Potential for Dietary ω-3 Fatty Acids to Prevent Nonalcoholic Fatty Liver Disease and Reduce the Risk of Primary Liver Cancer

Hepatic stellate cells: central modulators of hepatic carcinogenesis

(2015) Alexandra I Thompson et al.   BMC GASTROENTEROLOGY

Effects of n-3 fish oil on metabolic and histological parameters in NASH: A double-blind, randomized, placebo-controlled trial

(2015) Curtis K. Argo et al.   JOURNAL OF HEPATOLOGY

MetaboAnalyst 3.0—making metabolomics more meaningful

(2015) Jianguo Xia et al.   NUCLEIC ACIDS RESEARCH

Hepatocellular carcinoma epidemiology

(2014) Cristina Bosetti et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

No Significant Effects of Ethyl-Eicosapentanoic Acid on Histologic Features of Nonalcoholic Steatohepatitis in a Phase 2 Trial

(2014) Arun J. Sanyal et al.   GASTROENTEROLOGY

Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: Results from the WELCOME* study

(2014) Eleonora Scorletti et al.   HEPATOLOGY

Gut microbiota and liver disease

(2014) Amit Goel et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

(2014) Robert N. Schuck et al.   PLoS One

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

(2014) S. A. Joyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental models of non-alcoholic fatty liver disease in rats

(2014) Otto Kucera   WORLD JOURNAL OF GASTROENTEROLOGY

Fatty Acid–Regulated Transcription Factors in the Liver

(2013) Donald B. Jump et al.   Annual Review of Nutrition

Omega-3 Fatty Acid Blood Levels

(2013) H. Robert Superko et al.   CIRCULATION

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

(2013) Takuji Ishimoto et al.   HEPATOLOGY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Docosahexaenoic Acid Attenuates Hepatic Inflammation, Oxidative Stress, and Fibrosis without Decreasing Hepatosteatosis in a Ldlr−/− Mouse Model of Western Diet-Induced Nonalcoholic Steatohepatitis

(2013) Christopher M. Depner et al.   JOURNAL OF NUTRITION

Fructose-induced stress signaling in the liver involves methylglyoxal

(2013) Yuren Wei et al.   Nutrition & Metabolism

A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

(2013) Christopher M. Depner et al.   PLoS One

SATgenɛ dietary model to implement diets of differing fat composition in prospectively genotyped groups (apoE) using commercially available foods

(2012) Stacey Lockyer et al.   BRITISH JOURNAL OF NUTRITION

Mechanisms of Simple Hepatic Steatosis

(2012) Scott C. Matherly et al.   Clinics in Liver Disease

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

Can Dietary Fish Intake Prevent Liver Cancer?

(2012) Neal D. Freedman et al.   GASTROENTEROLOGY

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

(2012) Naga Chalasani et al.   GASTROENTEROLOGY

Non-alcoholic steatohepatitis: The role of oxidized low-density lipoproteins

(2012) Sofie M.A. Walenbergh et al.   JOURNAL OF HEPATOLOGY

Menhaden Oil Decreases High-Fat Diet–Induced Markers of Hepatic Damage, Steatosis, Inflammation, and Fibrosis in Obese Ldlr−/− Mice

(2012) Christopher M. Depner et al.   JOURNAL OF NUTRITION

Mechanisms of Action of (n-3) Fatty Acids

(2012) Philip C. Calder   JOURNAL OF NUTRITION

The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease

(2012) Kyoko Nomura et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of dietary fatty acids in the pathology of metabolic syndrome

(2012) Ana Maria Lottenberg et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Low Docosahexaenoic Acid Content in Plasma Phospholipids is Associated with Increased Non-alcoholic Fatty Liver Disease in China

(2012) Ju-Sheng Zheng et al.   LIPIDS

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

(2012) Jorge Henao-Mejia et al.   NATURE

LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease

(2012) Veerle Bieghs et al.   PLoS One

Role of ceramides in nonalcoholic fatty liver disease

(2012) Mangesh Pagadala et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease

(2012) Matteo Nicola Dario Di Minno   WORLD JOURNAL OF GASTROENTEROLOGY

Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2012) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Intake of added sugars in the United States: what is the measure?

(2011) Bernadette P Marriott et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

(2011) Michael Charlton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial

(2011) V. Nobili et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Increased erythrocytes n-3 and n-6 polyunsaturated fatty acids is significantly associated with a lower prevalence of steatosis in patients with type 2 diabetes

(2011) J.M. Petit et al.   CLINICAL NUTRITION

Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase

(2011) David A. Brenner et al.   HEPATOLOGY RESEARCH

Histological features of non-alcoholic fatty liver disease: What is important?

(2011) Etsuko Hashimoto et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Omega-3 supplementation and non-alcoholic fatty liver disease: A systematic review and meta-analysis

(2011) Helen M. Parker et al.   JOURNAL OF HEPATOLOGY

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

(2011) Savitha Subramanian et al.   JOURNAL OF LIPID RESEARCH

Genetic determinants of hepatic steatosis in man

(2011) Amanda J. Hooper et al.   JOURNAL OF LIPID RESEARCH

Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets

(2011) Barbara D. Pachikian et al.   PLoS One

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Nutrition and physical activity in NAFLD: An overview of the epidemiological evidence

(2011) Shira Zelber-Sagi   WORLD JOURNAL OF GASTROENTEROLOGY

Current status of novel antifibrotic therapies in patients with chronic liver disease

(2011) Michal Cohen-Naftaly et al.   Therapeutic Advances in Gastroenterology

Preventive Effects of Eicosapentaenoic Acid on Coronary Artery Disease in Patients With Peripheral Artery Disease

(2010) Yuichi Ishikawa et al.   CIRCULATION JOURNAL

Low concentrations of serum n-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease patients with liver injury

(2010) Tomonori Kishino et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

The therapeutic potential of long-chain omega-3 fatty acids in nonalcoholic fatty liver disease

(2010) Haim Shapiro et al.   CLINICAL NUTRITION

Intake of Added Sugars and Selected Nutrients in the United States, National Health and Nutrition Examination Survey (NHANES) 2003—2006

(2010) Bernadette P. Marriott et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Epidemiology of Non-Alcoholic Fatty Liver Disease

(2010) Stefano Bellentani et al.   DIGESTIVE DISEASES

Treatment with Ω-3 fatty acids but not exendin-4 improves hepatic steatosis

(2010) Deepti G. Bulchandani et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice

(2010) Kristiaan Wouters et al.   FEBS LETTERS

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

(2010) Manal F. Abdelmalek et al.   HEPATOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Effects of a 1-year dietary intervention with n-3 polyunsaturated fatty acid-enriched olive oil on non-alcoholic fatty liver disease patients: a preliminary study

(2010) Francesco Sofi et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Epidemiology of the metabolic syndrome in the USA

(2010) Arthur J McCULLOUGH   Journal of Digestive Diseases

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Emulsified lipids increase endotoxemia: possible role in early postprandial low-grade inflammation

(2010) Fabienne Laugerette et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

(2010) Jung Sub Lim et al.   Nature Reviews Gastroenterology & Hepatology

The Etiology of Hepatocellular Carcinoma and Consequences for Treatment

(2010) A. J. Sanyal et al.   ONCOLOGIST

Changes in Intakes of Total and Added Sugar and their Contribution to Energy Intake in the U.S.

(2010) Ock K. Chun et al.   Nutrients

Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome

(2009) C. H. KIM et al.   CLEVELAND CLINIC JOURNAL OF MEDICINE

Decreased survival of subjects with elevated liver function tests during a 28-year follow-up

(2009) Cecilia Söderberg et al.   HEPATOLOGY

Dietary Fish Oil Exerts Hypolipidemic Effects in Lean and Insulin Sensitizing Effects in Obese LDLR−/− Mice

(2009) Viswanathan Saraswathi et al.   JOURNAL OF NUTRITION

Effectiveness of Combined Statin Plus Omega-3 Fatty Acid Therapy for Mixed Dyslipidemia

(2008) Philip Barter et al.   AMERICAN JOURNAL OF CARDIOLOGY

Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent

(2008) Laura H. Tetri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Fructose-induced structural and functional modifications of hemoglobin: Implication for oxidative stress in diabetes mellitus

(2008) Tania Bose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Competitive inhibition of leptin signaling results in amelioration of liver fibrosis through modulation of stellate cell function

(2008) Eran Elinav et al.   HEPATOLOGY

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

(2008) Kristiaan Wouters et al.   HEPATOLOGY

Nutritional investigation of non-obese patients with non-alcoholic fatty liver disease: The significance of dietary cholesterol

(2008) Kenichiro Yasutake et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

(2008) Fabio Marra et al.   TRENDS IN MOLECULAR MEDICINE