The Cutting Edge of Epigenetic Clocks: In Search of Mechanisms Linking Aging and Mental Health
出版年份 2023 全文链接
标题
The Cutting Edge of Epigenetic Clocks: In Search of Mechanisms Linking Aging and Mental Health
作者
关键词
-
出版物
BIOLOGICAL PSYCHIATRY
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2023-02-09
DOI
10.1016/j.biopsych.2023.02.001
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases
- (2023) Gabriel Sturm et al. Communications Biology
- Tick tock, tick tock: Mouse culture and tissue aging captured by an epigenetic clock
- (2022) Christopher Minteer et al. AGING CELL
- The Impact of Psychosocial Stress from Life Trauma and Racial Discrimination on Epigenetic Aging—A Systematic Review
- (2022) Sungju Lim et al. Biological Research for Nursing
- Early adversities accelerate epigenetic aging into adulthood: a 10‐year, within‐subject analysis
- (2022) William E. Copeland et al. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
- Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling
- (2022) Lucas A. Salas et al. Nature Communications
- A mammalian methylation array for profiling methylation levels at conserved sequences
- (2022) Adriana Arneson et al. Nature Communications
- DunedinPACE, a DNA methylation biomarker of the pace of aging
- (2022) Daniel W Belsky et al. eLife
- Longitudinal Associations of Mental Disorders With Dementia
- (2022) Leah S. Richmond-Rakerd et al. JAMA Psychiatry
- Making sense of the ageing methylome
- (2022) Kirsten Seale et al. NATURE REVIEWS GENETICS
- Temporal trends in associations between severe mental illness and risk of cardiovascular disease: A systematic review and meta-analysis
- (2022) Amanda M Lambert et al. PLOS MEDICINE
- Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer’s disease
- (2022) Kyra L. Thrush et al. Aging-US
- Additive effects of stress and alcohol exposure on accelerated epigenetic aging in Alcohol Use Disorder
- (2022) Jeesun Jung et al. BIOLOGICAL PSYCHIATRY
- Measuring biological age using omics data
- (2022) Jarod Rutledge et al. NATURE REVIEWS GENETICS
- Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health
- (2022) Danni A. Gadd et al. Nature Communications
- Serotonin and dopamine modulate aging in response to food odor and availability
- (2022) Hillary A. Miller et al. Nature Communications
- Epigenetic GrimAge acceleration and cognitive impairment in bipolar disorder
- (2022) Camila N.C. Lima et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- The immune factors driving DNA methylation variation in human blood
- (2022) Jacob Bergstedt et al. Nature Communications
- For whom the bell tolls: psychopathological and neurobiological correlates of a DNA methylation index of time-to-death
- (2022) Sage E. Hawn et al. Translational Psychiatry
- Dimensions of childhood adversity differentially affect biological aging in major depression
- (2022) Ryan Rampersaud et al. Translational Psychiatry
- Epigenetic aging and perceived psychological stress in old age
- (2022) Valentin Max Vetter et al. Translational Psychiatry
- Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice
- (2022) Kan Xie et al. Nature Communications
- Cell division drives DNA methylation loss in late-replicating domains in primary human cells
- (2022) Jamie L. Endicott et al. Nature Communications
- A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations
- (2022) Gabriel Sturm et al. Scientific Data
- Aging biomarkers and the brain
- (2021) Albert T. Higgins-Chen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Genetic architecture of schizophrenia: a review of major advancements
- (2021) Sophie E. Legge et al. PSYCHOLOGICAL MEDICINE
- DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia
- (2021) Eilis Hannon et al. eLife
- An integrative study of five biological clocks in somatic and mental health
- (2021) Rick Jansen et al. eLife
- Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial
- (2021) Kara N. Fitzgerald et al. Aging-US
- Heterochromatin and Polycomb as regulators of haematopoiesis
- (2021) Christine R. Keenan BIOCHEMICAL SOCIETY TRANSACTIONS
- Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
- (2021) James K. Nuñez et al. CELL
- The roles of Polycomb repressive complexes in mammalian development and cancer
- (2021) Andrea Piunti et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Accelerated aging in the brain, epigenetic aging in blood, and polygenic risk for schizophrenia
- (2021) Jalmar Teeuw et al. SCHIZOPHRENIA RESEARCH
- Importance of circadian timing for aging and longevity
- (2021) Victoria A. Acosta-Rodríguez et al. Nature Communications
- A systematic review of biological, social and environmental factors associated with epigenetic clock acceleration
- (2021) Lara Oblak et al. AGEING RESEARCH REVIEWS
- DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study
- (2021) Giovanni Fiorito et al. AGING CELL
- Clonal hematopoiesis associated with epigenetic aging and clinical outcomes
- (2021) Daniel Nachun et al. AGING CELL
- Accelerated Epigenetic Aging in Peripheral Blood Does not Predict Dementia Risk
- (2021) P.D. Fransquet et al. Current Alzheimer Research
- The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study
- (2021) Lauren L. Schmitz et al. Epigenetics
- The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure
- (2021) Felix Dammering et al. Neurobiology of Stress
- Postpartum sleep loss and accelerated epigenetic aging
- (2021) Judith E. Carroll et al. Sleep Health
- Aging biological markers in a cohort of antipsychotic-naïve first-episode psychosis patients
- (2021) Fernanda Talarico et al. PSYCHONEUROENDOCRINOLOGY
- Cortisol trajectories measured prospectively across thirty years of female development following exposure to childhood sexual abuse: Moderation by epigenetic age acceleration at midlife
- (2021) Chad E. Shenk et al. PSYCHONEUROENDOCRINOLOGY
- Psychological and biological resilience modulates the effects of stress on epigenetic aging
- (2021) Zachary M. Harvanek et al. Translational Psychiatry
- Misexpression of genes lacking CpG islands drives degenerative changes during aging
- (2021) Jun-Yeong Lee et al. Science Advances
- Psychosocial Stressors and Telomere Length: A Current Review of the Science
- (2020) Kelly E. Rentscher et al. Annual Review of Public Health
- Schizophrenia and Epigenetic Aging Biomarkers: Increased Mortality, Reduced Cancer Risk, and Unique Clozapine Effects
- (2020) Albert T. Higgins-Chen et al. BIOLOGICAL PSYCHIATRY
- Personal aging markers and ageotypes revealed by deep longitudinal profiling
- (2020) Sara Ahadi et al. NATURE MEDICINE
- mTOR at the nexus of nutrition, growth, ageing and disease
- (2020) Grace Y. Liu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- 20‐year follow‐up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20)
- (2020) Heidi Taipale et al. World Psychiatry
- Circadian rhythm disruption and mental health
- (2020) William H. Walker et al. Translational Psychiatry
- Current perspectives on the cellular and molecular features of epigenetic ageing
- (2020) Kenneth Raj et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity
- (2020) Seyma Katrinli et al. NEUROPSYCHOPHARMACOLOGY
- Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder
- (2020) Satoshi Okazaki et al. Translational Psychiatry
- A comparison of epigenetic mitotic-like clocks for cancer risk prediction
- (2020) Andrew E. Teschendorff Genome Medicine
- The geroscience agenda: Toxic stress, hormetic stress, and the rate of aging
- (2020) Elissa S. Epel AGEING RESEARCH REVIEWS
- Underlying features of epigenetic aging clocks in vivo and in vitro
- (2020) Zuyun Liu et al. AGING CELL
- Heterochromatin: an epigenetic point of view in aging
- (2020) Jong-Hyuk Lee et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes
- (2020) Chenglong You et al. Nature Communications
- Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs
- (2020) Christina A. Castellani et al. Genome Medicine
- GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality
- (2020) Cathal McCrory et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Reprogramming to recover youthful epigenetic information and restore vision
- (2020) Yuancheng Lu et al. NATURE
- NAD+ metabolism and its roles in cellular processes during ageing
- (2020) Anthony J. Covarrubias et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Epigenetic Age Acceleration Was Delayed in Schizophrenia
- (2020) Xiaohui Wu et al. SCHIZOPHRENIA BULLETIN
- Biological aging in schizophrenia and psychosis severity: DNA methylation analysis
- (2020) Oluwagbenga Dada et al. PSYCHIATRY RESEARCH
- DNA methylation GrimAge strongly predicts lifespan and healthspan
- (2019) Ake T. Lu et al. Aging-US
- Risperidone effects on heterochromatin: the role of kinase signaling
- (2019) B. Feiner et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk
- (2019) Anthony S. Zannas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging
- (2019) Georges E. Janssens et al. Cell Reports
- Somatic mutation and clonal expansions in human tissues
- (2019) Inigo Martincorena Genome Medicine
- From discoveries in ageing research to therapeutics for healthy ageing
- (2019) Judith Campisi et al. NATURE
- Methylation age acceleration does not predict mortality in schizophrenia
- (2019) Kaarina Kowalec et al. Translational Psychiatry
- Reversal of epigenetic aging and immunosenescent trends in humans
- (2019) Gregory M. Fahy et al. AGING CELL
- DNA methylation-based estimator of telomere length
- (2019) Ake T. Lu et al. Aging-US
- Neurobiological divergence of the positive and negative schizophrenia subtypes identified upon a new factor-structure of psychopathology using non-negative factorization: An international machine-learning study
- (2019) Ji Chen et al. BIOLOGICAL PSYCHIATRY
- Clonal hematopoiesis in human aging and disease
- (2019) Siddhartha Jaiswal et al. SCIENCE
- An epigenetic predictor of death captures multi-modal measures of brain health
- (2019) Robert F. Hillary et al. MOLECULAR PSYCHIATRY
- Distinct chromatin signatures of DNA hypomethylation in aging and cancer
- (2018) Raúl F. Pérez et al. AGING CELL
- An epigenetic biomarker of aging for lifespan and healthspan
- (2018) Morgan E. Levine et al. Aging-US
- Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies
- (2018) Rebecca B Lawn et al. HUMAN MOLECULAR GENETICS
- DNA methylation loss in late-replicating domains is linked to mitotic cell division
- (2018) Wanding Zhou et al. NATURE GENETICS
- DNA methylation-based biomarkers and the epigenetic clock theory of ageing
- (2018) Steve Horvath et al. NATURE REVIEWS GENETICS
- Posttraumatic psychopathology and the pace of the epigenetic clock: a longitudinal investigation
- (2018) Erika J. Wolf et al. PSYCHOLOGICAL MEDICINE
- Psychological Stress and Mitochondria
- (2018) Martin Picard et al. PSYCHOSOMATIC MEDICINE
- The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents
- (2018) Anna Suarez et al. Clinical Epigenetics
- Time and the Metrics of Aging
- (2018) Luigi Ferrucci et al. CIRCULATION RESEARCH
- Second generation atypical antipsychotics olanzapine and aripiprazole reduce expression and secretion of inflammatory cytokines in human immune cells
- (2018) Britta Stapel et al. JOURNAL OF PSYCHIATRIC RESEARCH
- EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia
- (2018) Andrea L. Johnstone et al. NEUROBIOLOGY OF DISEASE
- Cell and tissue type independent age-associated DNA methylation changes are not rare but common
- (2018) Tianyu Zhu et al. Aging-US
- Identification of differentially methylated cell types in epigenome-wide association studies
- (2018) Shijie C. Zheng et al. NATURE METHODS
- Accelerated DNA Methylation Age
- (2017) Erika J. Wolf et al. PSYCHOSOMATIC MEDICINE
- Systemic Biomarkers of Accelerated Aging in Schizophrenia: A Critical Review and Future Directions
- (2017) Tanya T Nguyen et al. SCHIZOPHRENIA BULLETIN
- Mitochondrial toxicity of tobacco smoke and air pollution
- (2017) Jessica L. Fetterman et al. TOXICOLOGY
- Traumatic Stress and Accelerated Cellular Aging: From Epigenetics to Cardiometabolic Disease
- (2017) Erika J. Wolf et al. Current Psychiatry Reports
- Biological Age Predictors
- (2017) Juulia Jylhävä et al. EBioMedicine
- DNA methylation age is not accelerated in brain or blood of subjects with schizophrenia
- (2017) Brandon C. McKinney et al. SCHIZOPHRENIA RESEARCH
- DNA methylation-based measures of biological age: meta-analysis predicting time to death
- (2016) Brian H. Chen et al. Aging-US
- Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers
- (2016) Brett A. Clementz et al. AMERICAN JOURNAL OF PSYCHIATRY
- Energetic stress: The reciprocal relationship between energy availability and the stress response
- (2016) C.S. Harrell et al. PHYSIOLOGY & BEHAVIOR
- The NIMH Research Domain Criteria Initiative: Background, Issues, and Pragmatics
- (2016) Michael J. Kozak et al. PSYCHOPHYSIOLOGY
- Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder
- (2015) Marco P. Boks et al. PSYCHONEUROENDOCRINOLOGY
- Association of telomere length and mitochondrial DNA copy number with risperidone treatment response in first-episode antipsychotic-naïve schizophrenia
- (2015) Zongchang Li et al. Scientific Reports
- An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging
- (2015) Tian Yuan et al. PLoS Genetics
- Mortality in Mental Disorders and Global Disease Burden Implications
- (2015) Elizabeth Reisinger Walker et al. JAMA Psychiatry
- Schizophrenia
- (2015) René S. Kahn et al. Nature Reviews Disease Primers
- Krebs cycle dysfunction shapes epigenetic landscape of chromatin: Novel insights into mitochondrial regulation of aging process
- (2014) Antero Salminen et al. CELLULAR SIGNALLING
- A pharmacological network for lifespan extension inCaenorhabditis elegans
- (2013) Xiaolan Ye et al. AGING CELL
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- The gap in life expectancy from preventable physical illness in psychiatric patients in Western Australia: retrospective analysis of population based registers
- (2013) D. Lawrence et al. BMJ-British Medical Journal
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- Current status and future prospects for epigenetic psychopharmacology
- (2012) Marco P. Boks et al. Epigenetics
- Clozapine and lithium require Caenorhabditis elegans β-arrestin and serum- and glucocorticoid-inducible kinase to affect Daf-16 (Foxo) localization
- (2011) Kathrine R. Weeks et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Review: Cancer and schizophrenia: is there a paradox?
- (2010) Richard Hodgson et al. JOURNAL OF PSYCHOPHARMACOLOGY
- DNA methylation landscapes: provocative insights from epigenomics
- (2008) Miho M. Suzuki et al. NATURE REVIEWS GENETICS
- Is Schizophrenia a Syndrome of Accelerated Aging?
- (2007) B. Kirkpatrick et al. SCHIZOPHRENIA BULLETIN
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