Cell type- and region-specific translatomes in an MPTP mouse model of Parkinson's disease

Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice

(2022) David J. Friedman et al.   JOURNAL OF IMMUNOLOGY

CREB Inactivation by HDAC1/PP1γ Contributes to Dopaminergic Neurodegeneration in Parkinson's Disease

(2022) Xiaoyi Xu et al.   JOURNAL OF NEUROSCIENCE

Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease

(2022) Tushar Kamath et al.   NATURE NEUROSCIENCE

Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson’s disease

(2022) Weizhao Chen et al.   eLife

The role of Toll-like receptors and neuroinflammation in Parkinson’s disease

(2022) Arash Heidari et al.   Journal of Neuroinflammation

Ablation of Siglec-E augments brain inflammation and ischemic injury

(2022) Lexiao Li et al.   Journal of Neuroinflammation

Mitochondrial Dysfunction in Parkinson’s Disease: From Mechanistic Insights to Therapy

(2022) Xiao-Yan Gao et al.   Frontiers in Aging Neuroscience

The role of Tumour Necrosis Factor in neuroinflammation associated with Parkinson's disease and targeted therapies

(2022) Ruhul Amin et al.   NEUROCHEMISTRY INTERNATIONAL

The role of prolactin in central nervous system inflammation

(2021) Edgar Ramos-Martinez et al.   REVIEWS IN THE NEUROSCIENCES

Astrocyte-specific expression of interleukin 23 leads to an aggravated phenotype and enhanced inflammatory response with B cell accumulation in the EAE model

(2021) Louisa Nitsch et al.   Journal of Neuroinflammation

Parkinson's disease

(2021) Bastiaan R Bloem et al.   LANCET

Neuroinflammatory astrocyte subtypes in the mouse brain

(2021) Philip Hasel et al.   NATURE NEUROSCIENCE

Nurr1 downregulation is caused by CREB inactivation in a Parkinson’s disease mouse model

(2021) Xiaoyi Xu et al.   NEUROSCIENCE LETTERS

Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson’s disease

(2021) Hideaki Matsui et al.   Nature Communications

ST8Sia6 Promotes Tumor Growth in Mice by Inhibiting Immune Responses

(2021) David J. Friedman et al.   Cancer Immunology Research

Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state

(2021) Semra Smajić et al.   BRAIN

Cellular origins of dsRNA, their recognition and consequences

(2021) Y. Grace Chen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of Nuclear factor kappa B (NF-κB) Signalling in Neurodegenerative Diseases: An Mechanistic Approach

(2020) Shareen Singh et al.   Current Neuropharmacology

Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice

(2020) Christine Klaus et al.   NEUROBIOLOGY OF AGING

Cutting Edge: ST8Sia6-Generated α-2,8-Disialic Acids Mitigate Hyperglycemia in Multiple Low-Dose Streptozotocin–Induced Diabetes

(2020) Paul J. Belmonte et al.   JOURNAL OF IMMUNOLOGY

Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain

(2020) Jinar Rostami et al.   Journal of Neuroinflammation

Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration

(2020) Insup Choi et al.   Nature Communications

Glia Crosstalk in Neuroinflammatory Diseases

(2020) Ada Bernaus et al.   Frontiers in Cellular Neuroscience

Inter and Intracellular mitochondrial trafficking in health and disease

(2020) Santhanam Shanmughapriya et al.   AGEING RESEARCH REVIEWS

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

(2020) Chien-Hsiung Yu et al.   CELL

Bile Acid Signaling in Neurodegenerative and Neurological Disorders

(2020) Stephanie M. Grant et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glycosphingolipids and neuroinflammation in Parkinson’s disease

(2020) Karim Belarbi et al.   Molecular Neurodegeneration

Cell type-specific lipid storage changes in Parkinson’s disease patient brains are recapitulated by experimental glycolipid disturbance

(2020) Oeystein Roed Brekk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

(2020) Devika Agarwal et al.   Nature Communications

Interleukin-17A: The Key Cytokine in Neurodegenerative Diseases

(2020) Junjue Chen et al.   Frontiers in Aging Neuroscience

Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases

(2020) An-Guo Wu et al.   AGEING RESEARCH REVIEWS

Mitochondrial Dysfunction and Mitophagy in Parkinson’s Disease: From Mechanism to Therapy

(2020) Ana Belen Malpartida et al.   TRENDS IN BIOCHEMICAL SCIENCES

Challenges in unsupervised clustering of single-cell RNA-seq data

(2019) Vladimir Yu Kiselev et al.   NATURE REVIEWS GENETICS

Crosstalk between soluble PDGF-BB and PDGFRβ promotes astrocytic activation and synaptic recovery in the hippocampus after subarachnoid hemorrhage

(2019) Xiaoming Zhou et al.   FASEB JOURNAL

Cytosolic sensing of immuno-stimulatory DNA, the enemy within

(2018) Rekha Dhanwani et al.   CURRENT OPINION IN IMMUNOLOGY

Early activation of Egr-1 promotes neuroinflammation and dopaminergic neurodegeneration in an experimental model of Parkinson's disease

(2018) Qing Yu et al.   EXPERIMENTAL NEUROLOGY

Signaling Pathways Involved in the Regulation of mRNA Translation

(2018) Philippe P. Roux et al.   MOLECULAR AND CELLULAR BIOLOGY

Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

(2018) Zhana Haimon et al.   NATURE IMMUNOLOGY

The Glycoscience of Immunity

(2018) Julie Y. Zhou et al.   TRENDS IN IMMUNOLOGY

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

(2018) Ashish Dhir et al.   NATURE

Parkin and PINK1 mitigate STING-induced inflammation

(2018) Danielle A. Sliter et al.   NATURE

A therapeutic approach to pantothenate kinase associated neurodegeneration

(2018) Lalit Kumar Sharma et al.   Nature Communications

c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson’s Disease

(2018) Kunhua Hu et al.   NEUROSCIENCE

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(2017) J.A. Obeso et al.   MOVEMENT DISORDERS

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

JNK-mediated activation of ATF2 contributes to dopaminergic neurodegeneration in the MPTP mouse model of Parkinson's disease

(2016) Qiaoying Huang et al.   EXPERIMENTAL NEUROLOGY

New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo

(2016) Rahul Srinivasan et al.   NEURON

CXCR3 ligands in disease and therapy

(2015) Katrien Van Raemdonck et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease

(2015) S.-M. Oh et al.   EMBO Molecular Medicine

Mitochondrial DNA stress primes the antiviral innate immune response

(2015) A. Phillip West et al.   NATURE

Identification of neurodegenerative factors using translatome–regulatory network analysis

(2015) Lars Brichta et al.   NATURE NEUROSCIENCE

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Cell type–specific mRNA purification by translating ribosome affinity purification (TRAP)

(2014) Myriam Heiman et al.   Nature Protocols

Microglial CD33-Related Siglec-E Inhibits Neurotoxicity by Preventing the Phagocytosis-Associated Oxidative Burst

(2013) J. Claude et al.   JOURNAL OF NEUROSCIENCE

Roles of FGF20 in dopaminergic neurons and Parkinson's disease

(2013) Nobuyuki Itoh et al.   Frontiers in Molecular Neuroscience

Mkp1 Is a c-Jun Target Gene That Antagonizes JNK-Dependent Apoptosis in Sympathetic Neurons

(2010) M. Kristiansen et al.   JOURNAL OF NEUROSCIENCE

Cell-type-specific isolation of ribosome-associated mRNA from complex tissues

(2009) E. Sanz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activating transcription factor 3 up-regulated by c-Jun NH2-terminal kinase/c-Jun contributes to apoptosis induced by potassium deprivation in cerebellar granule neurons

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