Targeting the SPHK1/S1P/S1PR2 axis ameliorates GH‐secreted pituitary adenoma progression

Elevated sphingosine-1-phosphate lyase leads to increased metabolism and reduced survival in adrenocortical carcinoma

(2023) Jack L Williams et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Approach to the Patient With Treatment-resistant Acromegaly

(2022) Eva C Coopmans et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma

(2022) Chenxing Ji et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Sphingosine 1-phosphate receptor-targeted therapeutics in rheumatic diseases

(2022) Nathalie Burg et al.   Nature Reviews Rheumatology

Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer

(2022) Prachi Gupta et al.   Advanced Science

circSSU72 Promotes Cell Proliferation, Migration and Invasion of Papillary Thyroid Carcinoma Cells by Targeting miR-451a/S1PR2 Axis

(2022) Zeyu Zhang et al.   Frontiers in Cell and Developmental Biology

Acromegaly: pathogenesis, diagnosis, and management

(2022) Maria Fleseriu et al.   Lancet Diabetes & Endocrinology

SphK-produced S1P in somatic cells is indispensable for LH-EGFR signaling-induced mouse oocyte maturation

(2022) Feifei Yuan et al.   Cell Death & Disease

Autophagy in normal pituitary and pituitary tumor cells and its potential role in the actions of somatostatin receptor ligands in acromegaly

(2021) Giovanni Tulipano et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Sphingosine 1-phosphate receptor modulators in multiple sclerosis and other conditions

(2021) Marisa P McGinley et al.   LANCET

Effect of sphingosine-1-phosphate on cryopreserved sheep testicular explants cultured in vitro

(2019) Ram Pratap Singh et al.   THERIOGENOLOGY

Sphk1/S1P/S1PR1 Signaling is Involved in the Development of Autoimmune Thyroiditis in Patients and NOD.H-2h4 Mice

(2019) Cheng Han et al.   THYROID

Sphingosine 1-phosphate: Lipid signaling in pathology and therapy

(2019) Andreane Cartier et al.   SCIENCE

Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis

(2018) Masayuki Nagahashi et al.   CANCER RESEARCH

S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma

(2018) Yifei Shen et al.   EBioMedicine

The value of an acute octreotide suppression test in predicting short-term efficacy of somatostatin analogues in acromegaly

(2016) Meng Wang et al.   ENDOCRINE JOURNAL

Systemic distribution, subcellular localization and differential expression of sphingosine-1-phosphate receptors in benign and malignant human tissues

(2014) Chunyi Wang et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Attenuated RORC Expression in the Presence of EMT Progression in Somatotroph Adenomas following Treatment with Somatostatin Analogs Is Associated with Poor Clinical Recovery

(2013) Tove Lekva et al.   PLoS One

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis

(2012) Suriyan Ponnusamy et al.   EMBO Molecular Medicine

A Consensus on Criteria for Cure of Acromegaly

(2010) A. Giustina et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Prognostic Significance of the Ki-67 Labeling Index in Growth Hormone-Secreting Pituitary Adenomas

(2008) A. Fusco et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM