Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR

(2011) Trever G. Bivona et al.   NATURE

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors

(2011) L. V. Sequist et al.   Science Translational Medicine

Inferring dynamic gene networks under varying conditions for transcriptomic network comparison

(2010) Teppei Shimamura et al.   BIOINFORMATICS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Combination Treatment with MEK and AKT Inhibitors Is More Effective than Each Drug Alone in Human Non-Small Cell Lung Cancer In Vitro and In Vivo

(2010) Jieru Meng et al.   PLoS One

PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR

(2009) M. L. Sos et al.   CANCER RESEARCH

Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non-Small-Cell Lung Cancer

(2009) J. Yu et al.   CLINICAL CANCER RESEARCH

Targeted reduction of KLF6-SV1 restores chemotherapy sensitivity in resistant lung adenocarcinoma

(2009) Jaya Sangodkar et al.   LUNG CANCER

Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFκB transcription factors

(2008) Jolyon Terragni et al.   BMC CELL BIOLOGY

The role of KLF6 and its splice variants in cancer therapy

(2008) Analisa DiFeo et al.   DRUG RESISTANCE UPDATES

Ras Promotes Growth by Alternative Splicing-Mediated Inactivation of the KLF6 Tumor Suppressor in Hepatocellular Carcinoma

(2008) Steven Yea et al.   GASTROENTEROLOGY

PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer

(2008) C J Guigon et al.   ONCOGENE