Association Between Metformin Use and Cognitive and Physical Function in Persons with HIV and Diabetes

Diabetes mellitus is associated with declines in physical function among men with and without HIV

(2022) Mary Clare et al.   AIDS

LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy

(2021) Delphine Planas et al.   EBioMedicine

Metformin alters skeletal muscle transcriptome adaptations to resistance training in older adults

(2020) Ameya S. Kulkarni et al.   Aging-US

Impaired insulin sensitivity is associated with worsening cognition in HIV-infected patients

(2019) Saja S. Khuder et al.   NEUROLOGY

Hyperglycemia and metformin use are associated with B-vitamin deficiency and cognitive dysfunction in older adults

(2019) Kirsty M Porter et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Neurocognitive Deficits in a Cohort With Class 2 and Class 3 Obesity: Contributions of Type 2 Diabetes and Other Comorbidities

(2019) Heshan J. Fernando et al.   Obesity

Association Between Metformin Initiation and Incident Dementia Among African American and White Veterans Health Administration Patients

(2019) Jeffrey F. Scherrer et al.   ANNALS OF FAMILY MEDICINE

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double‐blind, placebo‐controlled, multicenter trial: The MASTERS trial

(2019) R. Grace Walton et al.   AGING CELL

Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7

(2018) Jingqi Fang et al.   AGING CELL

Impact of glycemic status on longitudinal cognitive performance in men with and without HIV Infection

(2018) Jingyan Yang et al.   AIDS

Frailty, Neurocognitive Impairment, or Both in Predicting Poor Health Outcomes Among Adults Living With Human Immunodeficiency Virus

(2018) Kristine M Erlandson et al.   CLINICAL INFECTIOUS DISEASES

Long-Term Metformin Usage and Cognitive Function among Older Adults with Diabetes

(2018) Tze Pin Ng et al.   JOURNAL OF ALZHEIMERS DISEASE

Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity

(2017) Takahiro Horiuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association Between Frailty and Components of the Frailty Phenotype With Modifiable Risk Factors and Antiretroviral Therapy

(2017) Kristine M. Erlandson et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of HIV-infection and cumulative viral load on age-related decline in grip strength

(2016) Jennifer A. Schrack et al.   AIDS

Metformin as a Tool to Target Aging

(2016) Nir Barzilai et al.   Cell Metabolism

Impact of Metformin on Exercise-Induced Metabolic Adaptations to Lower Type 2 Diabetes Risk

(2016) Steven K. Malin et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Metformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical Trial

(2016) José A. Luchsinger et al.   JOURNAL OF ALZHEIMERS DISEASE

Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study

(2016) Vanita R. Aroda et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inflammation, Immune Activation, Immunosenescence, and Hormonal Biomarkers in the Frailty-Related Phenotype of Men with or at Risk for HIV

(2016) Kristine M. Erlandson et al.   JOURNAL OF INFECTIOUS DISEASES

Accelerated Longitudinal Gait Speed Decline in HIV-Infected Older Men

(2015) Jennifer A. Schrack et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Metformin activates a duodenal Ampk–dependent pathway to lower hepatic glucose production in rats

(2015) Frank A Duca et al.   NATURE MEDICINE

Metformin and Inflammation: Its Potential Beyond Glucose-lowering Effect

(2015) Yoshifumi Saisho   Endocrine Metabolic & Immune Disorders-Drug Targets

Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway

(2015) Kumsun Cho et al.   Scientific Reports

Relationship of physical function and quality of life among persons aging with HIV infection

(2014) Kristine M. Erlandson et al.   AIDS

Type 2 Diabetes and Antidiabetic Medications in Relation to Dementia Diagnosis

(2014) Chin Cheng et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Metformin lowers Ser-129 phosphorylated α-synuclein levels via mTOR-dependent protein phosphatase 2A activation

(2014) B I Pérez-Revuelta et al.   Cell Death & Disease

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation

(2013) Olga Moiseeva et al.   AGING CELL

Systemic Effects of Inflammation on Health during Chronic HIV Infection

(2013) Steven G. Deeks et al.   IMMUNITY

Quadriceps Strength, Quadriceps Power, and Gait Speed in Older U.S. Adults with Diabetes Mellitus: Results from the National Health and Nutrition Examination Survey, 1999-2002

(2013) Rita Rastogi Kalyani et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Morbidity and Aging in HIV-Infected Persons: The Swiss HIV Cohort Study

(2011) B. Hasse et al.   CLINICAL INFECTIOUS DISEASES

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

Inverse association between insulin resistance and gait speed in nondiabetic older men: results from the U.S. National Health and Nutrition Examination Survey (NHANES) 1999-2002

(2009) Chen-Ko Kuo et al.   BMC Geriatrics

AIDS Clinical Trials Group Longitudinal Linked Randomized Trials (ALLRT): Rationale, Design, and Baseline Characteristics

(2008) Marlene Smurzynski et al.   HIV CLINICAL TRIALS