FoxO1 knockdown inhibits RANKL‐induced osteoclastogenesis by blocking NLRP3 inflammasome activation

FoxO1/NLRP3 Inflammasome Promotes Age-Related Alveolar Bone Resorption

(2023) Z. Wang et al.   JOURNAL OF DENTAL RESEARCH

Artesunate ameliorates ligature-induced periodontitis by attenuating NLRP3 inflammasome-mediated osteoclastogenesis and enhancing osteogenic differentiation

(2023) Zhanqi Wang et al.   International Immunopharmacology

CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling

(2022) Caojie Liu et al.   Nature Communications

Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling transduction

(2022) Weijia Sun et al.   Nature Communications

AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection

(2022) Pin Wan et al.   Virulence

FOXO1 differentially regulates bone formation in young and aged mice

(2022) Yi Xiong et al.   CELLULAR SIGNALLING

A20 inhibits periodontal bone resorption and NLRP3-mediated M1 macrophage polarization

(2022) Liguang Hou et al.   EXPERIMENTAL CELL RESEARCH

Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice

(2022) Shanshan Li et al.   Cell Reports

The NLRP3 inflammasome: regulation by metabolic signals

(2022) Antoni Olona et al.   TRENDS IN IMMUNOLOGY

PERK signaling pathway in bone metabolism: Friend or foe?

(2021) Jiachao Guo et al.   CELL PROLIFERATION

Inflammasomes and adaptive immune responses

(2021) Katherine A. Deets et al.   NATURE IMMUNOLOGY

NLRP3 inflammasome activation and cell death

(2021) Yi Huang et al.   Cellular & Molecular Immunology

Cell biology of inflammasome activation

(2021) Abhimanu Pandey et al.   TRENDS IN CELL BIOLOGY

Inflammasomes in Alveolar Bone Loss

(2021) Yang Li et al.   Frontiers in Immunology

FOXOs: masters of the equilibrium

(2021) Tianshu Gui et al.   FEBS Journal

Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways

(2021) Huaqiang Tao et al.   PHARMACOLOGICAL RESEARCH

The Roles of FoxO Transcription Factors in Regulation of Bone Cells Function

(2020) Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Global, Regional, and National Levels and Trends in Burden of Oral Conditions from 1990 to 2017: A Systematic Analysis for the Global Burden of Disease 2017 Study

(2020) et al.   JOURNAL OF DENTAL RESEARCH

Regulation of Runx2 by post-translational modifications in osteoblast differentiation

(2020) K. Gomathi et al.   LIFE SCIENCES

Looking down on NF-κB

(2020) Leah M. Williams et al.   MOLECULAR AND CELLULAR BIOLOGY

NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation

(2020) Yuyi Chen et al.   CELL PROLIFERATION

CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling

(2020) Shun Xu et al.   Clinical and Translational Medicine

Activation of ROS/MAPKs/NF-κB/NLRP3 and inhibition of efferocytosis in osteoclast-mediated diabetic osteoporosis

(2019) Yanan An et al.   FASEB JOURNAL

NF-κB Signaling Regulates Physiological and Pathological Chondrogenesis

(2019) Eijiro Jimi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation

(2016) C Wang et al.   Cell Death & Disease

ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β

(2016) Agnieszka Robaszkiewicz et al.   Scientific Reports

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

Redox regulation of FoxO transcription factors

(2015) Lars-Oliver Klotz et al.   Redox Biology

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

(2014) Shoshana M. Bartell et al.   Nature Communications

Optimization of the ligature-induced periodontitis model in mice

(2013) Toshiharu Abe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Celebrating 25 years of NF-κB research

(2012) Sankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response

(2012) Jaya Sangodkar et al.   JOURNAL OF CLINICAL INVESTIGATION

FoxO1 Is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

(2010) Marie-Therese Rached et al.   Cell Metabolism

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

FoxO1 Links Insulin Resistance to Proinflammatory Cytokine IL-1  Production in Macrophages

(2009) D. Su et al.   DIABETES

The Pivotal Role of the Alternative NF-κB Pathway in Maintenance of Basal Bone Homeostasis and Osteoclastogenesis

(2009) Niroshani S Soysa et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The EGFR network in bone biology and pathology

(2009) Marlon R. Schneider et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

NF-κB modulators in osteolytic bone diseases

(2008) Jiake Xu et al.   CYTOKINE & GROWTH FACTOR REVIEWS

RelB is the NF- B subunit downstream of NIK responsible for osteoclast differentiation

(2008) S. Vaira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA