标题
Overview of Amino Acid Modifications by Iron- and α-Ketoglutarate-Dependent Enzymes
作者
关键词
-
出版物
ACS Catalysis
Volume 13, Issue 7, Pages 4853-4865
出版商
American Chemical Society (ACS)
发表日期
2023-03-27
DOI
10.1021/acscatal.3c00424
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Comprehensive Structure–Activity Relationship Studies of Cepafungin Enabled by Biocatalytic C–H Oxidations
- (2023) Alexander Amatuni et al. ACS Central Science
- Directed Evolution of an Iron(II)‐ and α‐Ketoglutarate‐Dependent Dioxygenase for Site‐Selective Azidation of Unactivated Aliphatic C−H Bonds**
- (2023) Christian A. Gomez et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Discovery of a Cryptic Nitro Intermediate in the Biosynthesis of the 3-(trans-2′-Aminocyclopropyl)alanine Moiety of Belactosin A
- (2022) Alicia Engelbrecht et al. ORGANIC LETTERS
- Discovery of New Fe(II)/α-Ketoglutarate-Dependent Dioxygenases for Oxidation of l-Proline
- (2022) Erika Tassano et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Biosynthesis of Guanitoxin Enables Global Environmental Detection in Freshwater Cyanobacteria
- (2022) Stella T. Lima et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthesis of Glidomides and Elucidation of Different Mechanisms for Formation of β‐OH Amino Acid Building Blocks
- (2022) Hanna Chen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Molecular Insights into the Regioselectivity of the Fe(II)/2-Ketoglutarate-Dependent Dioxygenase-Catalyzed C–H Hydroxylation of Amino Acids
- (2022) Lunjie Wu et al. ACS Catalysis
- Stereoselectivity and Substrate Specificity of the Fe(II)/α-Ketoglutarate-Dependent Oxygenase TqaL
- (2022) Hui Tao et al. Journal of the American Chemical Society
- Modular Chemoenzymatic Synthesis of GE81112 B1 and Related Analogues Enables Elucidation of Its Key Pharmacophores
- (2021) Christian R. Zwick et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin
- (2021) Daniel A. Wirtz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Aziridine formation by a Fe(II)/α‐ketoglutarate dependent oxygenase and 2‐aminoisobutyrate biosynthesis in fungi
- (2021) Ikuro Abe et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Regiodivergent biocatalytic hydroxylation of l-Glutamine facilitated by characterization of Non-Heme dioxygenases from Non-Ribosomal peptide biosyntheses
- (2021) Hans Renata et al. TETRAHEDRON
- In vivo and in vitro reconstitution of unique key steps in cystobactamid antibiotic biosynthesis
- (2021) Sebastian Groß et al. Nature Communications
- Modulating Chemoselectivity in a Fe(II)/α-Ketoglutarate-Dependent Dioxygenase for the Oxidative Modification of a Nonproteinogenic Amino Acid
- (2021) Fabian Meyer et al. ACS Catalysis
- Enzymatic Synthesis of l - threo -β-Hydroxy-α-Amino Acids via Asymmetric Hydroxylation Using 2-Oxoglutarate-Dependent Hydroxylase from Sulfobacillus thermotolerans Y0017
- (2021) Ryotaro Hara et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Re‐Programming and Optimization of a L ‐Proline cis ‐4‐Hydroxylase for the cis ‐3‐Halogenation of its Native Substrate
- (2021) Athena Papadopoulou et al. ChemCatChem
- Identification of Cyclopropane Formation in the Biosyntheses of Hormaomycins and Belactosins: Sequential Nitration and Cyclopropanation by Metalloenzymes
- (2021) Xiaojun Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Stereodivergent Nitrocyclopropane Formation during Biosynthesis of Belactosins and Hormaomycins
- (2021) Shotaro Shimo et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reaction pathway engineering converts a radical hydroxylase into a halogenase
- (2021) Monica E. Neugebauer et al. Nature Chemical Biology
- Exploring the biocatalytic potential of Fe/α‐ketoglutarate dependent halogenases
- (2020) Moritz Voss et al. CHEMISTRY-A EUROPEAN JOURNAL
- Ibotenic Acid Biosynthesis in the Fly Agaric Is Initiated by Glutamate Hydroxylation
- (2020) Michael Müller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cofactor Generation Cascade for α-Ketoglutarate and Fe(II)-Dependent Dioxygenases
- (2020) Florian Busch et al. ACS Sustainable Chemistry & Engineering
- Halogenases: structures and functions
- (2020) Hannes Ludewig et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Industrial Application of 2-Oxoglutarate-Dependent Oxygenases
- (2019) Christin Peters et al. Catalysts
- Discovery of a pathway for terminal-alkyne amino acid biosynthesis
- (2019) J. A. Marchand et al. NATURE
- A family of radical halogenases for the engineering of amino-acid-based products
- (2019) Monica E. Neugebauer et al. Nature Chemical Biology
- Characterization of a Citrulline 4-Hydroxylase from Nonribosomal Peptide GE81112 Biosynthesis and Engineering of Its Substrate Specificity for the Chemoenzymatic Synthesis of Enduracididine
- (2019) Christian R. Zwick et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways
- (2019) Rémi Zallot et al. BIOCHEMISTRY
- Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles
- (2019) Tristan J. Smart et al. BIOORGANIC CHEMISTRY
- Site-Selective C–H Halogenation Using Flavin-Dependent Halogenases Identified via Family-Wide Activity Profiling
- (2019) Brian F. Fisher et al. ACS Central Science
- Biosynthetic Pathways to Nonproteinogenic α-Amino Acids
- (2019) Jason B. Hedges et al. CHEMICAL REVIEWS
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- (2018) Jon B. Patteson et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Remote C–H Hydroxylation by an α-Ketoglutarate-Dependent Dioxygenase Enables Efficient Chemoenzymatic Synthesis of Manzacidin C and Proline Analogs
- (2018) Christian R. Zwick et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids
- (2018) Li Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosyntheses
- (2018) Shu-Shan Gao et al. NATURAL PRODUCT REPORTS
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- (2018) Johanna Mattay et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
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- (2018) Christian R. Zwick et al. TETRAHEDRON
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- (2018) Amy Timmins et al. Catalysts
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- (2017) Peer Lukat et al. Chemical Science
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- (2016) Makoto Hibi et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Ferrous iron and α-ketoglutarate-dependent dioxygenases in the biosynthesis of microbial natural products
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- (2014) Makoto Hibi et al. ADVANCED SYNTHESIS & CATALYSIS
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- (2014) Makoto Hibi et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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- (2014) Damien Baud et al. ChemCatChem
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- (2014) Ryotaro Hara et al. JOURNAL OF BIOTECHNOLOGY
- Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase
- (2014) Megan L Matthews et al. Nature Chemical Biology
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- (2014) Kento Koketsu et al. ACS Synthetic Biology
- Recombinant protein expression in Escherichia coli: advances and challenges
- (2014) Germán L. Rosano et al. Frontiers in Microbiology
- Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds
- (2013) Christopher T. Walsh et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- EcdGHK Are Three Tailoring Iron Oxygenases for Amino Acid Building Blocks of the Echinocandin Scaffold
- (2013) Wei Jiang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A novell-isoleucine-4′-dioxygenase andl-isoleucine dihydroxylation cascade inPantoea ananatis
- (2013) Sergey V. Smirnov et al. MicrobiologyOpen
- l-Leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst
- (2012) Makoto Hibi et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- A novel family of bacterial dioxygenases that catalyse the hydroxylation of free l-amino acids
- (2012) Sergey V. Smirnov et al. FEMS MICROBIOLOGY LETTERS
- Halichonadins K and L, New Dimeric Sesquiterpenoids from a Sponge Halichondria sp.
- (2012) Naonobu Tanaka et al. ORGANIC LETTERS
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- (2011) Makoto Hibi et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine
- (2010) Sergey V. Smirnov et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Characterization of novel 2-oxoglutarate dependent dioxygenases converting l-proline to cis-4-hydroxy-l-proline
- (2009) Ryotaro Hara et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hydroxylation of l-proline to cis-3-hydroxy-l-proline by recombinant Escherichia coli expressing a synthetic l-proline-3-hydroxylase gene
- (2009) Robert M. Johnston et al. ENZYME AND MICROBIAL TECHNOLOGY
- Stereospecific Synthesis ofthreo- anderythro-β-Hydroxyglutamic Acid During Kutzneride Biosynthesis
- (2009) Matthias Strieker et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds
- (2009) John A. McIntosh et al. NATURAL PRODUCT REPORTS
- Stringency of the 2-His–1-Asp Active-Site Motif in Prolyl 4-Hydroxylase
- (2009) Kelly L. Gorres et al. PLoS One
- β-Hydroxylation of the Aspartyl Residue in the Phytotoxin Syringomycin E: Characterization of Two Candidate Hydroxylases AspH and SyrP inPseudomonas syringae†
- (2008) Gitanjali M. Singh et al. BIOCHEMISTRY
- Non-Heme Hydroxylase Engineering For Simple Enzymatic Synthesis ofL-threo-Hydroxyaspartic Acid
- (2008) Matthias Strieker et al. CHEMBIOCHEM
- Biosynthesis of (−)-(1S,2R)-Allocoronamic Acyl Thioester by an FeII-Dependent Halogenase and a Cyclopropane-Forming Flavoprotein
- (2008) Christopher S. Neumann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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