Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson’s disease
出版年份 2022 全文链接
标题
Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson’s disease
作者
关键词
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出版物
eLife
Volume 11, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2022-05-10
DOI
10.7554/elife.75636
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression
- (2022) David Leib et al. MOLECULAR THERAPY
- A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum
- (2022) Yunjia Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting PTB as a One-Step Procedure for In Situ Astrocyte-to-Dopamine Neuron Reprogramming in Parkinson’s Disease
- (2021) Yuanyuan Jiang et al. Neuroscience Bulletin
- Therapeutically viable generation of neurons with antisense oligonucleotide suppression of PTB
- (2021) Roy Maimon et al. NATURE NEUROSCIENCE
- AAV ablates neurogenesis in the adult murine hippocampus
- (2021) Stephen Johnston et al. eLife
- Revisiting astrocyte to neuron conversion with lineage tracing in vivo
- (2021) Lei-Lei Wang et al. CELL
- Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy
- (2021) Célia Lentini et al. Cell Stem Cell
- Neuroregenerative gene therapy to treat temporal lobe epilepsy in a rat model
- (2021) Jiajun Zheng et al. PROGRESS IN NEUROBIOLOGY
- Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington’s disease
- (2020) Zheng Wu et al. Nature Communications
- Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice
- (2020) Haibo Zhou et al. CELL
- NeuroD1 overexpression in spinal neurons accelerates axonal regeneration after sciatic nerve injury
- (2020) Muhua Lai et al. EXPERIMENTAL NEUROLOGY
- Method to combat Parkinson’s disease by astrocyte-to-neuron conversion
- (2020) Ernest Arenas NATURE
- Reversing a model of Parkinson’s disease with in situ converted nigral neurons
- (2020) Hao Qian et al. NATURE
- Metformin regulates astrocyte reactivity in Parkinson's disease and normal aging
- (2020) Young-Kyoung Ryu et al. NEUROPHARMACOLOGY
- In vivo glial trans‐differentiation for neuronal replacement and functional recovery in central nervous system
- (2020) Cheng Qian et al. FEBS Journal
- Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling
- (2020) Germán Belenguer et al. Cell Stem Cell
- A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In Vivo Astrocyte-to-Neuron Conversion
- (2019) Yu-Chen Chen et al. MOLECULAR THERAPY
- Inducing Different Neuronal Subtypes from Astrocytes in the Injured Mouse Cerebral Cortex
- (2019) Nicola Mattugini et al. NEURON
- Early activation of Egr-1 promotes neuroinflammation and dopaminergic neurodegeneration in an experimental model of Parkinson's disease
- (2018) Qing Yu et al. EXPERIMENTAL NEUROLOGY
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson’s Disease
- (2018) Kunhua Hu et al. NEUROSCIENCE
- Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons
- (2017) Marc S. Weinberg et al. MOLECULAR THERAPY
- Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model
- (2017) Pia Rivetti di Val Cervo et al. NATURE BIOTECHNOLOGY
- Direct Reprogramming of Resident NG2 Glia into Neurons with Properties of Fast-Spiking Parvalbumin-Containing Interneurons
- (2017) Maria Pereira et al. Stem Cell Reports
- NEUROD1 Instructs Neuronal Conversion in Non-Reactive Astrocytes
- (2017) Rebecca Brulet et al. Stem Cell Reports
- Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming
- (2016) Sergio Gascón et al. Cell Stem Cell
- New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo
- (2016) Rahul Srinivasan et al. NEURON
- The p53 Pathway Controls SOX2-Mediated Reprogramming in the Adult Mouse Spinal Cord
- (2016) Lei-Lei Wang et al. Cell Reports
- Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo
- (2015) Y. Liu et al. JOURNAL OF NEUROSCIENCE
- In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry
- (2015) Olof Torper et al. Cell Reports
- SOX2 Reprograms Resident Astrocytes into Neural Progenitors in the Adult Brain
- (2015) Wenze Niu et al. Stem Cell Reports
- A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse
- (2014) J. P. Magnusson et al. SCIENCE
- In vivo conversion of astrocytes to neurons in the injured adult spinal cord
- (2014) Zhida Su et al. Nature Communications
- Retinal Injury, Growth Factors, and Cytokines Converge on β-Catenin and pStat3 Signaling to Stimulate Retina Regeneration
- (2014) Jin Wan et al. Cell Reports
- Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex
- (2014) Christophe Heinrich et al. Stem Cell Reports
- Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog
- (2013) Swetlana Sirko et al. Cell Stem Cell
- In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model
- (2013) Ziyuan Guo et al. Cell Stem Cell
- In vivo reprogramming of astrocytes to neuroblasts in the adult brain
- (2013) Wenze Niu et al. NATURE CELL BIOLOGY
- Generation of induced neurons via direct conversion in vivo
- (2013) O. Torper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Environmental impact on direct neuronal reprogramming in vivo in the adult brain
- (2013) Andrew Grande et al. Nature Communications
- Lineage Tracing
- (2012) Kai Kretzschmar et al. CELL
- Self-Renewal and Differentiation of Reactive Astrocyte-Derived Neural Stem/Progenitor Cells Isolated from the Cortical Peri-Infarct Area after Stroke
- (2012) I. S. Shimada et al. JOURNAL OF NEUROSCIENCE
- Reactive Astrogliosis after Spinal Cord Injury—Beneficial and Detrimental Effects
- (2012) Soheila Karimi-Abdolrezaee et al. MOLECULAR NEUROBIOLOGY
- The stem cell potential of glia: lessons from reactive gliosis
- (2011) Stefanie Robel et al. NATURE REVIEWS NEUROSCIENCE
- Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction
- (2010) Keigan M. Park et al. CELLULAR SIGNALLING
- Cell-type-specific isolation of ribosome-associated mRNA from complex tissues
- (2009) E. Sanz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain
- (2008) A. Buffo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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