Mechanism investigation of Duhuo Jisheng pill against rheumatoid arthritis based on a strategy for the integration of network pharmacology, molecular docking and in vivo experimental verification

Bioactive compounds from four Indian medicinal plants have different potency to induce sex reversal in Nile tilapia: A chromatographic, molecular docking and in silico analysis

(2023) Debosree Mukherjee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Confirmation of inhibitingTLR4/MyD88/NF-κB Signalling Pathway by Duhuo Jisheng Decoction on Osteoarthritis: A Network Pharmacology Approach-Integrated Experimental Study

(2022) Linglong Liu et al.   Frontiers in Pharmacology

Integrated Network Pharmacology and Comprehensive Bioinformatics Identifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula for Treatment of Comorbidity With Alzheimer’s Disease and Depression

(2022) Tingting Zhang et al.   Frontiers in Pharmacology

An overview on applications of SwissADME web tool in the design and development of anticancer, antitubercular and antimicrobial agents: A medicinal chemist's perspective

(2022) Bulti Bakchi et al.   JOURNAL OF MOLECULAR STRUCTURE

NCAPG Promotes Pulmonary Artery Smooth Muscle Cell Proliferation as a Promising Therapeutic Target of Idiopathic Pulmonary Hypertension: Bioinformatics Analysis and Experiment Verification

(2022) Bowen Fu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical evidence construction of East Asian herbal medicine for inflammatory pain in rheumatoid arthritis based on integrative data mining approach

(2022) Hee-Geun Jo et al.   PHARMACOLOGICAL RESEARCH

TCMSID: a simplified integrated database for drug discovery from traditional chinese medicine

(2022) Liu-Xia Zhang et al.   Journal of Cheminformatics

Tomatidine Suppresses the Destructive Behaviors of Fibroblast-Like Synoviocytes and Ameliorates Type II Collagen-Induced Arthritis in Rats

(2021) Xiaolu Yu et al.   Frontiers in Pharmacology

Naringenin nanocrystals for improving anti-rheumatoid arthritis activity

(2021) Guangshuai Zhang et al.   Asian Journal of Pharmaceutical Sciences

Traditional herbal medicine: Therapeutic potential in rheumatoid arthritis

(2021) Yuan Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The role of JAK/STAT signaling pathway and its inhibitors in diseases

(2020) Ping Xin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

MicroRNA-26b relieves inflammatory response and myocardial remodeling of mice with myocardial infarction by suppression of MAPK pathway through binding to PTGS2

(2019) Zhen-Wei Ge et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Melatonin attenuates TNF-α and IL-1β expression in synovial fibroblasts and diminishes cartilage degradation: implications for the treatment of rheumatoid arthritis

(2019) Chien-Chung Huang et al.   JOURNAL OF PINEAL RESEARCH

ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome

(2019) Xiwen Dong et al.   Cellular & Molecular Immunology

Micheliolide Protects Against Doxorubicin-Induced Cardiotoxicity in Mice by Regulating PI3K/Akt/NF-kB Signaling Pathway

(2019) Ashkan Kalantary-Charvadeh et al.   Cardiovascular Toxicology

Interleukin-6 and tumour necrosis factor-α cooperatively promote cell cycle regulators and proliferate rheumatoid arthritis fibroblast-like synovial cells

(2019) K Kaneshiro et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Correlation between albumin to fibrinogen ratio, C-reactive protein to albumin ratio and Th17 cells in patients with rheumatoid arthritis

(2019) Yujue He et al.   CLINICA CHIMICA ACTA

Up-regulation of miR-365 promotes the apoptosis and restrains proliferation of synoviocytes through downregulation of IGF1 and the inactivation of the PI3K/AKT/mTOR pathway in mice with rheumatoid arthritis

(2019) Xiaojun Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model

(2019) Wei Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect

(2018) Yan Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Salicin from Alangium chinense Ameliorates Rheumatoid Arthritis by Modulating the Nrf2-HO-1-ROS Pathways

(2018) Ke-feng Zhai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Follistatin-like protein 1 induction of matrix metalloproteinase 1, 3 and 13 gene expression in rheumatoid arthritis synoviocytes requires MAPK, JAK/STAT3 and NF-κB pathways

(2018) Su Ni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Metabolomic Analysis of Biochemical Changes in the Serum and Urine of Freund’s Adjuvant-Induced Arthritis in Rats after Treatment with Silkworm Excrement

(2018) Tianyao Zheng et al.   MOLECULES

Glycyrrhizic acid from licorice down-regulates inflammatory responses via blocking MAPKs and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation

(2018) Wenfeng Liu et al.   MedChemComm

4-(Hydroxymethyl)catechol Extracted From Fungi in Marine Sponges Attenuates Rheumatoid Arthritis by Inhibiting PI3K/Akt/NF-κB Signaling

(2018) Jong Y. Lee et al.   Frontiers in Pharmacology

Analysis of miRNA expression in patients with rheumatoid arthritis during remission and relapse after a 5-year trial of tofacitinib treatment

(2018) Julio C. Fernández-Ruiz et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Sinomenine Inhibits the Progression of Rheumatoid Arthritis by Regulating the Secretion of Inflammatory Cytokines and Monocyte/Macrophage Subsets

(2018) Weiwei Liu et al.   Frontiers in Immunology

Enhanced neutrophil autophagy and increased concentrations of IL-6, IL-8, IL-10 and MCP-1 in rheumatoid arthritis

(2018) Qiyuan An et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

ETCM: an encyclopaedia of traditional Chinese medicine

(2018) Hai-Yu Xu et al.   NUCLEIC ACIDS RESEARCH

Immunopathogenesis of Rheumatoid Arthritis

(2017) Gary S. Firestein et al.   IMMUNITY

The protective effects of curculigoside A on adjuvant-induced arthritis by inhibiting NF-кB/NLRP3 activation in rats

(2016) Huimin Ding et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Evidence of Chinese herbal medicine Duhuo Jisheng decoction for knee osteoarthritis: a systematic review of randomised clinical trials

(2016) Wenming Zhang et al.   BMJ Open

CytoNCA: A cytoscape plugin for centrality analysis and evaluation of protein interaction networks

(2015) Yu Tang et al.   BIOSYSTEMS

Low-Molecular-Weight Fucoidan Inhibits the Viability and Invasiveness and Triggers Apoptosis in IL-1β-Treated Human Rheumatoid Arthritis Fibroblast Synoviocytes

(2015) Zunhua Shu et al.   INFLAMMATION

Cucurbitacin E inhibits TNF-α-induced inflammatory cytokine production in human synoviocyte MH7A cells via suppression of PI3K/Akt/NF-κB pathways

(2015) Qingyun Jia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting of proangiogenic signalling pathways in chronic inflammation

(2015) Sander W. Tas et al.   Nature Reviews Rheumatology

Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies

(2015) Sahil Gambhir et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Bufalin Exerts Inhibitory Effects on IL-1β-Mediated Proliferation and Induces Apoptosis in Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes

(2014) Yue-wen Chang et al.   INFLAMMATION

Therapeutic effect of Captopril on rheumatoid arthritis in rats

(2014) Hong-Mei Liu et al.   Asian Pacific Journal of Tropical Medicine

Increased Th17 Cell Frequency and Poor Clinical Outcome in Rheumatoid Arthritis Are Associated With a Genetic Variant in theIL4RGene, rs1805010

(2014) Jan Leipe et al.   Arthritis & Rheumatology

EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-κB andMKK7/JNK/AP-1 signaling

(2010) Balachandar Venkatesan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT

Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast – like synoviocytes of collagen induced arthritic rats

(2008) L.-L. Zhang et al.   INFLAMMATION RESEARCH