Suppressors of cGAS‐STING are downregulated during fin‐limb regeneration and aging in aquatic vertebrates

PML and PML-like exonucleases restrict retrotransposons in jawed vertebrates

(2023) Sabateeshan Mathavarajah et al.   NUCLEIC ACIDS RESEARCH

STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage

(2023) Chenyao Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging

(2023) Carine Raquel Richter Schmitz et al.   Frontiers in Immunology

CRISPR/Cas9-Induced Knockout of Sting Increases Susceptibility of Zebrafish to Bacterial Infection

(2023) Sarithaa Sellaththurai et al.   Biomolecules

Evidence of requirement for homologous‐mediated DNA repair during Ambystoma mexicanum limb regeneration

(2022) Ulises Omar García‐Lepe et al.   DEVELOPMENTAL DYNAMICS

Aging Activates the Immune System and Alters the Regenerative Capacity in the Zebrafish Heart

(2022) Hanna Reuter et al.   Cells

Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution

(2022) Fang Ye et al.   Nature Communications

The Relationship between Reactive Oxygen Species and the cGAS/STING Signaling Pathway in the Inflammaging Process

(2022) Bárbara Andrade et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

(2022) Xu Wang et al.   NEURON

The crosstalk between DNA damage response components and DNA-sensing innate immune signaling pathways

(2021) Feng Lin et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Interferon b drives intestinal regeneration after radiation

(2021) Brian J. Leibowitz et al.   Science Advances

STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia

(2021) Giulio Morozzi et al.   iScience

Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration

(2020) Konstantinos Sousounis et al.   eLife

Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway

(2020) Zhi-fei Liu et al.   FASEB JOURNAL

Molecular mechanisms and cellular functions of cGAS–STING signalling

(2020) Karl-Peter Hopfner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis

(2020) Hanbo Li et al.   Protein & Cell

DNA repair during regeneration in Ambystoma mexicanum

(2020) Ulises Omar García‐Lepe et al.   DEVELOPMENTAL DYNAMICS

Blastemal progenitors modulate immune signaling during early limb regeneration

(2019) Stephanie L. Tsai et al.   DEVELOPMENT

L1 drives IFN in senescent cells and promotes age-associated inflammation

(2019) Marco De Cecco et al.   NATURE

An emerging role for calcium signalling in innate and autoimmunity via the cGAS-STING axis

(2019) Sabateeshan Mathavarajah et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-κB Signaling Adaptation

(2019) Carina C. de Oliveira Mann et al.   Cell Reports

DNA sensing by the cGAS–STING pathway in health and disease

(2019) Mona Motwani et al.   NATURE REVIEWS GENETICS

Deep evolutionary origin of limb and fin regeneration

(2019) Sylvain Darnet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of All Three Types in Cartilaginous Fishes Enables Phylogenetic Resolution of the Origins and Evolution of Interferons

(2019) Anthony K. Redmond et al.   Frontiers in Immunology

Towards comparative analyses of salamander limb regeneration

(2019) Varun B. Dwaraka et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

(2019) Hiroshi Maekawa et al.   Cell Reports

Evolution of IFN subgroups in bony fish - 1:Group I-III IFN exist in early ray-finned fish, with group II IFN subgroups present in the Holostean spotted gar, Lepisosteus oculatus

(2019) Fuguo Liu et al.   FISH & SHELLFISH IMMUNOLOGY

The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

(2018) Tuo Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Age-associated changes in electrical function of the zebrafish heart

(2018) Matthew R. Stoyek et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

cGAS and STING: At the intersection of DNA and RNA virus-sensing networks

(2018) Guoxin Ni et al.   PLoS Pathogens

Hyaluronic acid in the tail and limb of amphibians and lizards recreates permissive embryonic conditions for regeneration due to its hygroscopic and immunosuppressive properties

(2017) Lorenzo Alibardi   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

(2017) Selene Glück et al.   NATURE CELL BIOLOGY

cGAS is essential for cellular senescence

(2017) Hui Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration

(2016) Chi-Chung Wu et al.   DEVELOPMENTAL CELL

The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

(2016) Ingo Braasch et al.   NATURE GENETICS

Tetrapod limb and sarcopterygian fin regeneration share a core genetic programme

(2016) Acacio F. Nogueira et al.   Nature Communications

Conservation of the STING-Mediated Cytosolic DNA Sensing Pathway in Zebrafish

(2015) Rui Ge et al.   JOURNAL OF VIROLOGY

Mechanisms underlying vertebrate limb regeneration: lessons from the salamander

(2014) Jeremy P. Brockes et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

TREX1 Deficiency Triggers Cell-Autonomous Immunity in a cGAS-Dependent Manner

(2014) A. Ablasser et al.   JOURNAL OF IMMUNOLOGY

Macrophages are required for adult salamander limb regeneration

(2013) James W. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Limb regeneration

(2012) András Simon et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Zebrafish kidney stromal cell lines support multilineage hematopoiesis

(2009) D. L. Stachura et al.   BLOOD

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL