned medium reduces cardiac injury following ischemia-reperfusion
- (2015) Satoshi Yamaguchi et al. Scientific Reports
- Redox regulation of FoxO transcription factors
- (2015) Lars-Oliver Klotz et al. Redox Biology
- HIF-1α pathway: role, regulation and intervention for cancer therapy
- (2015) Georgina N. Masoud et al. Acta Pharmaceutica Sinica B
- In vitro release of dimethyloxaloylglycine and l-mimosine from bovine bone mineral
- (2014) Hermann Agis et al. ARCHIVES OF ORAL BIOLOGY
- Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
- (2014) Zixue Jin et al. Cell Metabolism
- Engineering Adolescence
- (2014) Xiulan Yang et al. CIRCULATION RESEARCH
- Dimethyloxalylglycine lyophilized onto bone substitutes increase vessel area in rat calvarial defects
- (2014) Ulrike Kuchler et al. CLINICAL ORAL IMPLANTS RESEARCH
- HIF-1α inhibition blocks the cross talk between multiple myeloma plasma cells and tumor microenvironment
- (2014) Enrica Borsi et al. EXPERIMENTAL CELL RESEARCH
- Release kinetics of prolyl hydroxylase inhibitors from collagen barrier membranes
- (2014) Omar Hamid et al. JOURNAL OF BIOMATERIALS APPLICATIONS
- Global Burden of Severe Periodontitis in 1990-2010
- (2014) N.J. Kassebaum et al. JOURNAL OF DENTAL RESEARCH
- Effects of Hypoxia on the Immunomodulatory Properties of Human Gingiva–Derived Mesenchymal Stem Cells
- (2014) C.M. Jiang et al. JOURNAL OF DENTAL RESEARCH
- Lipid Peroxidation Levels and Total Oxidant/Antioxidant Status in Serum and Saliva From Patients With Chronic and Aggressive Periodontitis. Oxidative Stress Index: A New Biomarker for Periodontal Disease?
- (2014) Esra Baltacıoğlu et al. JOURNAL OF PERIODONTOLOGY
- Role of Anatomical Region and Hypoxia on Angiogenic Markers in Adipose-Derived Stromal Cells
- (2014) Jacob Rinkinen et al. JOURNAL OF RECONSTRUCTIVE MICROSURGERY
- Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
- (2014) Anjali P. Kusumbe et al. NATURE
- Dimethyloxalylglycine Prevents Bone Loss in Ovariectomized C57BL/6J Mice through Enhanced Angiogenesis and Osteogenesis
- (2014) Jia Peng et al. PLoS One
- Hypoxia induces osteogenic/angiogenic responses of bone marrow-derived mesenchymal stromal cells seeded on bone-derived scaffolds via ERK1/2 and p38 pathways
- (2013) Yi Zhou et al. BIOTECHNOLOGY AND BIOENGINEERING
- Deferoxamine expedites consolidation during mandibular distraction osteogenesis
- (2013) Alexis Donneys et al. BONE
- Cellular and molecular mechanisms in the hypoxic tissue: role of HIF-1 and ROS
- (2013) Andrea B. Zepeda et al. CELL BIOCHEMISTRY AND FUNCTION
- Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders
- (2013) Anu Kauppinen et al. CELLULAR SIGNALLING
- Angiogenic factors in bone local environment
- (2013) Shek Man Chim et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Inactivation ofVhlin Osteochondral Progenitor Cells Causes High Bone Mass Phenotype and Protects Against Age-Related Bone Loss in Adult Mice
- (2013) Tujun Weng et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
- (2013) Michael H. Rabinowitz JOURNAL OF MEDICINAL CHEMISTRY
- Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts
- (2013) Karl J Morten et al. JOURNAL OF PATHOLOGY
- The complexity of NF-κB signaling in inflammation and cancer
- (2013) Bastian Hoesel et al. Molecular Cancer
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- A Novel Prolyl Hydroxylase Inhibitor Protects Against Cell Death After Hypoxia
- (2013) Satoru Kontani et al. NEUROCHEMICAL RESEARCH
- Deferoxamine Administration Delivers Translational Optimization of Distraction Osteogenesis in the Irradiated Mandible
- (2013) Peter A. Felice et al. PLASTIC AND RECONSTRUCTIVE SURGERY
- Deferoxamine Restores Callus Size, Mineralization, and Mechanical Strength in Fracture Healing after Radiotherapy
- (2013) Alexis Donneys et al. PLASTIC AND RECONSTRUCTIVE SURGERY
- Antioxidative status of saliva before and after non-surgical periodontal treatment
- (2013) Nada Novakovic et al. Srpski Arhiv za Celokupno Lekarstvo
- Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potential
- (2013) Hao Ding et al. STEM CELLS AND DEVELOPMENT
- Hypoxia-based strategies for angiogenic induction
- (2013) Ektoras Hadjipanayi et al. Organogenesis
- Role of CCR2 in orthodontic tooth movement
- (2012) Silvana Rodrigues de Albuquerque Taddei et al. AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
- Deferoxamine reverses radiation induced hypovascularity during bone regeneration and repair in the murine mandible
- (2012) Aaron S. Farberg et al. BONE
- Localized deferoxamine injection augments vascularity and improves bony union in pathologic fracture healing after radiotherapy
- (2012) Alexis Donneys et al. BONE
- The HIF Signaling Pathway in Osteoblasts Directly Modulates Erythropoiesis through the Production of EPO
- (2012) Erinn B. Rankin et al. CELL
- Hypoxia induces apoptosis and autophagic cell death in human periodontal ligament cells through HIF-1α pathway
- (2012) Z.-C. Song et al. CELL PROLIFERATION
- Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells
- (2012) Yoshihide Shimojo et al. CLINICAL & EXPERIMENTAL METASTASIS
- GNAS1 and PHD2 Short-interfering RNA Support Bone Regeneration in Vitro and in an in Vivo Sheep Model
- (2012) Carmen N. Ríos et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- Increased Proliferation and Analysis of Differential Gene Expression in Human Wharton's Jelly-derived Mesenchymal Stromal Cells under Hypoxia
- (2012) Usha Nekanti et al. International Journal of Biological Sciences
- Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc
- (2012) Nobuyuki Fujita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential in vitro and cellular effects of iron chelators for hypoxia inducible factor hydroxylases
- (2012) Eun A. Cho et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH)
- (2012) Shannon C. Flagg et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study
- (2012) Weibin Zhang et al. JOURNAL OF ORTHOPAEDIC SCIENCE
- Nicotine and lipopolysaccharide stimulate the production of MMPs and prostaglandin E2by hypoxia-inducible factor-1α up-regulation in human periodontal ligament cells
- (2012) Y-S. Kim et al. JOURNAL OF PERIODONTAL RESEARCH
- Inhibition of Transforming Growth Factor β1/Smad3 Signaling Decreases Hypoxia-Inducible Factor-1α Protein Stability by Inducing Prolyl Hydroxylase 2 Expression in Human Periodontal Ligament Cells
- (2012) Teppei Watanabe et al. JOURNAL OF PERIODONTOLOGY
- Hypoxia triggers a HIF-mediated differentiation of peripheral blood mononuclear cells into osteoclasts
- (2012) T. C. Dandajena et al. Orthodontics & Craniofacial Research
- Systemic Preconditioning by a Prolyl Hydroxylase Inhibitor Promotes Prevention of Skin Flap Necrosis via HIF-1-Induced Bone Marrow-Derived Cells
- (2012) Mitsuru Takaku et al. PLoS One
- Synergistic Inhibition of Wnt Pathway by HIF-1α and Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts
- (2012) Dafu Chen et al. PLoS One
- Energy metabolism and rheumatic diseases: from cell to organism
- (2012) Cornelia M Spies et al. ARTHRITIS RESEARCH & THERAPY
- The therapeutic potential of oxygen tension manipulation via hypoxia inducible factors and mimicking agents in guided bone regeneration. A review
- (2011) Anastasios A. Mamalis et al. ARCHIVES OF ORAL BIOLOGY
- Detection of bacterial diversity in rat's periodontitis model under imitational altitude hypoxia environment
- (2011) Xian Xiao et al. ARCHIVES OF ORAL BIOLOGY
- Repairing critical-sized calvarial defects with BMSCs modified by a constitutively active form of hypoxia-inducible factor-1α and a phosphate cement scaffold
- (2011) Duohong Zou et al. BIOMATERIALS
- Blood vessel formation in the tissue-engineered bone with the constitutively active form of HIF-1α mediated BMSCs
- (2011) Duohong Zou et al. BIOMATERIALS
- Mice with increased angiogenesis and osteogenesis due to conditional activation of HIF pathway in osteoblasts are protected from ovariectomy induced bone loss
- (2011) Qiang Zhao et al. BONE
- NFκB and HIF display synergistic behaviour during hypoxic inflammation
- (2011) Ulrike Bruning et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Transcriptional Regulation of Vascular Endothelial Growth Factor (VEGF) by Osteoblast-specific Transcription Factor Osterix (Osx) in Osteoblasts
- (2011) Wanjin Tang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia
- (2011) Eiichi Hinoi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Bone remodelling at a glance
- (2011) J. C. Crockett et al. JOURNAL OF CELL SCIENCE
- Increasing Vascularity to Improve Healing of a Segmental Defect of the Rat Femur
- (2011) Rena Stewart et al. JOURNAL OF ORTHOPAEDIC TRAUMA
- Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts
- (2011) H. Agis et al. JOURNAL OF PERIODONTAL RESEARCH
- Lipopolysaccharide and Hypoxia-Induced HIF-1 Activation in Human Gingival Fibroblasts
- (2011) Jing-Ping Li et al. JOURNAL OF PERIODONTOLOGY
- Hypoxia inducible factor-1α directly induces the expression of receptor activator of nuclear factor-κB ligand in periodontal ligament fibroblasts
- (2011) Hyun-Jung Park et al. MOLECULES AND CELLS
- Molecular mechanisms and clinical applications of angiogenesis
- (2011) Peter Carmeliet et al. NATURE
- PI3K and ERK-Induced Rac1 Activation Mediates Hypoxia-Induced HIF-1α Expression in MCF-7 Breast Cancer Cells
- (2011) Jun Du et al. PLoS One
- Repair of Critical-Sized Rat Calvarial Defects Using Genetically Engineered BMSCs Overexpressing HIF-1α
- (2011) Duohong Zou et al. STEM CELLS
- Intracellular metabolic pathways control immune tolerance
- (2011) Claudio Procaccini et al. TRENDS IN IMMUNOLOGY
- Role of HIF-1α in skeletal development
- (2010) Chao Wan et al. Annals of the New York Academy of Sciences
- Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells
- (2010) Christina Holzwarth et al. BMC CELL BIOLOGY
- The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
- (2010) Lei Zhong et al. CELL
- Hypoxia stimulates osteoclast formation from human peripheral blood
- (2010) Jennifer C. Utting et al. CELL BIOCHEMISTRY AND FUNCTION
- Crosstalk of reactive oxygen species and NF-κB signaling
- (2010) Michael J Morgan et al. CELL RESEARCH
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia
- (2010) Lin Yan et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Imatinib mesylate induces clinical remission in rheumatoid arthritis
- (2010) Ivânio Pereira et al. JOINT BONE SPINE
- Inhibition of osteoclastogenesis by prolyl hydroxylase inhibitor dimethyloxallyl glycine
- (2010) Andrew J. Leger et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Chronic Inhibition of Hypoxia-inducible Factor Prolyl 4-hydroxylase Improves Ventricular Performance, Remodeling, and Vascularity After Myocardial Infarction in the Rat
- (2010) Weike Bao et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- VEGF-A expression in osteoclasts is regulated by NF-κB induction of HIF-1α
- (2010) Diana P. Trebec-Reynolds et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Hypoxia induces BMP-2 expression via ILK, Akt, mTOR, and HIF-1 pathways in osteoblasts
- (2010) Wen-Pei Tseng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Expression of Hypoxia-Inducible Factor-1α in Human Periodontal Tissue
- (2010) King-Tung Ng et al. JOURNAL OF PERIODONTOLOGY
- Effects of Enamel Matrix Derivative on Vascular Endothelial Growth Factor Expression and Microvessel Density in Gingival Tissues of Periodontal Pocket: A Comparative Study
- (2010) Simone Domenico Aspriello et al. JOURNAL OF PERIODONTOLOGY
- The Role of Psychologic Stress-Induced Hypoxia-Inducible Factor-1α in Rat Experimental Periodontitis
- (2010) Shiguang Huang et al. JOURNAL OF PERIODONTOLOGY
- HIF-1 and HIF-2 transcription factors — Similar but not identical
- (2010) Agnieszka Loboda et al. MOLECULES AND CELLS
- Cycling hypoxia increases U87 glioma cell radioresistance via ROS induced higher and long-term HIF-1 signal transduction activity
- (2010) Hsieh ONCOLOGY REPORTS
- Analysis of gene expression profiles in human periodontal ligament cells under hypoxia: The protective effect of CC chemokine ligand 2 to oxygen shortage
- (2009) Yukiko Kitase et al. ARCHIVES OF ORAL BIOLOGY
- Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1α
- (2009) Dong Hoon Shin et al. FEBS Journal
- Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway
- (2009) Nobuko Koshikawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-inducible factors 1α and 2α exert both distinct and overlapping functions in long bone development
- (2009) Stacy H. Shomento et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice
- (2009) Xing Shen et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Acute hypoxia and osteoclast activity: a balance between enhanced resorption and increased apoptosis
- (2009) Helen J Knowles et al. JOURNAL OF PATHOLOGY
- Recent progress in the biology and physiology of sirtuins
- (2009) Toren Finkel et al. NATURE
- LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner
- (2008) Kenichiro Nishi et al. ANTIOXIDANTS & REDOX SIGNALING
- Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
- (2008) Adam T. Boutin et al. CELL
- NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism
- (2008) Antonios O. Aliprantis et al. JOURNAL OF CLINICAL INVESTIGATION
- Critical Role of HIF-1α in Keratinocyte Defense against Bacterial Infection
- (2008) Carole Peyssonnaux et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte–osteoclast differentiation via induction of VEGF
- (2008) HJ Knowles et al. JOURNAL OF PATHOLOGY
- Cellular responses of rat periodontal ligament cells under hypoxia and re-oxygenation conditions in vitro
- (2008) H. Amemiya et al. JOURNAL OF PERIODONTAL RESEARCH
- Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury
- (2008) P. Hill et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia
- (2008) Aline Bozec et al. NATURE
- NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
- (2008) Jordi Rius et al. NATURE
- Activation of the hypoxia-inducible factor-1 pathway accelerates bone regeneration
- (2008) C. Wan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of hypoxia-inducible factor-1 in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes
- (2008) J. K. Ahn et al. RHEUMATOLOGY
- Enhanced Angiogenesis in Porous Collagen–Chitosan Scaffolds Loaded with Angiogenin
- (2008) Haifei Shi et al. TISSUE ENGINEERING PART A
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More