Recombinant production of hormonally active human insulin from pre-proinsulin by Tetrahymena thermophila

Absolute quantification of chromosome copy numbers in the polyploid macronucleus of Tetrahymena thermophila at the single‐cell level

(2022) Yuanyuan Zhou et al.   JOURNAL OF EUKARYOTIC MICROBIOLOGY

The in vivo Tetrahymena thermophila extracellular glucose drop assay for characterization of mammalian insulin activity

(2021) Ayça Fulya Üstüntanir Dede et al.   EUROPEAN JOURNAL OF PROTISTOLOGY

Characterization and use of Tetrahymena thermophila artificial chromosome 2 (TtAC2) constructed by biomimetic of macronuclear rDNA minichromosome

(2021) Mehmet Çalıseki et al.   MICROBIOLOGICAL RESEARCH

Construction and dynamic characterization of a Tetrahymena thermophila macronuclear artificial chromosome

(2020) Ayça Fulya Üstüntanır Dede et al.   GENE

Expression and purification of recombinant human insulin from E. coli 20 strain

(2019) Marcin Zieliński et al.   PROTEIN EXPRESSION AND PURIFICATION

What Gives an Insulin Hexamer Its Unique Shape and Stability? Role of Ten Confined Water Molecules

(2018) Saumyak Mukherjee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

(2018) Mohsen Akbarian et al.   PLoS One

Ion channels as therapeutic antibody targets

(2018) Catherine J. Hutchings et al.   mAbs

Dissecting carboxypeptidase E: properties, functions and pathophysiological roles in disease

(2017) Lin Ji et al.   Endocrine Connections

Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity

(2016) Jenny Calow et al.   mAbs

Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

(2016) Eileen P Hamilton et al.   eLife

Identification of neutral and acidic deoxyribonuclease activities in Tetrahymena thermophila life stages

(2015) Erhan Aslan et al.   EUROPEAN JOURNAL OF PROTISTOLOGY

A novel mitochondrial nuclease-associated protein: A major executor of the programmed nuclear death inTetrahymena thermophila

(2014) Eriko Osada et al.   BIOLOGY OF THE CELL

Cell factories for insulin production

(2014) Nabih A Baeshen et al.   Microbial Cell Factories

A Novel Malaria Vaccine Candidate Antigen Expressed in Tetrahymena thermophila

(2014) Graeme J. M. Cowan et al.   PLoS One

Purification and functional characterization of pancreatic insulin from camel (Camelus dromedarius)

(2014) Babiker A. Elamin et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

Transcriptome Analysis of the Model Protozoan, Tetrahymena thermophila, Using Deep RNA Sequencing

(2012) Jie Xiong et al.   PLoS One

A Novel Robust Heat-inducible Promoter for Heterologous Gene Expression in Tetrahymena thermophila

(2012) Ting Yu et al.   PROTIST

Expression, secretion and surface display of a human alkaline phosphatase by the ciliate Tetrahymena thermophila

(2011) Ingo Aldag et al.   BMC BIOTECHNOLOGY

A Knockout Mutation of a Constitutive GPCR in Tetrahymena Decreases Both G-Protein Activity and Chemoattraction

(2011) Thomas J. Lampert et al.   PLoS One

Constitutive Secretion in Tetrahymena thermophila

(2010) Catherine L. Madinger et al.   EUKARYOTIC CELL

Application of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin

(2010) Chandrasekhar Gurramkonda et al.   Microbial Cell Factories

Microarray Analyses of Gene Expression during the Tetrahymena thermophila Life Cycle

(2009) Wei Miao et al.   PLoS One

Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure

(2008) Robert S Coyne et al.   BMC GENOMICS

High efficiency transformation of Tetrahymena using a codon-optimized neomycin resistance gene

(2008) Kazufumi Mochizuki   GENE

Patterns of Codon Usage in two Ciliates that Reassign the Genetic Code: Tetrahymena thermophila and Paramecium tetraurelia

(2008) Hannah M.W. Salim et al.   PROTIST