Open-Source System for Real-Time Functional Assessment of In Vitro Filtration Barriers

Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype

(2023) Daan C. ‘t Hart et al.   Biosensors-Basel

Detailed numerical evaluation of diffusion convection equation in layered reservoirs during tracer injection

(2023) Mahmood Moayyedi et al.   Scientific Reports

Human organs-on-chips for disease modelling, drug development and personalized medicine

(2022) Donald E. Ingber   NATURE REVIEWS GENETICS

A multi-organ chip with matured tissue niches linked by vascular flow

(2022) Kacey Ronaldson-Bouchard et al.   Nature Biomedical Engineering

Mass diffusion in multi-layer systems: an electrical analogue modelling approach

(2022) Pawel Rochowski et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Kidney-on-a-Chip: Mechanical Stimulation and Sensor Integration

(2022) Dan Wang et al.   SENSORS

3D proximal tubule-on-chip model derived from kidney organoids with improved drug uptake

(2022) Jeffrey O. Aceves et al.   Scientific Reports

Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery

(2022) Ken Hiratsuka et al.   Science Advances

Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies

(2021) Marianne K. Vormann et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Microfluidic integration of regeneratable electrochemical affinity-based biosensors for continual monitoring of organ-on-a-chip devices

(2021) Julio Aleman et al.   Nature Protocols

A Biomimetic In Vitro Model of the Kidney Filtration Barrier Using Tissue‐Derived Glomerular Basement Membrane

(2021) Dan Wang et al.   Advanced Healthcare Materials

A Personalized Glomerulus Chip Engineered from Stem Cell-Derived Epithelium and Vascular Endothelium

(2021) Yasmin Roye et al.   Micromachines

Modeling the Glomerular Filtration Barrier and Intercellular Crosstalk

(2021) Kerstin Ebefors et al.   Frontiers in Physiology

Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion

(2021) Chrystian Junqueira Alves et al.   Nature Communications

Modeling ischemic stroke in a triculture neurovascular unit on-a-chip

(2021) Nienke R. Wevers et al.   Fluids and Barriers of the CNS

Efficient Drug Screening and Nephrotoxicity Assessment on Co-culture Microfluidic Kidney Chip

(2020) Lei Yin et al.   Scientific Reports

Rapid prototyping of multilayer microphysiological systems

(2020) Sanjin Hosic et al.   ACS Biomaterials-Science & Engineering

Molecular and functional characterization of urine‐derived podocytes from patients with Alport syndrome

(2020) Corinne Iampietro et al.   JOURNAL OF PATHOLOGY

Flow-enhanced vascularization and maturation of kidney organoids in vitro

(2019) Kimberly A. Homan et al.   NATURE METHODS

Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity

(2019) Rhodora C. Calizo et al.   Nature Communications

A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

(2019) Astgik Petrosyan et al.   Nature Communications

A Method for Determination and Simulation of Permeability and Diffusion in a 3D Tissue Model in a Membrane Insert System for Multi-well Plates

(2018) Hao-Hsiang Hsu et al.   Jove-Journal of Visualized Experiments

Glass-based organ-on-a-chip device for restricting small molecular absorption

(2018) Hirotada Hirama et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Chronic Kidney Disease

(2017) Angela C Webster et al.   LANCET

Multisensor-integrated organs-on-chips platform for automated and continual in situ monitoring of organoid behaviors

(2017) Yu Shrike Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

(2017) Samira Musah et al.   Nature Biomedical Engineering

Development of a Functional Glomerulus at the Organ Level on a Chip to Mimic Hypertensive Nephropathy

(2016) Mengying Zhou et al.   Scientific Reports

Using Proteinuria and Estimated Glomerular Filtration Rate to Classify Risk in Patients With Chronic Kidney Disease

(2013) Marcello Tonelli   ANNALS OF INTERNAL MEDICINE

Evaluation and Management of Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2012 Clinical Practice Guideline

(2013) Paul E. Stevens   ANNALS OF INTERNAL MEDICINE

Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

(2012) Hyun Jung Kim et al.   LAB ON A CHIP

Use of a porous membrane for gas bubble removal in microfluidic channels: physical mechanisms and design criteria

(2010) Jie Xu et al.   Microfluidics and Nanofluidics

Effect of membrane type and material on performance of a submerged membrane bioreactor

(2008) Jae-Hoon Choi et al.   CHEMOSPHERE