Multi‐omic network analysis identified betacellulin as a novel target of omega‐3 fatty acid attenuation of western diet‐induced nonalcoholic steatohepatitis
出版年份 2023 全文链接
标题
Multi‐omic network analysis identified betacellulin as a novel target of omega‐3 fatty acid attenuation of western diet‐induced nonalcoholic steatohepatitis
作者
关键词
-
出版物
EMBO Molecular Medicine
Volume -, Issue -, Pages -
出版商
EMBO
发表日期
2023-10-20
DOI
10.15252/emmm.202318367
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
- (2023) Seddik Hammad et al. Cell Death & Disease
- Integrins as a drug target in liver fibrosis
- (2022) Syedia R. Rahman et al. LIVER INTERNATIONAL
- Gut Microbiome and Organ Fibrosis
- (2022) Carolina F. F. A. Costa et al. Nutrients
- Trends in Antidiabetic Drug Discovery: FDA Approved Drugs, New Drugs in Clinical Trials and Global Sales
- (2022) Amelia D. Dahlén et al. Frontiers in Pharmacology
- Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease
- (2022) Michael Fridén et al. Frontiers in Medicine
- A new preclinical model of western diet‐induced progression of non‐alcoholic steatohepatitis to hepatocellular carcinoma
- (2022) Christopher D. Green et al. FASEB JOURNAL
- Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12+ macrophages
- (2022) Zhipeng Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Systematic review and meta-analysis: analysis of variables influencing the interpretation of clinical trial results in NAFLD
- (2022) Javier Ampuero et al. JOURNAL OF GASTROENTEROLOGY
- Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
- (2022) Suresh Chava et al. iScience
- Current therapies and new developments in NASH
- (2022) Jean-François Dufour et al. GUT
- Tirzepatide Once Weekly for the Treatment of Obesity
- (2022) Ania M. Jastreboff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease
- (2022) Naoto Fujiwara et al. Science Translational Medicine
- Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes
- (2021) Richard R. Rodrigues et al. Nature Communications
- Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice
- (2021) Heather M. Kahalehili et al. Frontiers in Immunology
- NASH limits anti-tumour surveillance in immunotherapy-treated HCC
- (2021) Dominik Pfister et al. NATURE
- FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells
- (2021) Toshikatsu Tsuji et al. ONCOGENE
- LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through the MEK/ERK signaling pathway
- (2021) Ziye Chen et al. Molecular Metabolism
- Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects
- (2021) Emeline Dierge et al. Cell Metabolism
- TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
- (2021) Tianhe Sun et al. Science Translational Medicine
- Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
- (2021) Khiem C. Lam et al. CELL
- Advancing the global public health agenda for NAFLD: a consensus statement
- (2021) Jeffrey V. Lazarus et al. Nature Reviews Gastroenterology & Hepatology
- Ensembl 2022
- (2021) Fiona Cunningham et al. NUCLEIC ACIDS RESEARCH
- Therapeutic landscape for NAFLD in 2020
- (2020) Brent A. Neuschwander-Tetri GASTROENTEROLOGY
- Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis
- (2020) Jason S. Seidman et al. IMMUNITY
- Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NF-κB pathways
- (2020) Litao Wu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice
- (2020) Kathrin Hedegger et al. Molecular Oncology
- Gut-resident CX3CR1hi macrophages induce tertiary lymphoid structures and IgA response in situ
- (2020) Balázs Koscsó et al. Science Immunology
- Reciprocal Interplay Between Fibrillar Collagens and Collagen-Binding Integrins: Implications in Cancer Progression and Metastasis
- (2020) Isabelle Bourgot et al. Frontiers in Oncology
- FANTOM enters 20th year: expansion of transcriptomic atlases and functional annotation of non-coding RNAs
- (2020) Imad Abugessaisa et al. NUCLEIC ACIDS RESEARCH
- From NASH to HCC: current concepts and future challenges
- (2019) Quentin M. Anstee et al. Nature Reviews Gastroenterology & Hepatology
- Oxidative Stress and Non-Alcoholic Fatty Liver Disease: Effects of Omega-3 Fatty Acid Supplementation
- (2019) Jinchunzi Yang et al. Nutrients
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice
- (2019) Manuel Garcia-Jaramillo et al. PLoS One
- Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
- (2019) Yingyao Zhou et al. Nature Communications
- Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis
- (2019) Xuelian Xiong et al. MOLECULAR CELL
- Assessment of network module identification across complex diseases
- (2019) Sarvenaz Choobdar et al. NATURE METHODS
- Non-alcoholic fatty liver disease in adults: Current concepts in etiology, outcomes and management
- (2019) Thomas Marjot et al. ENDOCRINE REVIEWS
- Effects of Omega-3 Fatty Acids on Immune Cells
- (2019) Saray Gutiérrez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Resolving the fibrotic niche of human liver cirrhosis at single-cell level
- (2019) P. Ramachandran et al. NATURE
- Nonalcoholic Steatohepatitis (NASH) and Hepatic Fibrosis: Emerging Therapies
- (2018) Julia Wattacheril et al. Annual Review of Pharmacology and Toxicology
- Marine ω-3 Polyunsaturated Fatty Acid and Fish Intake after Colon Cancer Diagnosis and Survival: CALGB 89803 (Alliance)
- (2018) Erin L. Van Blarigan et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases
- (2018) Varman T. Samuel et al. Cell Metabolism
- Mitochondria in non-alcoholic fatty liver disease
- (2018) Inês C.M. Simões et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Pharmacotherapy for NASH: Current and emerging
- (2018) Monica A. Konerman et al. JOURNAL OF HEPATOLOGY
- Systematic review and meta-analysis of controlled intervention studies on the effectiveness of long-chain omega-3 fatty acids in patients with nonalcoholic fatty liver disease
- (2018) Kathy Musa-Veloso et al. NUTRITION REVIEWS
- Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease
- (2018) Donald B. Jump et al. PHARMACOLOGY & THERAPEUTICS
- Critical role of FOXO3a in carcinogenesis
- (2018) Ying Liu et al. Molecular Cancer
- Evaluation of a High Concentrate Omega-3 for Correcting the Omega-3 Fatty Acid Nutritional Deficiency in Non-Alcoholic Fatty Liver Disease (CONDIN)
- (2018) Derek Tobin et al. Nutrients
- Persistence to Treatment with Novel Antidiabetic Drugs (Dipeptidyl Peptidase-4 Inhibitors, Sodium-Glucose Co-Transporter-2 Inhibitors, and Glucagon-Like Peptide-1 Receptor Agonists) in People with Type 2 Diabetes: A Nationwide Cohort Study
- (2018) György Jermendy et al. Diabetes Therapy
- Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children
- (2018) Melinda H. Spooner et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia
- (2018) Deepak L. Bhatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study
- (2017) L Hodson et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota
- (2017) Henry Watson et al. GUT
- SCENIC: single-cell regulatory network inference and clustering
- (2017) Sara Aibar et al. NATURE METHODS
- Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice
- (2017) Kelli A. Lytle et al. PLoS One
- Omega-3 PUFA modulate lipogenesis, ER stress, and mitochondrial dysfunction markers in NASH – Proteomic and lipidomic insight
- (2017) Lívia Samara dos Reis Rodrigues Okada et al. CLINICAL NUTRITION
- Unexpected links reflect the noise in networks
- (2016) Anatoly Yambartsev et al. Biology Direct
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- A crowdsourcing approach for reusing and meta-analyzing gene expression data
- (2016) Naisha Shah et al. NATURE BIOTECHNOLOGY
- Expression and Function of the Epidermal Growth Factor Receptor in Physiology and Disease
- (2016) Jianchun Chen et al. PHYSIOLOGICAL REVIEWS
- TGF-β1 and TGF-β2 abundance in liver diseases of mice and men
- (2016) Anne Dropmann et al. Oncotarget
- Making Sense of Transcription Networks
- (2015) Trevor R. Sorrells et al. CELL
- Uncovering effects of antibiotics on the host and microbiota using transkingdom gene networks
- (2015) Andrey Morgun et al. GUT
- Nonalcoholic Fatty Liver Disease
- (2015) Mary E. Rinella JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis inLdlr−/−mice by targeting the TGFβ-Smad3 pathway
- (2015) Kelli A. Lytle et al. JOURNAL OF LIPID RESEARCH
- Potential for Dietary ω-3 Fatty Acids to Prevent Nonalcoholic Fatty Liver Disease and Reduce the Risk of Primary Liver Cancer
- (2015) Donald B Jump et al. Advances in Nutrition
- Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells
- (2014) Lin Shi et al. Journal of Translational Medicine
- EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation
- (2014) Hanane Lanaya et al. NATURE CELL BIOLOGY
- The ABC of BTC: Structural properties and biological roles of betacellulin
- (2014) Maik Dahlhoff et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Integrins and cadherins as therapeutic targets in fibrosis
- (2014) Sandeep K. Agarwal Frontiers in Pharmacology
- DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery
- (2013) Markus Ahrens et al. Cell Metabolism
- Docosahexaenoic Acid Attenuates Hepatic Inflammation, Oxidative Stress, and Fibrosis without Decreasing Hepatosteatosis in a Ldlr−/− Mouse Model of Western Diet-Induced Nonalcoholic Steatohepatitis
- (2013) Christopher M. Depner et al. JOURNAL OF NUTRITION
- Preoperative 4-Week Supplementation with Omega-3 Polyunsaturated Fatty Acids Reduces Liver Volume and Facilitates Bariatric Surgery in Morbidly Obese Patients
- (2013) Antonio Iannelli et al. OBESITY SURGERY
- A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice
- (2013) Christopher M. Depner et al. PLoS One
- Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice
- (2012) Kouichi Miura et al. HEPATOLOGY
- InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation
- (2012) Karin Breuer et al. NUCLEIC ACIDS RESEARCH
- Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling
- (2011) D. A. Hume et al. BLOOD
- Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut
- (2011) Natalia Shulzhenko et al. NATURE MEDICINE
- Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice
- (2009) Astrid Spruss et al. HEPATOLOGY
- The epidermal growth factor receptor family: Biology driving targeted therapeutics
- (2008) M. J. Wieduwilt et al. CELLULAR AND MOLECULAR LIFE SCIENCES
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started