Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway
出版年份 2016 全文链接
标题
Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway
作者
关键词
-
出版物
LEUKEMIA
Volume 31, Issue 6, Pages 1314-1324
出版商
Springer Nature
发表日期
2016-11-22
DOI
10.1038/leu.2016.339
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genetic and epigenetic heterogeneity in acute myeloid leukemia
- (2016) Sheng Li et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- c-Jun NH 2 -terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study
- (2016) Mostafa Hussein et al. FERTILITY AND STERILITY
- Kruppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling
- (2016) K. Filarsky et al. HAEMATOLOGICA
- Kruppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling
- (2016) K. Filarsky et al. HAEMATOLOGICA
- Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes
- (2015) Wei Li et al. Molecular Cancer
- DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia
- (2015) Jessica Nordlund et al. Clinical Epigenetics
- miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias
- (2014) Deepti Malik et al. Molecular Cancer
- Promoter Hypermethylation of KLF4 Inactivates Its Tumor Suppressor Function in Cervical Carcinogenesis
- (2014) Wen-Ting Yang et al. PLoS One
- Krüppel Like Factor 4 Promoter Undergoes Active Demethylation during Monocyte/Macrophage Differentiation
- (2014) Manjula Karpurapu et al. PLoS One
- The Synergistic Repressive Effect of NF-κB and JNK Inhibitor on the Clonogenic Capacity of Jurkat Leukemia Cells
- (2014) Xinli Liu et al. PLoS One
- Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia
- (2013) P. Van Vlierberghe et al. BLOOD
- The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
- (2013) Bryan King et al. CELL
- Kruppel-like factor 4 blocks tumor cell proliferation and promotes drug resistance in multiple myeloma
- (2013) M. Schoenhals et al. HAEMATOLOGICA
- Expression of KLF4 is a predictive marker for survival in pediatric Burkitt lymphoma
- (2013) Alberto Valencia-Hipόlito et al. LEUKEMIA & LYMPHOMA
- Promoter DNA Methylation Pattern Identifies Prognostic Subgroups in Childhood T-Cell Acute Lymphoblastic Leukemia
- (2013) Magnus Borssén et al. PLoS One
- The roles of ATF2 (activating transcription factor 2) in tumorigenesis
- (2012) Malgorzata Gozdecka et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Discovery of Potent and Selective Covalent Inhibitors of JNK
- (2012) Tinghu Zhang et al. CHEMISTRY & BIOLOGY
- KLF4 translation level is associated with differentiation stage of different pediatric leukemias in both cell lines and primary samples
- (2012) Xiaoping Guo et al. CLINICAL AND EXPERIMENTAL MEDICINE
- The molecular basis of T cell acute lymphoblastic leukemia
- (2012) Pieter Van Vlierberghe et al. JOURNAL OF CLINICAL INVESTIGATION
- CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling
- (2012) Katrin Faber et al. JOURNAL OF CLINICAL INVESTIGATION
- Krüppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen
- (2012) Chun Shik Park et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Cytosolic Protein G0S2 Maintains Quiescence in Hematopoietic Stem Cells
- (2012) Takeshi Yamada et al. PLoS One
- Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia
- (2011) Irene Homminga et al. CANCER CELL
- The bottleneck of JNK signaling: Molecular and functional characteristics of MKK4 and MKK7
- (2011) Wiebke Haeusgen et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Biology, Risk Stratification, and Therapy of Pediatric Acute Leukemias: An Update
- (2011) Ching-Hon Pui et al. JOURNAL OF CLINICAL ONCOLOGY
- Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
- (2011) F Yu et al. ONCOGENE
- DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing
- (2011) Fabienne Brenet et al. PLoS One
- KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma
- (2010) H. Guan et al. BLOOD
- Kruppel-like Factor 4 (Klf4) Prevents Embryonic Stem (ES) Cell Differentiation by Regulating Nanog Gene Expression
- (2010) Peilin Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cutting Edge: Expression of the Transcription Factor E74-Like Factor 4 Is Regulated by the Mammalian Target of Rapamycin Pathway in CD8+ T Cells
- (2010) T. Yamada et al. JOURNAL OF IMMUNOLOGY
- Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia
- (2009) H. Kang et al. BLOOD
- Outcome of Patients Treated for Relapsed or Refractory Acute Lymphoblastic Leukemia: A Therapeutic Advances in Childhood Leukemia Consortium Study
- (2009) Richard H. Ko et al. JOURNAL OF CLINICAL ONCOLOGY
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Basal c-Jun NH2-terminal protein kinase activity is essential for survival and proliferation of T-cell acute lymphoblastic leukemia cells
- (2009) J. Cui et al. MOLECULAR CANCER THERAPEUTICS
- Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2
- (2009) Takeshi Yamada et al. NATURE IMMUNOLOGY
- Notch Signaling in Leukemia
- (2008) Jon C. Aster et al. Annual Review of Pathology-Mechanisms of Disease
- Kruppel-like Factor 4 Induces p27Kip1 Expression in and Suppresses the Growth and Metastasis of Human Pancreatic Cancer Cells
- (2008) D. Wei et al. CANCER RESEARCH
- Dynamic regulation ofc-Myc proto-oncogene expression during lymphocyte development revealed by aGFP-c-Myc knock-in mouse
- (2008) Ching-Yu Huang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia
- (2008) Mark Y. Chiang et al. JOURNAL OF CLINICAL INVESTIGATION
- Acute lymphoblastic leukaemia
- (2008) Ching-Hon Pui et al. LANCET
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now