Evaluation of chemical constituents of Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia) as adenosine A1/A2A receptor ligands

Research progress on adenosine in central nervous system diseases

(2019) Ying‐Jiao Liu et al.   CNS Neuroscience & Therapeutics

The Role of Adenosine Receptors in Mood and Anxiety Disorders

(2019) Dietrich van Calker et al.   JOURNAL OF NEUROCHEMISTRY

Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors

(2019) Tae-Ho Kim et al.   Biomolecules & Therapeutics

A Beneficial Role of Rooibos in Diabetes Mellitus: A Systematic Review and Meta-Analysis

(2018) Moe Sasaki et al.   MOLECULES

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

A BOILED-Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

(2016) Antoine Daina et al.   ChemMedChem

Tea consumption reduces the incidence of neurocognitive disorders: Findings from the Singapore longitudinal aging study

(2016) L. Feng et al.   Journal of Nutrition Health & Aging

1,3,7-Triethyl-substituted xanthines—possess nanomolar affinity for the adenosine A1 receptor

(2015) Mietha M. Van der Walt et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors

(2015) Mohamad Wessam Alnouri et al.   Purinergic Signalling

Adenosine Receptors: Expression, Function and Regulation

(2014) Sandeep Sheth et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adenosine receptors as drug targets — what are the challenges?

(2013) Jiang-Fan Chen et al.   NATURE REVIEWS DRUG DISCOVERY

Increasing small molecule drug developability in sub-optimal chemical space

(2013) Timothy J. Ritchie et al.   MedChemComm

Design and Characterization of Optimized Adenosine A2A/A1 Receptor Antagonists for the Treatment of Parkinson's Disease

(2012) Brian C. Shook et al.   JOURNAL OF MEDICINAL CHEMISTRY

Benzothiazinones: A Novel Class of Adenosine Receptor Antagonists Structurally Unrelated to Xanthine and Adenine Derivatives

(2012) Michael Gütschow et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bioavailability and antioxidant potential of rooibos flavonoids in humans following the consumption of different rooibos formulations

(2011) Till Breiter et al.   FOOD CHEMISTRY

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

(2011) B. B. Fredholm et al.   PHARMACOLOGICAL REVIEWS

Black tea improves attention and self-reported alertness

(2010) E.A. De Bruin et al.   APPETITE

What is modulating solubility in simulated intestinal fluids?

(2010) Giorgio Ottaviani et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bioavailability ofC-Linked Dihydrochalcone and Flavanone Glucosides in Humans Following Ingestion of Unfermented and Fermented Rooibos Teas

(2009) Angélique Stalmach et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant Activity of the Dihydrochalcones Aspalathin and Nothofagin and Their Corresponding Flavones in Relation to Other Rooibos (Aspalathus linearis) Flavonoids, Epigallocatechin Gallate, and Trolox

(2009) Petra W. Snijman et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Characterization of Phenolic Compounds in Rooibos Tea

(2008) Nicole Krafczyk et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides—A review

(2008) E. Joubert et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases

(2007) Ruth Brenk et al.   ChemMedChem