Micheliolide Protects Against Doxorubicin-Induced Cardiotoxicity in Mice by Regulating PI3K/Akt/NF-kB Signaling Pathway

Micheliolide alleviates hepatic steatosis in db/db mice by inhibiting inflammation and promoting autophagy via PPAR-γ-mediated NF-кB and AMPK/mTOR signaling

(2018) Juan Zhong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity?

(2018) Jenelle Govender et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Toxicological study of a new doxorubicin-loaded pH-sensitive liposome: A preclinical approach

(2018) Juliana de Oliveira Silva et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Enoxaparin attenuates doxorubicin induced cardiotoxicity in rats via interfering with oxidative stress, inflammation and apoptosis

(2018) Reem Ali Shaker et al.   BMC Pharmacology & Toxicology

Apigenin Attenuates Adriamycin-Induced Cardiomyocyte Apoptosis via the PI3K/AKT/mTOR Pathway

(2017) Wei Yu et al.   Evidence-based Complementary and Alternative Medicine

MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation

(2017) Qingwen Zhang et al.   MEDIATORS OF INFLAMMATION

Oxidative Stress and Cellular Response to Doxorubicin: A Common Factor in the Complex Milieu of Anthracycline Cardiotoxicity

(2017) Donato Cappetta et al.   Oxidative Medicine and Cellular Longevity

An Alpha-1A Adrenergic Receptor Agonist Prevents Acute Doxorubicin Cardiomyopathy in Male Mice

(2017) Megan D. Montgomery et al.   PLoS One

Doxorubicin-induced oxidative stress: The protective effect of nicorandil on HL-1 cardiomyocytes

(2017) Mari C. Asensio-López et al.   PLoS One

Micheliolide suppresses LPS-induced neuroinflammatory responses

(2017) Zhaomeng Sun et al.   PLoS One

HHX-5, a derivative of sesquiterpene from Chinese agarwood, suppresses innate and adaptive immunity via inhibiting STAT signaling pathways

(2016) Zhixiang Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Artesunate alleviates hepatic fibrosis induced by multiple pathogenic factors and inflammation through the inhibition of LPS/TLR4/NF-κB signaling pathway in rats

(2015) Lina Lai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer

(2015) Solomon K.S. Amoah et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chrysin alleviates acute doxorubicin cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

(2014) Eman M. Mantawy et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer

(2014) Emilie Viennois et al.   LABORATORY INVESTIGATION

AstragalusPolysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways

(2014) Yuan Cao et al.   Oxidative Medicine and Cellular Longevity

Manipulation of Cardiac Phosphatidylinositol 3-Kinase (PI3K)/Akt Signaling by Apoptosis Regulator through Modulating IAP Expression (ARIA) Regulates Cardiomyocyte Death during Doxorubicin-induced Cardiomyopathy

(2013) Youhei Kitamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

(2013) RUN-MIN GUO et al.   Molecular Medicine Reports

Imatinib Reverses Doxorubicin Resistance by Affecting Activation of STAT3-Dependent NF-κB and HSP27/p38/AKT Pathways and by Inhibiting ABCB1

(2013) Jonathan T. Sims et al.   PLoS One

Regulation of NF-κB Activation through a Novel PI-3K-Independent and PKA/Akt-Dependent Pathway in Human Umbilical Vein Endothelial Cells

(2012) Sakshi Balwani et al.   PLoS One

Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia Mangostana

(2010) J. Tangpong et al.   NEUROSCIENCE

Direct effects of doxorubicin on skeletal muscle contribute to fatigue

(2009) K van Norren et al.   BRITISH JOURNAL OF CANCER

Akt-mediated regulation of NFκB and the essentialness of NFκB for the oncogenicity of PI3K and Akt

(2009) Dong Bai et al.   INTERNATIONAL JOURNAL OF CANCER