The p300 Inhibitor A-485 Exerts Antitumor Activity in Growth Hormone Pituitary Adenoma

DNA damage and growth hormone hypersecretion in pituitary somatotroph adenomas

(2020) Anat Ben-Shlomo et al.   JOURNAL OF CLINICAL INVESTIGATION

Acromegaly

(2019) Annamaria Colao et al.   Nature Reviews Disease Primers

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome

(2018) Brian T. Weinert et al.   CELL

Cyclic 3′,5′-adenosine monophosphate (cAMP) signaling in the anterior pituitary gland in health and disease

(2018) Laura C. Hernández-Ramírez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A Consensus Statement on acromegaly therapeutic outcomes

(2018) Shlomo Melmed et al.   Nature Reviews Endocrinology

Diagnosis and Treatment of Pituitary Adenomas

(2017) Mark E. Molitch   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Increased β-catenin and c-myc expression predict aggressive growth of non-functioning pituitary adenomas: An assessment using a tissue microarray-based approach

(2017) Chunhui Liu et al.   Molecular Medicine Reports

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

(2017) Loren M. Lasko et al.   NATURE

Long-Term Endocrine Outcomes Following Endoscopic Endonasal Transsphenoidal Surgery for Acromegaly and Associated Prognostic Factors

(2017) Harish Babu et al.   NEUROSURGERY

Updates in outcomes of stereotactic radiation therapy in acromegaly

(2017) Monica Livia Gheorghiu   Pituitary

Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay

(2017) Zhifeng Chen et al.   MedChemComm

Outcome of Endoscopic Transsphenoidal Surgery for Acromegaly

(2017) Jung Hee Kim et al.   World Neurosurgery

The value of an acute octreotide suppression test in predicting short-term efficacy of somatostatin analogues in acromegaly

(2016) Meng Wang et al.   ENDOCRINE JOURNAL

Acromegaly incidence, prevalence, complications and long-term prognosis: a nationwide cohort study

(2016) Jakob Dal et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Somatostatin and dopamine receptor regulation of pituitary somatotroph adenomas

(2016) Anat Ben-Shlomo et al.   Pituitary

RADIOTHERAPY VERSUS RADIOSURGERY IN TREATING PATIENTS WITH ACROMEGALY: A SYSTEMATIC REVIEW AND META-ANALYSIS

(2015) Abd Moain Abu Dabrh et al.   Endocrine Practice

Mortality in acromegaly: a 20-year follow-up study

(2015) Elina Ritvonen et al.   ENDOCRINE-RELATED CANCER

The epidemiology of pituitary adenomas in Iceland, 1955–2012: a nationwide population-based study

(2015) Tomas Thor Agustsson et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Specific inhibition of mTOR pathway induces anti-proliferative effect and decreases the hormone secretion in cultured pituitary adenoma cells

(2015) Rong Xie et al.   JOURNAL OF NEURO-ONCOLOGY

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia

(2015) G Giotopoulos et al.   ONCOGENE

The incidence and prevalence of acromegaly, a nationwide study from 1955 through 2013

(2015) Gudrun Thuridur Hoskuldsdottir et al.   Pituitary

Interpreting biochemical control response rates with first-generation somatostatin analogues in acromegaly

(2015) Annamaria Colao et al.   Pituitary

Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression

(2015) H. Ogiwara et al.   Cancer Discovery

Escape and lipodystrophy in acromegaly during pegvisomant therapy, a retrospective multicentre Spanish study

(2014) Gemma Sesmilo et al.   CLINICAL ENDOCRINOLOGY

The PI3K/AKT/mTOR pathway in the pathophysiology and treatment of pituitary adenomas

(2014) Eric Monsalves et al.   ENDOCRINE-RELATED CANCER

Long-Term Efficacy and Safety of Pegvisomant in Combination With Long-Acting Somatostatin Analogs in Acromegaly

(2014) S. J. C. M. M. Neggers et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Acromegaly: An Endocrine Society Clinical Practice Guideline

(2014) Laurence Katznelson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Correlations of Pituitary Tumor Transforming Gene Expression with Human Pituitary Adenomas: A Meta-Analysis

(2014) Jian-Qi Xiao et al.   PLoS One

mTOR is Frequently Active in GH-Secreting Pituitary Adenomas without Influencing their Morphopathological Features

(2013) Emir Ahmed Sajjad et al.   ENDOCRINE PATHOLOGY

Inhibition of PI3K/AKT/mTOR Pathway Enhances Temozolomide-Induced Cytotoxicity in Pituitary Adenoma Cell Lines in Vitro and Xenografted Pituitary Adenoma in Female Nude Mice

(2013) Congxin Dai et al.   ENDOCRINOLOGY

Endoscopic vs Microsurgical Transsphenoidal Surgery for Acromegaly: Outcomes in a Concurrent Series of Patients Using Modern Criteria For Remission

(2013) Robert M. Starke et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Predictors of morbidity and mortality in acromegaly: an Italian survey

(2012) M Arosio et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

High expression of p300 is linked to aggressive features and poor prognosis of Nasopharyngeal Carcinoma

(2012) Zhi-Wei Liao et al.   Journal of Translational Medicine

Histone Acetylation Patterns of Typical and Atypical Pituitary Adenomas Indicate Epigenetic Shift of these Tumours

(2011) A. Ebrahimi et al.   JOURNAL OF NEUROENDOCRINOLOGY

High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma

(2011) Mei Li et al.   Journal of Translational Medicine

Mortality in Patients with Pituitary Disease

(2010) Mark Sherlock et al.   ENDOCRINE REVIEWS

Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases

(2010) David C. Bedford et al.   Epigenetics

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney

(2009) R. Ariel Gomez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro

(2009) Alexander Gorshtein et al.   ENDOCRINE-RELATED CANCER

Histone acetyltransferase p300 regulates the expression of human pituitary tumor transforming gene (hPTTG)

(2009) Tian Li et al.   Journal of Genetics and Genomics

Rapid and sustained reduction of serum growth hormone and insulin-like growth factor-1 in patients with acromegaly receiving lanreotide Autogel® therapy: a randomized, placebo-controlled, multicenter study with a 52 week open extension

(2009) Shlomo Melmed et al.   Pituitary