Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway

Increase in gene dosage is a mechanism of HIF-1α constitutive expression in head and neck squamous cell carcinomas

(2009) Pablo Secades et al.   GENES CHROMOSOMES & CANCER

A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis

(2009) J. S. Park et al.   HUMAN MOLECULAR GENETICS

HDAC family: What are the cancer relevant targets?

(2008) Olaf Witt et al.   CANCER LETTERS

Mitochondrial Cytochrome B Gene Mutation Promotes Tumor Growth in Bladder Cancer

(2008) S. Dasgupta et al.   CANCER RESEARCH

Mitochondrial complex III regulates hypoxic activation of HIF

(2008) T Klimova et al.   CELL DEATH AND DIFFERENTIATION

Hypoxia-inducible factor 1 and cancer pathogenesis

(2008) Gregg L. Semenza   IUBMB LIFE

ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis

(2008) K. Ishikawa et al.   SCIENCE

Regulation of cancer cell metabolism by hypoxia-inducible factor 1

(2008) Gregg L. Semenza   SEMINARS IN CANCER BIOLOGY

Lipopolysaccharide induces hypoxia-inducible factor-1 alpha mRNA expression and activation via NADPH oxidase and Sp1-dependent pathway in BV2 murine microglial cells

(2007) Young Taek Oh et al.   NEUROSCIENCE LETTERS